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XPA


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Gene DB Home
Symbol:XPA
Name(s):xeroderma pigmentosum, complementation group A
Type:protein-coding
Organism:Homo sapiens
Synonyms:XP1, XPAC
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18204222 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
15746040 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15837542 Observational study of gene-disease association. (HuGE Navigator)
16195237 Observational study of gene-disease association. (HuGE Navigator)
16284373 Observational study of gene-disease association. (HuGE Navigator)
16393248 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
16507781 Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
16613913 Observational study of gene-disease association. (HuGE Navigator)
16905156 Observational study of genotype prevalence. (HuGE Navigator)
16979838 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDexcision repair cross-complementing 1 isoform 1xeroderma pigmentosum, complementation group A--Pubmed
HPRDexcision repair cross-complementing 1 isoform 1xeroderma pigmentosum, complementation group A--Pubmed
HPRDERCC6xeroderma pigmentosum, complementation group A--Pubmed
HPRDexcision repair cross-complementing rodent repair deficiency, complementation group 6Xeroderma pigmentosum group A complementing protein--Pubmed
HPRDreplication protein A1, 70kDaxeroderma pigmentosum, complementation group A--Pubmed
HPRDreplication protein A1, 70kDaxeroderma pigmentosum, complementation group A--Pubmed
HPRDreplication protein A2, 32kDaxeroderma pigmentosum, complementation group A--Pubmed
HPRDreplication protein A2, 32kDaxeroderma pigmentosum, complementation group A--Pubmed
HPRDxeroderma pigmentosum, complementation group AXPA binding protein 1--Pubmed
HPRDxeroderma pigmentosum, complementation group AXPA binding protein 1--Pubmed

Recent Publications on XPA:

Pubmed Logo
Nucleotide excision repair genes are expressed at low levels and are not detectably inducible in Caenorhabditis elegans somatic tissues, but their function is required for normal adult life after UVC exposure.
We performed experiments to characterize the inducibility of nucleotide...
3rd November, 2009
Biomolecular Screening Branch, National Toxicology Program, National Mutat Res. 2009 Oct 29.
DOI Direct Link
Modulation of nucleotide excision repair in human lymphocytes by genetic and dietary factors.
Gene-environment interactions determine inter-individual variations in...
3rd November, 2009
Department of Health Risk Analysis and Toxicology, Nutrition and Br J Nutr. 2009 Nov 2:1-12.
DOI Direct Link
Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.
The carcinogenic potential of chemicals and pharmaceuticals is...
27th October, 2009
MicroArray Department and Integrative Bioinformatics Unit, Swammerdam Carcinogenesis. 2009 Oct;30(10):1805-12. Epub 2009 Aug 20.
DOI Direct Link
Genomic Instability and DNA Damage Responses in Progeria Arising from Defective Maturation of Prelamin A.
Progeria syndromes have in common a premature aging phenotype and...
24th October, 2009
Department of Biochemistry & Molecular Biology, Quillen College of Aging. 2009 Jan 1;1(1):28-37.
An aphidicolin-block nucleotide excision repair assay measuring DNA incision and repair capacity.
The objective of the present study was to develop a cellular phenotype...
22nd October, 2009
Laboratory of Cell Genetics, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Mutagenesis. 2009 Oct 20.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7060811 WWOX: a tumor suppressor gene mutated in multiple cancers
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7209214 Lithographic apparatus focus test method and system, and device manufacturing method
7223388 Modified reoviral therapy
7235358 Methods and compositions for diagnosing and monitoring transplant rejection

View more patents.

XPA results (if any) from reagent suppliers

Google CSE Logo
XPA antibody [5A2] (ab44) | Abcam
Mouse monoclonal [5A2] to XPA. The XPA (xeroderma pigmentosum group A) protein specifically recognizes the UV- or chemically damaged DNA lesions, ...
http://www.abcam.com/XPA-antibody-5A2-ab44.html...

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XPA Antibody / XPA Antibodies
XPA Antibody / XPA Antibodies. ... XPA specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-xpa.html...

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XPA IHC Antibody Bethyl Laboratories
Mutations in XPA (xeroderma pigmentosum group A-complementing protein) are the cause of xeroderma pigmentosum A (XP-A), an autosomal recessive disease that ...
http://www.bethyl.com/go/?product/IHC-00344...

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XPA (FL-273) Antibody sc-853
See how others have used XPA (FL-273): sc-853 antibody and or XPA ... ATR- dependent checkpoint modulates XPA nuclear import in response to UV irradiation.
...
http://www.scbt.com/datasheet-853-xpa-fl-273-antibody.html...

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Antibody Products - Protein and Antibody Solutions Provider - GenWay
20-272-193477, XPA [12F5] Related Product Names: - XPA; 7507; XPA; 278700; ... Mouse monoclonal [12F5] to XPA ; 7507; XPA; 278700; P23025; XP1; XPAC;; ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=X...

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XPA (SPM326) Antibody sc-56497
mouse monoclonal IgG2a, 200µg/ml; raised against recombinant XPA protein of human ... Western blot analysis of XPA expression in GM637 whole cell lysate.
...
http://www.scbt.com/datasheet-56497-xpa-spm326-antibody.html...

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Antibodies to DNA Repair Proteins
X1254, Anti-XPA (C-terminal) antibody produced in rabbit, IgG fraction of antiserum, mouse ... Xpa(22590) rat ... Xpa(298074) human ... XPA(7507) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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