Wednesday November 25 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

XPNPEP2


Suggest Content
Advertise Here
Gene DB Home
Symbol:XPNPEP2
Name(s):X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18158172 Increase in aminopeptidase P levels brought on by androgens could contribute to a more effective control of the kinin accumulation considered to be responsible for the symptoms of angioedema.
16175507 Observational study of gene-disease association. (HuGE Navigator)
17003818 We found significantly decreased plasma aminopeptidase P activity (P=0.013) in hypersensitivity reactions (HSR+) subjects as well as altered degradation of endogenous des-Arginine(9)-bradykinin.

Recent Publications on XPNPEP2:

Pubmed Logo
Genetic analysis of Factor XII and bradykinin catabolic enzymes in a family with estrogen-dependent inherited angioedema.
BACKGROUND: Recent studies reported a gain-of-function mutation in the...
23rd April, 2009
Centre for Excellence in Neuromics, University of Montreal, and the Centre J Allergy Clin Immunol. 2009 Apr;123(4):906-10.
DOI Direct Link
Multi-institutional phase II study of S-1 monotherapy in advanced gastric cancer with pharmacokinetic and pharmacogenomic evaluations.
This study describes the first phase II study of S-1, a novel oral...
6th December, 2007
Yonsei University College of Medicine, Seodaemun-Ku, CPO Box 8044, Seoul, Oncologist. 2007 May;12(5):543-54.
DOI Direct Link
Neuropeptide Y (NPY) cleaving enzymes: structural and functional homologues of dipeptidyl peptidase 4.
N-terminal truncation of NPY has important physiological consequences,...
14th April, 2007
Department of Functional and Applied Anatomy, Hannover Medical School, OE Peptides. 2007 Feb;28(2):257-68. Epub 2007 Jan 16.
DOI Direct Link
Kinin-dependent hypersensitivity reactions in hemodialysis: metabolic and genetic factors.
Although the association of angiotensin I-converting enzyme inhibitors...
9th January, 2007
Faculte de Pharmacie, Universite de Montreal, Universite de Montreal, Kidney Int. 2006 Nov;70(10):1823-31. Epub 2006 Sep 27.
DOI Direct Link
A variant in XPNPEP2 is associated with angioedema induced by angiotensin I-converting enzyme inhibitors.
Angiotensin I-converting enzyme inhibitors (ACEi), which are used to treat...
16th November, 2005
Centre de recherche du CHUM, Hopital Notre-Dame, Montreal, Quebec, Canada. Am J Hum Genet. 2005 Oct;77(4):617-26. Epub 2005 Sep 1.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6887679 Methods for identifying contraindications to angiotensin converting enzyme inhibitor and/or vasopeptidase inhibitor treatment
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7229969 Combinations of enzyme inhibitors and the use thereof
7273718 Isolated genomic polynucleotide fragments from chromosome 10q25.3 that encode human soluble aminopeptidase P

View more patents.

XPNPEP2 results (if any) from reagent suppliers

Google CSE Logo
Aminopeptidase P2 (T-13) Antibody sc-131383
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XPNPEP2, 7512, Xq25, O43895 ...
http://www.scbt.com/datasheet-131383-aminopeptidase-p2-t-13-...

Thumbshot
Cell Biology FOCUS
Aminopeptidase P2/XPNPEP2. 2490-ZN-010. 2494-ZN-010. None. Methionine Aminopeptidase 1/METAP1 3537-ZN-010. None. Methionine Aminpeptidase 2/METAP2 ...
http://www.rndsystems.com/DAM_public/5976.pdf...

Thumbshot
Aminopeptidase Antibody / Aminopeptidase Antibodies
Aminopeptidase Antibody / Aminopeptidase Antibodies.
http://www.scbt.com/ko/table-aminopeptidase.html...

Thumbshot
2007 Addendum_No prices.indd
Aminopeptidase P2/XPNPEP2. Mouse. Goat IgG. BAF2494. 50 µg. Angiopoietin-like 4. Human. Goat IgG. BAF3485. 50 µg. Apolipoprotein B. Human. Goat IgG. BAF3556 ...
http://www.rndsystems.com/DAM_public/5946.pdf...

Thumbshot
Aminopeptidase P2 (E-12) Antibody sc-131381
Humano, XPNPEP2, 7512, Xq25, O43895 · 300145. camundongo, Xpnpep2, 170745, X A4, NP_573476, N/A. Informacoes sobre ordens ...
http://www.scbt.com/pt/datasheet-131381-aminopeptidase-p2-e-...

Thumbshot
Quantikine® Human Pentraxin 3 ELISA
Aminopeptidase P2/XPNPEP2*. Human. 391131. MAB24901. 100 µg. Apolipoprotein E. Human. 395004. MAB41441. 100 µg. ATM. Human. 245403. MAB2290. 100 µg. BMI-1 ...
http://www.rndsystems.com/DAM_public/5959.pdf...

Thumbshot
Aminopeptidase P2 (E-12) Antibody sc-131381
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, XPNPEP2, 7512,
Xq25 ...
http://www.scbt.com/it/datasheet-131381-aminopeptidase-p2-e-...

Thumbshot

Search Bioportfolio and other Life Science Sites for XPNPEP2, or search for XPNPEP2 on BioPortfolio's antibody search engine.
This page has been viewed 80 times
Recent Search Terms used to find this page: .


Resources from the
NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.