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LAT2
| Symbol: | LAT2 | | Name(s): | linker for activation of T cells family, member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 14722116 |
LAB was primarily phosphorylated on three membrane-distal tyrosines, Tyr(136), Tyr(193), and Tyr(233). Mutation of these three tyrosines abolished Grb2 binding and LAB function |
| 12514734 |
LAB links BCR engagement to downstream signaling pathways. |
| 17277102 |
NTAL acts as a negative regulator of TNF-alpha and IL-8 production after stimulation via TREM-1 |
| 15745852 |
The NTAL/LAB is expressed in a variety of immune cells. |
| 15153499 |
LAB resembled a LAT molecule unable to bind phospholipase C-gamma1. |
| 12486104 |
data show that NTAL (non-T cell activation linker) appears to be a structural and possibly also functional homologue of LAT (linker for activation of T cells)in non-T cells [non-T cell activation linker] |
Recent Publications on LAT2: |  |
Progesterone and Mifepristone Regulate L-Type Amino Acid Transporter 2 and 4F2 Heavy Chain Expression in Uterine Leiomyoma Cells.
Context: Progesterone and its receptor (PR) play key roles in uterine... | 8th October, 2009
| Division of Reproductive Biology Research (X.L., P.Y., S.R., H.I., Z.L.,
| J Clin Endocrinol Metab. 2009 Oct 6.
DOI Direct Link |
Culture-induced changes in blood-brain barrier transcriptome: implications for amino-acid transporters in vivo.
Tight homeostatic control of brain amino acids (AA) depends on transport... | 29th September, 2009
| Theodor Kocher Institute, University of Bern, Bern, Switzerland.
| J Cereb Blood Flow Metab. 2009 Sep;29(9):1491-502. Epub 2009 Jun 3.
DOI Direct Link |
Glutamine inhibits ammonia-induced accumulation of cGMP in rat striatum limiting arginine supply for NO synthesis.
Brain L-glutamine (Gln) accumulation and increased activity of the NO/cGMP... | 15th September, 2009
| Department of Neurotoxicology, Mossakowski Medical Research Centre, Polish
| Neurobiol Dis. 2009 Jul;35(1):75-81. Epub 2009 Apr 18.
DOI Direct Link |
Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia.
We previously demonstrated that herpes simplex virus type 1 (HSV-1)... | 9th September, 2009
| University of California at San Francisco, 94143-0412, USA.
| J Virol. 2009 Aug;83(16):7873-82. Epub 2009 Jun 3.
DOI Direct Link |
Regulation of amino acid transporters in the rat remnant kidney.
BACKGROUND: Partial renal ablation is associated with compensatory renal... | 25th August, 2009
| Institute of Pharmacology and Therapeutics, Faculty of Medicine, 4200-319
| Nephrol Dial Transplant. 2009 Jul;24(7):2058-67. Epub 2009 Jan 20.
DOI Direct Link |
→View more research publications. |
LAT2 results (if any) from reagent suppliers | 
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LAT2 (P-21) Antibody sc-133726
rabbit polyclonal IgG, 100µg/ml; recommended for detection of LAT2 of m, r, ... Western blot analysis of LAT2 expression in Hep G2 whole cell lysate. ...
http://www.scbt.com/datasheet-133726-lat2-p-21-antibody.html...
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Purified Anti-Cbl Antibody - BioLegend
Interaction: NCK, CD2AP, SLA, SLA2, EGFR, SYK, LAT2 and ZAP70. Bioactivity/ Activities: E3 ubiquitin (Ub) ligases, and negative regulators of PTKs. Antigen
...
http://www.biolegend.com/purified-anti-cbl-antibody-4377.htm...
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LAT2 (G-19) Antibody sc-27581
goat polyclonal IgG, 200 µg/ml; epitope mapping within an internal region of LAT2 of human origin; recommended for detection of LAT2 of m, r and h origin by
...
http://www.scbt.com/datasheet-27581-lat2-g-19-antibody.html...
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Prestige Antibodies®
Anti-LAT2 rabbit affinity isolated antibody. LAT2, human human. IHC (p). PA. HPA003462-100UL. Anti-MBNL3 rabbit affinity isolated antibody. MBNL3, human ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/General_...
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LAT2 siRNA (m) sc-146657
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: LAT2 ...
http://www.scbt.com/ja/datasheet-146657-lat2-sirna-m.html...
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NTAL/LAB Antibody
NTAL/LAB is also known as LAT2 (linker for activation of T cells 2), WBSCR5, WBS15, WBSCR15 (Wil- liams-Beuren syndrome chromosome region 15 protein). It ...
http://www.cellsignal.com/pdf/9533.pdf...
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LAT1 (Q-20) Antibody sc-54229
home » Signaling Intermediates » LAT2 Antibody / LAT2 Antibodies » LAT1 (Q-20): sc-54229 ... Additional LAT2 Antibodies . ...
http://www.scbt.com/datasheet-54229-lat1-q-20-antibody.html...
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