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XRCC5
| Symbol: | XRCC5 | | Name(s): | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ39089, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17904587 |
Although the different genotypes were not associated with the risk of bladder cancer, individuals not carrying the two tandem repeats allele had an increased risk of bladder cancer compared with those carrying the allele with two repeats. |
| 17901044 |
Variation in DNA repair genes XRCC3, XRCC4, XRCC5 and susceptibility to myeloma. |
| 17389609 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17355791 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) |
| 17901044 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17904587 |
Observational study of gene-disease association. (HuGE Navigator) |
| 18000863 |
Observational study of gene-disease association. (HuGE Navigator) |
| 12750264 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15680411 |
Observational study of gene-environment interaction. (HuGE Navigator) |
| 15824172 |
Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | →View more information from publications. |
Recent Publications on XRCC5: |  |
Use of phage display to isolate specific human monoclonal antibody fragments against a potential target for multiple myeloma.
INTRODUCTION: Multiple myeloma (MM), a malignancy of plasma cells,... | 17th October, 2009
| Multiple Myeloma Research Laboratory, Singapore General Hospital,
| Ann Acad Med Singapore. 2009 Jul;38(7):621-9.
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[Non-homologous DNA end joining--new proteins, new functions, new mechanisms]
Humans use primarily nonhomologous end joining (NHEJ) to repair DNA double... | 27th June, 2009
| Katedra Genetyki Molekularnej, Uniwersytet Lodzki, Lodz.
| Postepy Biochem. 2009;55(1):36-45.
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Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathways.
Genes involved in DNA repair and replication have been recently... | 20th June, 2009
| Genomics and Informatics Unit, University of Torino, Turin, Italy.
| Cancer Res. 2009 Apr 15;69(8):3390-6. Epub 2009 Apr 7.
DOI Direct Link |
Genetic variants in XRRC5 may predict development of venous thrombotic events in myeloma patients on thalidomide.
Humans use primarily nonhomologous end joining (NHEJ) to repair DNA double... | 17th June, 2009
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| Blood. 2009 May 28;113(22):5691-2.
DOI Direct Link |
[Correlation between XRCC2 and XRCC5 single nucleotide polymorphisms and drug-sensitivity of human lung cancer cells]
OBJECTIVE: To study the associations between XRCC2 and XRCC5 single... | 12th June, 2009
| Department of Thoracic Surgery, Fourth Affiliated Hospital of Hebei
| Zhonghua Yi Xue Za Zhi. 2008 Nov 25;88(43):3059-62.
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→View more research publications. |
XRCC5 results (if any) from reagent suppliers | 
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K3264 Anti-Ku80 (XRCC5) (418-439) antibody produced in rabbit ...
K3264 Anti-Ku80 (XRCC5) (418-439) antibody produced in rabbit affinity isolated antibody, buffered aqueous solution.
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=K326...
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Antibody Products - Protein and Antibody Solutions Provider - GenWay
Mouse monoclonal anti-human XRCC5 antibody; N/A; Homo sapiens X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break
...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=X...
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Antibodies to DNA Repair Proteins
K3389, Anti-Ku80 (XRCC5) (322-337) antibody produced in rabbit, affinity isolated antibody, human ... XRCC5(7520) rat ... Xrcc5(363247) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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Ku-86 (M-20) Antibody sc-1485
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, XRCC5, 7520, 2q35, NM_021141 ...
http://www.scbt.com/datasheet-1485-ku-86-m-20-antibody.html...
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DNA-PK antibody, DNA PKcs (Ab-2609) Antibody, Rabbit Polyclonal ...
Subunit: DNA-PK is a heterotrimer of PRKDC and the Ku p70-p86 (XRCC6-XRCC5) dimer. Formation of this complex may be promoted by interaction with ILF3. ...
http://www.genwaybio.com/product_info.php?products_id=210107...
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Ku-70/Ku-86 (3F247) Antibody sc-71471
Human, XRCC5, 7520, 2q35, NM_021141 · P13010 · 194364. Mouse, Xrcc6, 14375, 15 E1, P23475, N/A. Mouse, Xrcc5, 22596, 1 C3, P27641 ...
http://www.scbt.com/datasheet-71471-ku-70-ku-86-3f247-antibo...
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Purified Anti-Ku Ku-70/Ku-80 Antibody - BioLegend
Other Names: ATP-dependent DNA helicase II 70KD /80 KD subunits, Ku-70/Ku-80, Ku -70/Ku-86, G22P1/ XRCC5. Structure: Ku is a heterodimeric DNA end binding ...
http://www.biolegend.com/purified-anti-ku-ku-70-ku-80-antibo...
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