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XRCC3


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Symbol:XRCC3
Name(s):X-ray repair complementing defective repair in Chinese hamster cells 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18204928 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18270339 Observational study and meta-analysis of gene-disease association. (HuGE Navigator)
18300452 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18330515 Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
18335219 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18336773 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18033323 patients heterozygous for the XRCC3 Thr241Met allele had improved post-induction disease-free survival compared to children homozygous for the major or minor allele
17901044 Variation in DNA repair genes XRCC3, XRCC4, XRCC5 and susceptibility to myeloma.
11059748 Observational study of gene-disease association. (HuGE Navigator)
11285194 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDRAD51 homolog C isoform 1X-ray repair cross complementing protein 3--Pubmed
HPRDRAD51 homolog C isoform 1X-ray repair cross complementing protein 3--Pubmed
HPRDDNA repair protein RAD51 homolog 4X-ray repair cross complementing protein 3--Pubmed
HPRDRAD51-like 3 isoform 1XRCC3--Pubmed

Recent Publications on XRCC3:

Pubmed Logo
Specific targeted gene repair using single-stranded DNA oligonucleotides at an endogenous locus in mammalian cells uses homologous recombination.
The feasibility of introducing point mutations in vivo using...
27th October, 2009
The Institute for Cancer Studies, University of Sheffield, Sheffield S10 DNA Repair (Amst). 2009 Oct 23.
DOI Direct Link
Do DNA repair genes OGG1, XRCC3 and XRCC7 have an impact on susceptibility to bladder cancer in the North Indian population?
OBJECTIVE: Polymorphisms in DNA repair genes may be associated with...
10th October, 2009
Department of Urology and Renal Transplantation, Sanjay Gandhi Post Mutat Res. 2009 Oct 6.
DOI Direct Link
XRCC3 Thr241Met polymorphism and breast cancer risk: a meta-analysis.
XRCC3 (X-ray repair complementing defective repair in Chinese hamster...
1st October, 2009
School of Medicine, National University of Athens, Athens, Greece, Breast Cancer Res Treat. 2009 Sep 30.
DOI Direct Link
Cellular redistribution of Rad51 in response to DNA damage: A novel role for Rad51C.
Exposure of cells to DNA damaging agents results in a rapid increase in...
29th September, 2009
UMass Medical School, United States. J Biol Chem. 2009 Sep 26.
DOI Direct Link
XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.
Sister chromatid recombination (SCR) is a potentially error-free pathway...
26th September, 2009
Department of Medicine, Harvard Medical School and Beth Israel Deaconess Mol Cell Biol. 2009 Aug;29(15):4283-94. Epub 2009 May 26.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
DNA Repair Genes and Outcomes in Patients With Stage III NSCLC

Patents:

Patents logo
US Patent No.Title
7604995 Compositions, kits, and methods for stimulation of homologous recombination
7217807 Bioinformatically detectable group of novel HIV regulatory genes and uses thereof
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7122339 Method for generating diversity
7112405 Compositions and methods for enhancing oligonucleotide-mediated gene alteration

View more patents.

XRCC3 results (if any) from reagent suppliers

Google CSE Logo
XRCC3 antibody (ab6494) | Abcam
Rabbit polyclonal to XRCC3. The XRCC3 gene encodes a member of the RecA/Rad51- related protein family that participates in homologous recombination to ...
http://www.abcam.com/XRCC3-antibody-ab6494.html...

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XRCC3 antibody, XRCC3 Antibody, Rabbit Polyclonal Antibody
Buy quality rabbit XRCC3 antibody (interacts with human), anti-XRCC3, XRCC3 antibody, rabbit polyclonal antibody, XRCC3 Antibody, Rabbit Polyclonal Antibody
...
http://www.genwaybio.com/product_info.php?products_id=313044...

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XRCC3 (N-19) Antibody sc-5904
XRCC3 shRNA (h) Lentiviral Particles, sc-37403-V, 200 µl ... See how others have used XRCC3 (N-19): sc-5904 antibody and or XRCC3 (N-19) antibody conjugates ...
http://www.scbt.com/datasheet-5904-xrcc3-n-19-antibody.html...

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XRCC3 antibodies: Chromatin and Nuclear Signaling > DNA / RNA ...
XRCC3 antibodies. ... Image Abreview Publication. ab2368 · XRCC3 antibody. IHC-P , IP, WB, IHC-Fr. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?t=5229&pt=1&c=879&ei=&mu=ra...

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XRCC Antibody / XRCC Antibodies
XRCC3 (10F1/6) Antibody, sc-53471, mouse IgG1, FL (h), WB, IP, human. XRCC3 (E- 20) Antibody, sc-5905, goat IgG, internal (h), WB, IF, ELISA, h > m, r ...
http://www.scbt.com/table-xrcc.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
RABBIT ANTI HUMAN XRCC3; DNA repair protein XRCC3, IgG Polyclonal ... Mouse polyclonal antiserum to human XRCC3; 7517; XRCC3; 600675; O43542;; 7517; XRCC3;
...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=X...

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Antibodies to DNA Repair Proteins
X4003, Anti-XRCC3 antibody produced in rabbit, (polyclonal) ... XRCC3(7517) mouse ... Xrcc3(74335) rat ... Xrcc3(314463), rodent, human, IHC, WB, pricing
...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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