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WT1


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Symbol:WT1
Name(s):Wilms tumor 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:GUD, WAGR, WIT-2, WT33
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18064689 In pleural malignant effusion, malignant mesothelioma can be identified with positive staining for WT-1 and negative staining for p63.
15150775 Observational study of gene-disease association. (HuGE Navigator)
15253707 Observational study of gene-disease association. (HuGE Navigator)
15266301 Observational study of gene-disease association. (HuGE Navigator)
15483024 Observational study of genotype prevalence and gene-disease association. (HuGE Navigator)
15687485 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
15838390 Observational study of gene-disease association. (HuGE Navigator)
16909243 Observational study of genotype prevalence. (HuGE Navigator)
17371932 Observational study of genotype prevalence. (HuGE Navigator)
18058136 Observational study of genotype prevalence. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDapoptosis response proteinWilms tumor 1 isoform D--Pubmed
HPRDp53Wilms tumor 1 isoform D--Pubmed
HPRDtumor protein p53WT1--Pubmed
HPRDubiquitin-conjugating enzyme E2IWilms tumor 1 isoform D--Pubmed
HPRDWT1U2 small nuclear RNA auxiliary factor 2 isoform a--Pubmed
HPRDWilms tumor 1 isoform DU2AF65--Pubmed
HPRDWilms tumor 1 isoform DWD repeat domain 39--Pubmed
HPRDWilms tumor 1 isoform DWilms' tumour 1-associating protein isoform 1--Pubmed
HPRDWilms tumor 1 isoform DWilms' tumour 1-associating protein isoform 1--Pubmed

Recent Publications on WT1:

Pubmed Logo
Adequate use of allele frequencies in Hispanics-a problem elucidated in nephrotic syndrome.
Previous studies in children with focal segmental glomerulosclerosis...
31st October, 2009
Departments of Pediatrics and of Human Genetics, University of Michigan, Pediatr Nephrol. 2009 Oct 30.
DOI Direct Link
Characterisation of ATRX, DMRT1, DMRT7 and WT1 in the platypus (Ornithorhynchus anatinus).
One of the most puzzling aspects of monotreme reproductive biology is how...
31st October, 2009
Discipline of Genetics, School of Molecular and Biomedical Science, Reprod Fertil Dev. 2009;21(8):985-91.
DOI Direct Link
[Immunotherapy and cell therapy]
To develop effective cellular immunotherapy for hematopoietic...
29th October, 2009
Department of Bioregulatory Medicine, Ehime University Graduate School of Nippon Rinsho. 2009 Oct;67(10):1938-43.
[Biological markers of myeloid leukemia]
There are several important biological markers in myeloid leukemia. In...
29th October, 2009
Laboratory Medicine, Hamamatsu University School of Medicine. Nippon Rinsho. 2009 Oct;67(10):1916-20.
Combination of MUC5ac and WT-1 immunohistochemistry is useful in distinguishing pancreatic ductal carcinoma from ovarian serous carcinoma in effusion cytology.
Malignant ascites may be the first presentation of an unsuspected cancer....
27th October, 2009
Department of Pathology, Wayne State University and Karmanos Cancer Diagn Cytopathol. 2009 Oct 23.
DOI Direct Link

View more research publications.

Press Releases on WT1:

BioPortfolio Logo
Ipsogen Announces the CE Marking of its "ProfileQuant(R) WT1" Kit 16th March, 2009

MARSEILLE, France, March 16 /PRNewswire/ -- IPSOGEN SA (Alternext - FR0010626028 - ALIPS), a molecular diagnostic company specialized in the development, manufacturing and commercialization of

Ganymed Announces License Of Wt1 Immunotherapy Rights By Corixa And Kirin 1st January, 1970 Ganymed

BioNews Results for WT1

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BioPortfolio Logo
Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies
Leukemia:  Oct 22 2009 2:37PM Matching: wt1

Clinical Trials:

Clinical Trials Logo
Wilm's Tumor 1 Protein Vaccine to Treat Cancers of the Blood

Patents:

Patents logo
US Patent No.Title
7547551 Transfection of eukaryontic cells with linear polynucleotides by electroporation
7567502 Methods and apparatus for adjusting bandwidth allocation in a wireless communications system
7567791 Wireless terminal methods and apparatus for use in a wireless communications system that uses a multi-mode base station
7569349 Methods for selecting monoclonal antibody therapies using extracellular DNA
7569350 Methods for selecting cancer vaccine therapies using extracellular DNA

View more patents.

WT1 results (if any) from reagent suppliers

Google CSE Logo
WT1 Antibody / WT1 Antibodies
WT1 Antibody / WT1 Antibodies. ... WT1 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-wt1.html...

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WT1 monoclonal antibody (M01)
WT1 (NP_000369, 349 a.a. ~ 439 a.a) full length recombinant protein with GST tag . ... WT1 monoclonal antibody (M01), clone 2H4 Western Blot analysis of WT1 ...
http://www.abgent.com/products/catalog_no/AT4545a_WT1_monocl...

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WT1 (C-19) Antibody sc-192
Dynamic interaction between WT1 and BASP1 in transcriptional regulation ... The Wilms' tumor suppressor WT1 is associated with melanoma proliferation. ...
http://www.scbt.com/datasheet-192-wt1-c-19-antibody.html...

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WT1 (Wilms' Tumor)
WT1 is a gene involved in the induction of Wilms' Tumor. The WT1 gene, located on ... In normal tissues, WT1 (mRNA) has been observed in human ...
http://www.biocare.net/antibody-datasheets/258.pdf...

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WT1 (F-6) Antibody sc-7385
See how others have used WT1 (F-6): sc-7385 antibody and or WT1 (F-6) ... WT1- p53 interactions in insulin-like growth factor-I receptor gene regulation. ...
http://www.scbt.com/datasheet-7385-wt1-f-6-antibody.html...

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Wilm's Tumor Protein. Mouse Monoclonal Antibody WLM04 , Human
mice immunized with recombinant human WT1 protein corresponding to amino acids 1 -318 and mouse myeloma NS1 cells. IMMUNOGEN. SPECIES REACTIVITY ...
http://www.exalpha.com/pdfs/X1480M.pdf...

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WT1 (6F-H17) Antibody sc-81619
WT1 shRNA (h) Lentiviral Particles, sc-36846-V, 200 µl ... WT1 (6F-H17): sc- 81619. Western blot analysis of WT1 expression in K-562 (A) and MOLT-4 (B) whole
...
http://www.scbt.com/datasheet-81619-wt1-6f-h17-antibody.html...

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