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YY1


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Symbol:YY1
Name(s):YY1 transcription factor
Type:protein-coding
Organism:Homo sapiens
Synonyms:DELTA, NF-E1, UCRBP, YIN-YANG-1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17973241 study identified the major CD30 gene promoter microsatellite binding activity as the transcription factor Yin Yang 1
17434929 Transcription factor Ying Yang 1 (YY1) indirectly regulates the C promoter-binding factor 1 (CBF1)-dependent Notch1 signaling via direct interaction with the Notch1 receptor.
17980704 YY1 and E2F1 have synergistic effect on p73 promoter activity
17925399 the transcription factor YY1 binds to and recruits HDAC3 to the lanosterol synthase promoter.
17721549 Binding of YY1 to its DNA sites in target genes requires INO80, suggesting that YY1 uses the INO80 complex not only to activate transcription but also to gain access to target promoters
17556661 a new role for YY1 as both an inducer of p53 instability in smooth muscle cells, and an indirect repressor of p21WAF1/Cip1 transcription, p21WAF1/Cip1-cdk4-cyclin D1 assembly and intimal thickening.
17549406 Our findings provide for the first time evidence for the implication of YY1 in uterine cervix carcinogenesis.
12788099 The interaction domains between YY1 and SAP30 were mapped to the C-terminal segment of YY1 (295-414) and the C-terminal 91 amino acid region of SAP30.
16769183 YY1 accelerates the binding of SNAP(c) to the proximal sequence element, its target within snRNA promoters.
15295102 YY1 regulates the transcriptional activity, acetylation, ubiquitination, and stability of p53 by inhibiting its interaction with the coactivator p300 and by enhancing its interaction with the negative regulator Mdm2.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDcyclin-dependent kinase inhibitor 2A isoform 4YY1 transcription factorYY1 interacts with p14ARF.-Pubmed
BINDcAMP responsive element binding protein 1 isoform AYY1 transcription factorYY1 interacts with CREB.-Pubmed
BINDactivating transcription factor 2YY1 transcription factorYY1 interacts with ATF-2.-Pubmed
HPRDE2F transcription factor 2YY1 transcription factor--Pubmed
HPRDE2F transcription factor 2YY1 transcription factor--Pubmed
HPRDE2F transcription factor 3YY1 transcription factor--Pubmed
HPRDE2F transcription factor 3YY1 transcription factor--Pubmed
BIND-YY1 transcription factorEED interacts with EZH2.-Pubmed
HPRDgeneral transcription factor II, i isoform 1YY1 transcription factor--Pubmed
HPRDgeneral transcription factor II, i isoform 1YY1 transcription factor--Pubmed

Recent Publications on YY1:

Pubmed Logo
beta-Arrestin1 Regulates Zebrafish Hematopoiesis through Binding to YY1 and Relieving Polycomb Group Repression.
beta-Arrestin1 is a multifunctional protein critically involved in signal...
3rd November, 2009
Laboratory of Molecular Cell Biology, Institute of Biochemistry and Cell Cell. 2009 Oct 30;139(3):535-46.
DOI Direct Link
Rituximab-Mediated Cell Signaling and Chemo/Immuno-sensitization of Drug-Resistant B-NHL Is Independent of Its Fc Functions.
PURPOSE: Rituximab [chimeric anti-CD20 monoclonal antibody], alone or...
29th October, 2009
Authors' Affiliations: Department of Microbiology, Immunology, and Clin Cancer Res. 2009 Oct 27.
DOI Direct Link
CYP2C9*1B promoter polymorphisms, in linkage with CYP2C19*2, affect phenytoin auto-induction of clearance and maintenance dose.
The commonly prescribed antiepileptic drug phenytoin has a narrow...
27th October, 2009
1 St. Jude Children's Research Hospital; J Pharmacol Exp Ther. 2009 Oct 23.
DOI Direct Link
A potent enhancer element in the 5'-UTR intron is crucial for transcriptional regulation of the human ubiquitin C gene.
Ubiquitin (Ub) plays a crucial role in almost every aspect of cellular...
27th October, 2009
Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Gene. 2009 Dec 1;448(1):88-101. Epub 2009 Sep 3.
DOI Direct Link
Transcriptional regulation of mouse mast cell protease-2 by IL-15.
Mast cells (MC) play a critical role in innate and adaptive immunity...
6th October, 2009
Research Center Borstel, Germany; J Biol Chem. 2009 Oct 1.
DOI Direct Link

View more research publications.

BioNews Results for YY1

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Cancer: Research on cancer described by scientists at Wake Forest University, Comprehensive Cancer Center
NewsRX:  Nov 14 2009 6:48AM Matching: yy1

Patents:

Patents logo
US Patent No.Title
7407988 Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
7465580 Non-cytotoxic oriP replicon
7465719 Carbamic acid compounds comprising an ester or ketone linkage as HDAC inhibitors
7468251 Compositions for detection of A target nucleic acid sequence
7469185 Primary rat hepatocyte toxicity modeling

View more patents.

YY1 results (if any) from reagent suppliers

Google CSE Logo
YY1 antibody (ab12132) | Abcam
Rabbit polyclonal to YY1. YY1 is a ubiquitously distributed transcription factor belonging to the GLI Kruppel class of zinc finger proteins.
http://www.abcam.com/YY1-antibody-ab12132.html...

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YY1 Antibody / YY1 Antibodies
YY1 Antibody / YY1 Antibodies. ... YY1 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-yy1.html...

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The Abcam catalog
YY1 antibodies. ... YY1 antibody. IHC-P, WB, ICC/IF. Images · Customer Abreviews : 2 stars (out of 5). Rabbit polyclonal ...
http://www.abcam.com/index.html?t=73455&pt=1&c=914...

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YY1 (H-10) Antibody sc-7341
Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. ... Western blot analysis of YY1 expression in non-transfected control (A) and ...
http://www.scbt.com/datasheet-7341-yy1-h-10-antibody.html...

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YY1 antibody, YY1 (YY1 transcription factor) Antibody, Rabbit ...
Buy quality rabbit YY1 antibody (interacts with human mouse rat), anti-YY1, YY1 (YY1 ... Yin and yang 1; YY-1; Delta transcription factor; NF-E1; YY1 ...
http://www.genwaybio.com/product_info.php?products_id=44610...

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YY1 (H-414) Antibody sc-1703
See how others have used YY1 (H-414): sc-1703 antibody and or YY1 (H-414) antibody ... Identification of adjacent binding sites for the YY1 and E4BP4 ...
http://www.scbt.com/datasheet-1703-yy1-h-414-antibody.html...

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YY1 Antibody (Center)
Transcriptional repressor protein YY1, Yin and yang 1, ... Western blot analysis of anti-YY1 Ctr Pab (Cat. #AP2517c) in HL60 cell lysate (lane 1) and in ...
http://www.abgent.com/products/catalog_no/AP2517c_YY1_Antibo...

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