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VBP1


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Gene DB Home
Symbol:VBP1
Name(s):von Hippel-Lindau binding protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:PFD3, PFDN3, VBP-1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17698809 VBP1 and cullin2/von Hippel-Lindau are required for proper HIV-1 expression at a step between integrase-dependent proviral integration into the host genome and transcription of viral genes
15063765 Thus, vHL/HIF-1alpha has a regulatory role in COX-2-mediated VEGF production in hypoxic stellate cells in injured liver.
15572213 The VHL binding protein have been shown to cause the myeloproliferative disorders .
12613020 binds to HIF-1 alpha and regulates the function of HIF-1 alpha
14729622 PTHrP is an essential growth factor for clear cell renal carcinoma and is a novel target for the von Hippel-Lindau tumor suppressor protein.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDmutS homolog 4von Hippel-Lindau binding protein 1--Pubmed
HPRDmutS homolog 4von Hippel-Lindau binding protein 1--Pubmed
BINDvon Hippel-Lindau binding protein 1von Hippel-Lindau tumor suppressor isoform 1The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with VBP1.-Pubmed

Recent Publications on VBP1:

Pubmed Logo
Uncommon clinical presentations of pheochromocytoma and paraganglioma in two different patients affected by two distinct novel VHL germline mutations.
CONTEXT: The von Hippel-Lindau (VHL) syndrome is an inherited multitumour...
16th September, 2009
Department of Clinical Physiopathology, Division of Endocrinology, Clin Endocrinol (Oxf). 2008 May;68(5):762-8. Epub 2007 Nov 19.
DOI Direct Link
[Von-Hippel-Lindau gene mutation types. Association of gene expression signatures in clear cell renal cell carcinoma]
AIMS: The von-Hippel-Lindau (VHL) tumor suppressor is a multifunctional...
22nd May, 2009
Institut fur Klinische Pathologie, UniversitatsSpital Zurich, Pathologe. 2008 Nov;29 Suppl 2:303-7.
DOI Direct Link
Yeast two-hybrid detection of integrase-host factor interactions.
Here we describe methods developed based on systematic yeast two-hybrid...
24th February, 2009
Hybrigenics S.A., 3-5 Impasse Reille, Paris 75014, France. Methods. 2009 Apr;47(4):291-7. Epub 2009 Feb 20.
DOI Direct Link
HIF and reactive oxygen species regulate oxidative phosphorylation in cancer.
A decrease in oxidative phosphorylation (OXPHOS) is characteristic of many...
5th September, 2008
Centre de Genetique Moleculaire et Cellulaire, UMR 5534, Centre National Carcinogenesis. 2008 Aug;29(8):1528-37. Epub 2008 May 29.
DOI Direct Link
Hepatitis B virus X protein enhances NFkappaB activity through cooperating with VBP1.
Hepatitis B virus X protein (HBx) is essential for hepatitis B virus...
20th May, 2008
Department of Microbiology, School of Bioscience and Biotechnology, BMB Rep. 2008 Feb 29;41(2):158-63.

View more research publications.

Patents:

Patents logo
US Patent No.Title
6597884 Image forming apparatus including electrostatic conveyance of charged toner
6982602 Low voltage input current mirror circuit and method
7002397 Method of setting back bias of MOS circuit, and MOS integrated circuit
7015841 Analog to digital converter circuit of successive approximation type operating at low voltage
7064621 Synchronous clock generation circuit capable of ensuring wide lock-in range and attaining lower jitter

View more patents.

VBP1 results (if any) from reagent suppliers

Google CSE Logo
prefoldin 3 (K-13) Antibody sc-19837
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, VBP1, 7411, Xq28, NM_003372 · P61758
...
http://www.scbt.com/datasheet-19837-prefoldin-3-k-13-antibod...

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3C-3E
Monoclonal Anti-VBP1 antibody produced in mouse clone 3D11, purified immunoglobulin, buffered aqueous solution, 3D11 (monoclonal) ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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prefoldin 3 (K-13) Antibody sc-19837
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, VBP1, 7411, Xq28, NM_003372 · P61758 ...
http://www.scbt.com/de/datasheet-19837-prefoldin-3-k-13-anti...

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prefoldin 3 (K-13) Antibody sc-19837
Humano, VBP1, 7411, Xq28, NM_003372 · P61758 · 300133. camundongo, Vbp1, 22327, X A7.3, P61759, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-19837-prefoldin-3-k-13-anti...

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prefoldin 3 (K-13) Antibody sc-19837
... Numéro d'accès de la protéine, Numéro OMIM™. Humain, VBP1, 7411, Xq28, NM_003372 · P61758 · 300133. Souris, Vbp1, 22327, X A7.3, P61759, Non disponible
...
http://www.scbt.com/fr/datasheet-19837-prefoldin-3-k-13-anti...

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