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VASP


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Gene DB Home
Symbol:VASP
Name(s):vasodilator-stimulated phosphoprotein
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18064332 Determination of VASP phosphorylation is superior to conventional platelet aggregometry and angiographic parameters for assessing the risk of stent thrombosis.
18217157 VASP phosphorylation demonstrated concordance across the response range of P2Y(12) receptor blockade following thienopyridine administration.
17938817 VASP has a role in increased impaired platelet responsiveness in patients with subacute stent thrombosis
17351763 RSV resistance in a minority of clones was due to mono-allelic disruption of the cellular gene for VASP.
17914456 analysis of the structural basis of profilin-actin complexes during filament elongation by Ena/VASP
17488353 VASP phosphorylation may have a role in the individual response to clopidogrel loading dose prior to percutaneous coronary intervention
12397215 These results suggest that VASP may participate in vasculogenesis and endothelial sprouting during placental vasculogenesis
15569942 The basis for the right-handed geometry of VASP TD is a 15-residue repeat in its amino acid sequence, which reveals a characteristic pattern of hydrophobic residues
16046415 Galpha13-induced VASP phosphorylation that involves activation of RhoA and MEKK1, phosphorylation and degradation of IkappaB, release of PKA catalytic subunit from the complex with IkappaB and NF-kappaB, and subsequent phosphorylation of VASP
15634270 VASP is phosphorylated in patients with ischemic cardiovascular diseases and clopidogrel resistance

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDFYBvasodilator-stimulated phosphoprotein--Pubmed
HPRDFYN binding proteinVasodilator stimulated phosphoprotein--Pubmed
HPRDFYN binding protein isoform 1Vasodilator stimulated phosphoprotein--Pubmed
HPRDGelsolinvasodilator-stimulated phosphoprotein--Pubmed
HPRDgelsolin isoform a precursorVasodilator stimulated phosphoprotein--Pubmed
HPRDLIM domain containing preferred translocation partner in lipomavasodilator-stimulated phosphoprotein--Pubmed
HPRDLIM domain containing preferred translocation partner in lipomavasodilator-stimulated phosphoprotein--Pubmed
HPRDProfilin 1vasodilator-stimulated phosphoprotein--Pubmed
HPRDProlifin 2vasodilator-stimulated phosphoprotein--Pubmed
HPRDVasodilator stimulated phosphoproteinzyxin--Pubmed

Recent Publications on VASP:

Pubmed Logo
Actin filament nucleation and elongation factors - structure-function relationships.
The spontaneous and unregulated polymerization of actin filaments is...
31st October, 2009
Department of Physiology, University of Pennsylvania School of Medicine, Crit Rev Biochem Mol Biol. 2009 Oct 29.
DOI Direct Link
Effect of Focal Adhesion Proteins on Endothelial Cell Adhesion, Motility and Orientation Response to Cyclic Strain.
Focal adhesion proteins link cell surface integrins and intracellular...
27th October, 2009
Department of Biomedical Engineering, Washington University in St. Louis, Ann Biomed Eng. 2009 Oct 27.
DOI Direct Link
Listeria monocytogenes ActA is a key player in evading autophagic recognition.
Autophagy is a pivotal bulk degradation system that eliminates undesirable...
27th October, 2009
Department of Microbiology and Immunology, International Research Center Autophagy. 2009 Nov 26;5(8).
From Branched Networks of Actin Filaments to Bundles.
Cross-linking proteins can mediate the emergence of rigid bundles from a...
23rd October, 2009
Institute of Chemistry and Fritz Haber Center, Hebrew University, Chemphyschem. 2009 Oct 21.
DOI Direct Link
Exploring the Roles of Diaphanous and Enabled Activity in Shaping the Balance between Filopodia and Lamellipodia.
Monitoring Editor: Marcos Gonzalez-Gaitan During migration cell...
23rd October, 2009
Department of Biology and Lineberger Comprehensive Cancer Center, Mol Biol Cell. 2009 Oct 21.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Influence Of Omeprazole On The Anti-Platelet Action Of Clopidogrel

Patents:

Patents logo
US Patent No.Title
6979557 Full-length cDNA
7212621 Feature interactions
7238469 Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
7250250 POSH nucleic acids, polypeptides and related methods
7252950 Assays for detecting modulators of cytoskeletal function

View more patents.

VASP results (if any) from reagent suppliers

Google CSE Logo
Phospho-VASP (Ser157) Antibody #3111
Phospho-VASP (Ser157) Antibody detects endogenous levels of VASP only when phosphorylated at serine 157. The antibody may cross-react with the ...
http://www.cellsignal.com/products/3111.html...

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The Abcam catalog
VASP antibodies. ... VASP (phospho S157) antibody. IHC-P, WB, ELISA, ICC/IF ... VASP (phospho S239) antibody [16C2]. IP, WB, ELISA, ICC/IF. Mouse monoclonal ...
http://www.abcam.com/index.html?t=126640&pt=1&c=793...

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Phospho-VASP (Ser239) Antibody #3114
Phospho-VASP (Ser239) Antibody detects endogenous levels of VASP only when phosphorylated at serine 239. The antibody does not cross-react with ...
http://www.cellsignal.com/products/3114.html...

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VASP Antibody / VASP Antibodies
VASP Antibody / VASP Antibodies. ... VASP specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-vasp.html...

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Purified Anti-VASP Antibody - BioLegend
Purified Anti-VASP Antibody - VASP (vasodilator-stimulated phosphoprotein) is a 46 kD member of the Ena/VASP family that contains WH1, EVH1, ...
http://www.biolegend.com/purified-anti-vasp-antibody-2148.ht...

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p-VASP (Ser 239) Antibody sc-23507
See how others have used p-VASP (Ser 239): sc-23507 antibody and or ... Western blot analysis of VASP phosphorylation in human platelet extract (A,B). ...
http://www.scbt.com/datasheet-23507-p-vasp-ser-239-antibody....

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VASP (A290) Antibody
(VASP) was originally characterized as a substrate of both. cGMP- and cAMP- dependent kinases ... VASP belongs to the Ena/VASP family of adaptor proteins
...
http://www.cellsignal.com/pdf/3120.pdf...

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