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VIPR2


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Symbol:VIPR2
Name(s):vasoactive intestinal peptide receptor 2
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ16511, VPAC2, VPCAP2R
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16888203 splice variants may modify the immunoregulatory contributions of the VIP-VPAC2 axis
16572459 VPAC2-R mRNA was visualized only in the cerebellum of 7-22-year-old subjects.
15302876 analysis of a mutant form of VPAC2 shows its role in signaling and ligand binding
16500728 a novel recombinant agonist for VPAC2 is not active against PAC1
16934434 identification and characterization of novel five-transmembrane(5TM) isoforms of VPAC2
15090046 Detection of beta-galactosidase marker for human VPAC2/VIPR2 in cells withinin the suprachiasmatic nucleus (SCN) of transgenic mice indicates that VPAC2 may contribute to autoregulation and/or coupling within the SCN core and to control of the SCN shell.
17077178 altered expression of VPAC2 in activated CD4+ T cells derived from multiple sclerosis (MS) patients rendered CD4+ T cells less responsive to VIP and skewed the system to a predominantly T(h)1 direction.
17257640 Daily stimulation of VPAC2, but not VPAC1 or PAC1, resulted in up to 90% inhibition of X4 or R5 productive infections in either cell lines or PBMCs.
16552823 The abnormal expression of VPCAP2-R mRNA in gallbladder tissue may play a role in the formation of gallbladder stones and gallbladder polyps

Recent Publications on VIPR2:

Pubmed Logo
Daily rhythms and sex differences in vasoactive intestinal polypeptide, VIPR2 receptor and arginine vasopressin mRNA in the suprachiasmatic nucleus of a diurnal rodent, Arvicanthis niloticus.
Diurnal and nocturnal animals differ with respect to the time of day at...
9th October, 2009
Veterinary Biosciences, University of Illinois, Urbana, IL, USA. Eur J Neurosci. 2009 Oct;30(8):1537-43. Epub 2009 Oct 7.
DOI Direct Link
The Neurotransmitter VIP Expands the Pool of Symmetrically Dividing Postnatal Dentate Gyrus Precursors via VPAC(2) Receptors or Directs Them Toward a Neuronal Fate via VPAC(1) receptors.
The controlled production of neurons in the postnatal dentate gyrus and...
4th August, 2009
Division of Clinical Neurosciences, University of Southampton, United Stem Cells. 2009 Oct;27(10):2539-2551.
DOI Direct Link
Potential immunomodulatory role of VIP in the implantation sites of prediabetic nonobese diabetic mice.
Among several factors known to modulate embryo implantation and survival,...
28th July, 2009
Immunopharmacology Laboratory, Department of Biological Chemistry, School Reproduction. 2009 Oct;138(4):733-42. Epub 2009 Jul 24.
DOI Direct Link
Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2-/- mice.
Vasoactive intestinal polypeptide and its receptor, VPAC(2), play...
16th September, 2008
Faculty of Life Sciences, University of Manchester, Manchester, UK. J Neurochem. 2008 Aug;106(4):1646-57. Epub 2008 Jun 28.
DOI Direct Link
Select cognitive deficits in vasoactive intestinal peptide deficient mice.
BACKGROUND: The neuropeptide vasoactive intestinal peptide (VIP) is widely...
30th August, 2008
Department of Psychiatry and Biobehavioral Sciences, University of BMC Neurosci. 2008 Jul 10;9:63.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7612186 Compositions and methods for producing recombinant proteins
6806054 Non-endogenous, constitutively activated known G protein-coupled receptors
6969702 Compounds and methods for increasing neurogenesis
7060275 Use of protein biomolecular targets in the treatment and visualization of brain tumors
7097969 Non-endogenous, constitutively activated known G protein-coupled receptors

View more patents.

VIPR2 results (if any) from reagent suppliers

Google CSE Logo
VIPR2. Mouse cln AS69 Monoclonal
16 Sep 2002 ... and function of VIPR1 and VIPR2. VIPR1 on tumor cells mediates ... "Structure of the human VIPR2 gene for vasoactive intestinal peptide ...
http://www.exalpha.com/pdfs/Z140M.pdf...

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VPAC2 (K-15) Antibody sc-15960
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, VIPR2, 7434, 7q36.3, NM_003382 ...
http://www.scbt.com/datasheet-15960-vpac2-k-15-antibody.html...

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Exalpha Biologicals, Inc.
No. A090M). Image of rat hippocampus stained using VIPR2 antibody, clone AS69 ( Cat. No. Z140M). © 2009 Exalpha Biologicals ...
http://www.exalpha.com/ImageLibrary.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
VIPR2; VIP2R; FLJ16511 - VIP-R-2; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=V...

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Exalpha Biologicals, Inc.
Z140M, VipR 2 (Vasoactive Intestinal Peptide Rec-2), Monoclonal Antibody, AS69, 100 µg, $300, Datasheet (pdf). © 2009 Exalpha Biologicals ...
http://www.exalpha.com/Searchresults1.php?menuvalue=Category...

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Antibodies to Neurotransmitter Receptors
purified immunoglobulin, human ... VIPR2(7434) rat ... Vipr2(29555), rat, human, IHC (f), WB, pricing. Sigma Aldrich Logo. Site Use Terms ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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VPAC2 Antibody / VPAC2 Antibodies
제품명, 카탈로그 번호, ISOTYPE, EPITOPE, APPLICATIONS, SPECIES. VPAC2 (AS69) Antibody, sc-52795, mouse IgG1, 105-122 (h), WB, h,r. VPAC2 (H-50) Antibody ...
http://www.scbt.com/ko/table-vpac2.html...

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