Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

XBP1


Suggest Content
Advertise Here
Gene DB Home
Symbol:XBP1
Name(s):X-box binding protein 1
Type:protein-coding
Organism:Homo sapiens
Synonyms:TREB5, XBP2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17906960 When islets were cultured for 24 h at 11.1 mmol/l glucose, there was induction of BiP and XBP-1 in type 2 diabetes islets but not in non-diabetic islets.
18192112 that transcription factors Xbp-1, Blimp-1, and PAX-5-encoded BSAP play important roles in the regulation of plasmacytic differentiation and exert their effects on differentiation induced by low 2ME2 concentrations
15184063 Observational study of gene-disease association. (HuGE Navigator)
15298659 Observational study of gene-disease association. (HuGE Navigator)
15331160 Observational study of gene-disease association. (HuGE Navigator)
15380296 Observational study of gene-disease association. (HuGE Navigator)
15892135 Observational study of gene-disease association. (HuGE Navigator)
15927087 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15936534 Observational study of gene-disease association. (HuGE Navigator)
16154272 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDestrogen receptor 1X box-binding protein spliced form--Pubmed
HPRDestrogen receptor 1X box-binding protein spliced form--Pubmed
BINDestrogen receptor alpha isoform 1Homo sapiens chromosome 22ER interacts with XBP-1 enhancer.-Pubmed
HPRDv-fos FBJ murine osteosarcoma viral oncogene homologX box-binding protein spliced form--Pubmed
HPRDv-fos FBJ murine osteosarcoma viral oncogene homologX box-binding protein spliced form--Pubmed
BINDforkhead box A1Homo sapiens chromosome 22FOXA1 interacts with XBP-1 enhancer.-Pubmed
BINDDNA directed RNA polymerase II polypeptide AHomo sapiens chromosome 22PolII interacts with XBP-1 enhancer.-Pubmed

Recent Publications on XBP1:

Pubmed Logo
Evidence that endoplasmic reticulum (ER) stress and caspase-4 activation occur in human neutrophils.
Apoptosis can result from activation of three major pathways: the...
3rd November, 2009
Laboratoire de recherche en inflammation et physiologie des granulocytes, Biochem Biophys Res Commun. 2009 Oct 28.
DOI Direct Link
Effect of dietary fat to produce non-alcoholic fatty liver in the rat.
BACKGROUND AND AIM: Non-alcoholic steatohepatitis (NASH) belongs to a...
3rd November, 2009
Physiology M311, School of Biomedical, Biomolecular and Chemical Sciences, J Gastroenterol Hepatol. 2009 Aug;24(8):1463-71.
DOI Direct Link
Activation and clinical significance of the unfolded protein response in breast cancer.
Introduction:The tumour microenvironment is hypoglycaemic, hypoxic and...
29th October, 2009
Academic Unit of Surgical Oncology, Department of Oncology, School of Br J Cancer. 2009 Oct 27.
DOI Direct Link
From sugar to fat: How the transcription factor XBP1 regulates hepatic lipogenesis.
Lipogenesis occurs primarily in the liver, where dietary carbohydrates...
24th October, 2009
Department of Immunology and Infectious Diseases, Harvard School of Public Ann N Y Acad Sci. 2009 Sep;1173 Suppl 1:E2-9.
DOI Direct Link
Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.
BACKGROUND: Chronic lymphocytic leukemia (CLL) is an incurable disease...
23rd October, 2009
Ghent University Hospital, Department of Hematology, De Pintelaan 185, Anticancer Res. 2009 Oct;29(10):3797-805.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611838 Biologically-active DNA-binding sites and related methods
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7171311 Methods of assigning treatment to breast cancer patients
7125839 Anti-pathogen treatments
7033781 Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating

View more patents.

XBP1 results (if any) from reagent suppliers

Google CSE Logo
XBP1 antibody (ab37151) | Abcam
See below for XBP1 antibody images, references, products related to ab37151 and other tools. ... Contact Abcam with a Technical Enquiry about XBP1 antibody ...
http://www.abcam.com/XBP1-antibody-ab37151.html...

Thumbshot
XBP-1 (M-186) Antibody sc-7160
See how others have used XBP-1 (M-186): sc-7160 antibody and or XBP-1 ... Western blot analysis of XBP-1 expression in non-transfected: sc-110760 (A) and
...
http://www.scbt.com/datasheet-7160-xbp-1-m-186-antibody.html...

Thumbshot
XBP-1 Antibody (CT) An ER signaling protein of the unfolded ...
XBP-1 antibody can be used for the detection of XBP-1 by Western blot at 0.5 - 1 ug/ml.,
http://www.prosci-inc.com/shop/catalog1/XBP-1-Antibody-p-636...

Thumbshot
The Abcam catalog
XBP1 antibodies. ... XBP1 antibody [XBP1H6E5]. WB, Dot. Mouse monoclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=137291&pt=1&c=3579...

Thumbshot
Purified Anti-Xbp-1 COOH Terminus Antibody - BioLegend
Purified Anti-Xbp-1 COOH Terminus Antibody - Xbp-1 (X-box binding protein 1) is a ubiquitously expressed 29 kD member of the CREB/ATF transcription factor ...
http://www.biolegend.com/purified-anti-xbp-1-cooh-terminus-a...

Thumbshot
XBP-1 Monoclonal Antibody X box binding protein 1
XBP-1 Monoclonal Antibody, Clone (3H1G4) from ProSci Incorporated,
http://www.prosci-inc.com/shop/catalog1/XBP-1-Monoclonal-Ant...

Thumbshot
Anti-XBP1 Polyclonal Antibody
Polyclonal Antibody against XBP1 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

Thumbshot

Search Bioportfolio and other Life Science Sites for XBP1, or search for XBP1 on BioPortfolio's antibody search engine.
This page has been viewed 433 times
Recent Search Terms used to find this page:
spliced xbp1 protein | XBP1 | XBP-1 patent | x-box xbp-1 | antibody XBP-1 spliced | xbp-1 patent | XBP1 flavivirus | spliced xbp antibody | xbp 1 monoclonal antibody | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.