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XDH
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18300946 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17622935 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17301077 |
findings show that mutation of two amino acid residues in the active site of XOR for purine substrates results in conversion of the substrate preference to aldehyde oxidase type |
| 17622935 |
These results suggest that polymorphisms -337GA and 565+64CT of XDH gene are related with blood pressure and oxidative stress in hypertension, adding evidence to the role of xanthine oxidoreductase and oxidative stress in blood pressure. |
| 12637268 |
the molybdenum center of XOR is posttranslationally inactivated by oxygen metabolites in "normal" (21% O2) cell culture atmosphere and this inactivation is reversed in hypoxia and accounts for the apparent induction. |
| 12774669 |
The activity of XO was determined in lymphocytes, eosinophils and blood serum in patients with bronchial asthma. |
| 15451061 |
XOR is expressed primarily in hepatocytes, but is also present in bile duct epithelial cells and is secreted into bile. Its role in bile is unknown but it may be involved in innate immunity of the bowel muscosa. |
| 16758302 |
The results of this study revealed that, MPO, XO and SOD conditions in gastric mucosa alone were not affected from HP presence. That's why MPO, XO, and SOD may not have important roles in the pathogenesis of HP related gastric disease in children. |
| 17523077 |
The role of conjunctival epithelial cell XO in oxidative reactions on the ocular surface of dry eye patients with Sjogren's syndrome was studied. |
| 12168784 |
XDH may play a role in generating reactive oxygen species in oxidative eye injury | →View more information from publications. |
Recent Publications on XDH: |  |
A single amino acid change (Y318F) in the L-arabitol dehydrogenase (LadA) from Aspergillus niger results in a significant increase in affinity for D-sorbitol.
BACKGROUND: L-arabitol dehydrogenase (LAD) and xylitol dehydrogenase (XDH)... | 15th September, 2009
| Department of Crystal and Structural Chemistry, Utrecht University,
| BMC Microbiol. 2009 Aug 12;9:166.
DOI Direct Link |
Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.
There is some evidence that oxidative stress plays a role in lead-induced... | 9th September, 2009
| Department of Health ad Human Services, Division of Cancer Epidemiology
| Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1841-8.
DOI Direct Link |
Engineering of a matched pair of xylose reductase and xylitol dehydrogenase for xylose fermentation by Saccharomyces cerevisiae.
Metabolic engineering of Saccharomyces cerevisiae for xylose fermentation... | 8th September, 2009
| Institute of Biotechnology and Biochemical Engineering, Graz University of
| Biotechnol J. 2009 May;4(5):684-94.
DOI Direct Link |
Formation of xanthine and the use of purine metabolites as a nitrogen source in Arabidopsis plants.
In our recent paper in The Plant Journal,1 we described the remobilization... | 26th August, 2009
| The Jacob Blaustein Institutes for Desert Research; The Albert Katz
| Plant Signal Behav. 2008 Nov;3(11):999-1001.
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Estradiol decreases xanthine dehydrogenase enzyme activity and protein expression in non-tumorigenic and malignant human mammary epithelial cells.
The retinoic acid deficiency in breast tumour epithelial cells has been... | 21st August, 2009
| Department of Experimental Oncology and Clinical Applications, University
| J Cell Biochem. 2009 Oct 15;108(3):688-92.
DOI Direct Link |
→View more research publications. |
XDH results (if any) from reagent suppliers | 
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Xanthine Oxidase (H-110) Antibody sc-20991
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XDH, 7498, 2p23.1, NM_000379 ...
http://www.scbt.com/datasheet-20991-xanthine-oxidase-h-110-a...
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Uric Acid in Cell Culture - uses of uric acid (urate) precursors ...
XDH normally functions as a dehydrogenase, but low oxygen conditions and calcium can ... XDH oxidizes hypoxanthine and xanthine to uric acid and NADH. ...
http://www.sigmaaldrich.com/life-science/cell-culture/learni...
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Xanthine Oxidase Antibody / Xanthine Oxidase Antibodies
Xanthine Oxidase Antibody / Xanthine Oxidase Antibodies.
http://www.scbt.com/table-xanthine_oxidase.html...
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A8003 Allopurinol
mp, >300 °C(lit.) Gene Information, human ... XDH(7498). Safety. Personal Protective Equipment, Eyeshields, Faceshields, Gloves, type P2 (EN 143)
respirator ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A800...
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