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VPREB1


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Gene DB Home
Symbol:VPREB1
Name(s):pre-B lymphocyte gene 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:IGI, IGVPB, VPREB
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11994467 The 5' region of the VpreB gene contains a promoter which displays higher relative activity in preB cells compared with cells at other stages or from other lineages.
16818733 Pre-B cell integrins and their stromal cell ligands together with the pre-B cell receptor and galectin-1 form a homogeneous lattice at the contact area between bone marrow pre-B and stromal cells.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDImmunoglobulin muimmunoglobulin iota chain preproprotein--Pubmed
HPRDunnamed protein productPreB lymphocyte gene 1--Pubmed

Recent Publications on VPREB1:

Pubmed Logo
Microarray analysis of gene expression profile by treatment of Cinnamomi Ramulus in lipopolysaccharide-stimulated BV-2 cells.
It has been reported that components of Cinnamomi Ramulus (CR) demonstrate...
3rd July, 2009
Department of Applied Eastern Medicine, Graduate School, Kyung Hee Gene. 2009 Aug 15;443(1-2):83-90. Epub 2009 May 5.
DOI Direct Link
A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study.
BACKGROUND: Genetic subtypes of acute lymphoblastic leukaemia (ALL) are...
4th March, 2009
Department of Paediatric Oncology and Haematology, Erasmus MC-Sophia Lancet Oncol. 2009 Feb;10(2):125-34. Epub 2009 Jan 8.
DOI Direct Link
The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes.
Early B cell factor (EBF) is a critical regulator of B lymphocyte-specific...
23rd October, 2008
Integrated Department of Immunology, National Jewish Medical and Research Mol Immunol. 2008 Aug;45(14):3786-96. Epub 2008 Jul 7.
DOI Direct Link
Cbfbeta-SMMHC impairs differentiation of common lymphoid progenitors and reveals an essential role for RUNX in early B-cell development.
The core-binding factor (CBF)-associated leukemia fusion protein...
28th March, 2008
Program in Gene Function and Expression, University of Massachusetts Blood. 2008 Feb 1;111(3):1543-51. Epub 2007 Oct 16.
DOI Direct Link
Molecular analysis of the pre-BCR complex in a large cohort of patients affected by autosomal-recessive agammaglobulinemia.
Autosomal-recessive agammaglobulinemia is a rare and heterogeneous...
10th July, 2007
Medical Genetics Unit and CRBa, S. Orsola-Malpighi University Hospital, Genes Immun. 2007 Jun;8(4):325-33. Epub 2007 Apr 5.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
7056736 Secreted and transmembrane polypeptides and nucleic acids encoding the same
7041804 Antibodies to PRO1387 polypeptides
7037679 Nucleic acids encoding PRO1184 polypeptides
7034136 Nucleic acids encoding PRO1159 polypeptides

View more patents.

VPREB1 results (if any) from reagent suppliers

Google CSE Logo
VpreB (F-14) Antibody sc-25010
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, VPREB1, 7441, 22q11.22, NM_007128 ...
http://www.scbt.com/datasheet-25010-vpreb-f-14-antibody.html...

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Abcam antibodies and reagents product map
... URP2 antibodies (3) · URP2 proteins and peptides (1) · VPREB1 antibodies (1) · WC5 antibodies (2) · ZNF43 antibodies (1) · pan B-cells antibodies (1) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=249...

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VpreB Antibody / VpreB Antibodies
製品名, カタログ番号, アイソタイプ, エピトープ, アプリケーション, 動物種. VpreB (5F251) 抗体, sc-73266, mouse IgG1, N/A, WB, IF, IHC(P), human ...
http://www.scbt.com/ja/table-vpreb.html...

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Abcam antibodies and reagents product map
... Transferrin Receptor proteins and peptides (1) · VPREB1 antibodies (1) · VPREB3 antibodies (1) · soluble IL2 Receptor beta antibodies (1) ...
http://www.abcam.com/index.html?pageconfig=productmap&cl=342...

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VpreB (M-17) Antibody sc-25014
goat polyclonal IgG, 200 µg/ml; epitope mapping at the C-terminus of VpreB of mouse origin; recommended for detection of VpreB1 and VpreB2 of m and r origin
...
http://www.scbt.com/it/datasheet-25014-vpreb-m-17-antibody.h...

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