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VCL
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18028034 |
alpha-synemin, but not beta-synemin, interacts with both vinculin and metavinculin |
| 18056416 |
The expression of vinculin constructs with unmasked binding sites in the head and tail regions induces dramatic focal adhesion growth, which is mediated by their direct interaction with talin. |
| 17591693 |
Results decribe a mechanism in which signals from the T cell receptor produce WAVE2-ARP2/3-mediated de novo actin polymerization, leading to integrin clustering and high-affinity binding through the recruitment of vinculin and talin. |
| 17932491 |
analysis of vinculin binding in its closed conformation by a helix addition mechanism |
| 17709988 |
vinculin plays a role in growth regulation of neuroendocrine tumors and in expression of CLD4 |
| 15070891 |
Findings support a model in which talin binds to and activates multiple vinculin molecules to provoke rapid reorganization of the actin cytoskeleton. |
| 15883197 |
Beyond providing direct evidence that vinculin is activated at focal adhesions, this study shows that the specific functional conformation correlates with regional cellular dynamics. |
| 17088427 |
Invasin IpaA subverts vinculin's functions. Shigella flexneri utilizes a remarkable level of molecular mimicry of the talin-vinculin interaction to activate vinculin. |
| 14702644 |
crystal structures of human vinculin in its inactive and talin-activated states |
| 15988023 |
A model is suggested where vinculin's Vh1 domain acts as a molecular switch that undergoes distinct structural changes provoked by talin and alpha-actinin binding in focal adhesions versus adherens junctions, respectively. | →View more information from publications. |
Recent Publications on VCL: |  |
Influence of a 50 hz extra low frequency electromagnetic field on spermatozoa motility and fertilization rates in rabbits.
Effects of a 50 Hz extra-low frequency electromagnetic field (ELF EMF) on... | 30th October, 2009
| Department of Animal Physiology, Faculty of Biotechnology and Food
| J Environ Sci Health A Tox Hazard Subst Environ Eng. 2009
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VCL-CB01, an injectable bivalent plasmid DNA vaccine for potential protection against CMV disease and infection.
Vaccines for the prevention of human CMV (hCMV) infection and disease are... | 7th October, 2009
| University of Minnesota, Center for Infectious Diseases and Microbiology
| Curr Opin Mol Ther. 2009 Oct;11(5):572-8.
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Ability of Catalonian donkey sperm to penetrate zona pellucida-free bovine oocytes matured in vitro.
An experiment was designed to study the interaction between... | 15th September, 2009
| Departament de Medicina i Cirurgia Animals, Universitat Autonoma de
| Anim Reprod Sci. 2009 Aug 21.
DOI Direct Link |
[SHENG MAI ZHUSHEYE improves the viability and movement parameters of human sperm in vitro]
OBJECTIVE: To observe the effect of SHENG MAI ZHUSHEYE on the movement... | 4th September, 2009
| Department of Gynecology & Obstetrics, Weifang Maternal and Child Health
| Zhonghua Nan Ke Xue. 2009 May;15(5):468-71.
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Proteomic analysis of increased Parkin expression and its interactants provides evidence for a role in modulation of mitochondrial function.
Parkin is an ubiquitin-protein ligase (E3), mutations of which cause... | 3rd September, 2009
| Section of Ophthalmology and Neuroscience, Leeds Institute for Molecular
| Proteomics. 2009 Sep;9(18):4284-97.
DOI Direct Link |
→View more research publications. |
VCL results (if any) from reagent suppliers | 
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VCL monoclonal antibody (M01)
VCL (AAH39174, 1 a.a. ~ 1067 a.a) full length recombinant protein with GST tag. ... Immunofluorescence of monoclonal antibody to VCL (AT4505a) on HeLa cell ...
http://www.abgent.com/products/catalog_no/AT4505a_VCL_monocl...
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V9264 Monoclonal Anti-Vinculin ~1.0 mg/mL, clone hVIN-1, purified ...
VCL(7414). rat ... Vcl(305679). mouse ... Vcl(22330). shipped in, dry ice. storage temp. −20°C ... HPA002131, Anti-VCL antibody produced in rabbit ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=V926...
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V4139 Anti-Vinculin antibody produced in rabbit affinity isolated ...
Gene Information, human ... VCL(7414). rat ... Vcl(305679). mouse ... Vcl(22330) . shipped in, dry ice. storage temp. −20°C ...
https://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=V41...
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V4505 Monoclonal Anti-Vinculin antibody produced in mouse clone ...
Synonym: Anti-VCL. MDL number: MFCD00162905 ... Gene Information, human ... VCL( 7414). mouse ... Vcl(22330). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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vinculin (H-300) Antibody sc-5573
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, VCL, 7414, 10q22.2, NM_003373, ...
http://www.scbt.com/datasheet-5573-vinculin-h-300-antibody.h...
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F7053 Monoclonal Anti-Vinculin−FITC antibody produced in mouse ...
application(s), direct immunofluorescence: 1:50 using methanol/acetone fixed cultured bovine MDBK cells. isotype, IgG1. Gene Information, human ... VCL(7414
...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Monoclonal Antibody to Human Progesterone Receptor (Phospho-Ser 294)
... N.L., and Edwards, D.P.,Mol. Endocrinol., 14 (2000) 52 - 65. 2. Lin, V. C. L., Woon, C. T., Aw, S. E., Guo, C.,Endocrinology 144 (2003) 5650 -5657.
...
http://www.imgenex.com/antibody_details.php?catalog=IMG-682...
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