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YWHAH


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Symbol:YWHAH
Name(s):tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
Type:protein-coding
Organism:Homo sapiens
Synonyms:YWHA1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11121172 Observational study of gene-disease association. (HuGE Navigator)
16459651 Observational study of gene-disease association. (HuGE Navigator)
17611984 Detection of only 2 (14-3-3 eta and gamma) out of 7 different isoforms in synovial fluid suggests they are specific to the site of joint inflammation
12480176 Data demonstrate that 14-3-3 proteins are colocalized with Lewy bodies in Parkinson disease, but there was no specific staining for the 14-3-3 eta subunit.
16545136 gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein
11996670 Results show that three 14-3-3 isoforms, beta, gamma and eta, are DAL-1/Protein 4.1B-binding proteins.
12176995 phosphorylation of 14-3-3 binding site of myeloid leukemia factor 1 by MADM

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDv-abl Abelson murine leukemia viral oncogene homolog 1 isoform atyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptidec-Abl interacts with 14-3-3-eta.-Pubmed
HPRDBCL2 antagonist of cell deathtyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed
HPRDBCL2-antagonist of cell death protein14-3-3 Eta--Pubmed
HPRDB-Raftyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed
HPRDv-raf murine sarcoma viral oncogene homolog B114-3-3 Eta--Pubmed
HPRDcell division cycle 25B isoform 4tyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed
HPRDcell division cycle 25B isoform 4tyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed
HPRDCDC25Ctyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed
HPRDcell division cycle 25C protein isoform a14-3-3 Eta--Pubmed
HPRDcyclin-dependent kinase inhibitor 1Btyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide--Pubmed

Recent Publications on YWHAH:

Pubmed Logo
Cytoplasmic accumulation of activated leukocyte cell adhesion molecule is a predictor of disease progression and reduced survival in oral cancer patients.
Activated leukocyte cell adhesion molecule (ALCAM) has been proposed to...
3rd April, 2009
Department of Biochemistry, Institute of Rotary Cancer Hospital, All India Int J Cancer. 2009 May 1;124(9):2098-105.
DOI Direct Link
Family-based association of YWHAH in psychotic bipolar disorder.
YWHAH is a positional and functional candidate gene for both schizophrenia...
23rd January, 2009
Department of Psychiatry, Johns Hopkins School of Medicine, Baltimore, Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):977-83.
DOI Direct Link
Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures.
BACKGROUND: Doxorubicin is considered one of the most potent established...
17th December, 2008
Department of Plastic Surgery, Burn Center, Hand surgery, Sarcoma BMC Cancer. 2008 Oct 29;8:313.
DOI Direct Link
Identification of novel nasopharyngeal carcinoma biomarkers by laser capture microdissection and proteomic analysis.
PURPOSE: To identify novel nasopharyngeal carcinoma (NPC) biomarkers by...
28th March, 2008
Key Laboratory of Cancer Proteomics of Chinese Ministry of Health and Clin Cancer Res. 2008 Jan 15;14(2):435-45.
DOI Direct Link
eIF2B and oligodendrocyte survival: where nature and nurture meet in bipolar disorder and schizophrenia?
Bipolar disorder and schizophrenia share common chromosomal susceptibility...
28th February, 2008
Schizophr Bull. 2007 Nov;33(6):1343-53. Epub 2007 Feb 27.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7250496 Bioinformatically detectable group of novel regulatory genes and uses thereof
7235358 Methods and compositions for diagnosing and monitoring transplant rejection
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7171311 Methods of assigning treatment to breast cancer patients

View more patents.

YWHAH results (if any) from reagent suppliers

Google CSE Logo
14-3-3 eta antibody (ab58073) | Abcam
14-3-3 eta (YWHAH) belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine or phosphothreonine-containi...
http://www.abcam.com/14-3-3-eta-antibody-ab58073.html...

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14-3-3 η (K-12) Antibody sc-17286
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, YWHAH, 7533, 22q12.3, NM_003405 ...
http://www.scbt.com/datasheet-17286-14-3-3-eta-k-12-antibody...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
YWHAH; YWHA1 - Protein AS1; Tyrosine 3/tryptophan 5 -monooxygenase activation protein, eta polypeptide; 14-3-3 protein eta, IgG Polyclonal IHC-P. WB ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=Y...

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14-3-3 γ (C-16) Antibody sc-731
Mouse, Ywhah, 22629, 5 B1, P68510, N/A. Ordering Information. Product Name, Catalog #, Unit, Price, Qty, Wish List. 14-3-3 γ (C-16), sc-731, 200 µg/ml, $259
...
http://www.scbt.com/datasheet-731-14-3-3-gamma-c-16-antibody...

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E1408 14-3-3 Eta histidine-tagged human recombinant, expressed in ...
Synonym: 14-3-3η, 14-3-3e, 14-3-3F, MGC93547, Ywha1, YWHAH, Tyrosine 3- monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=E140...

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pan 14-3-3 (K-19) Antibody sc-629
Mouse, Ywhah, 22629, 5 B1, P68510, N/A. Mouse, Ywhaq, 22630, 12 A1.3, P68254, N/ A. Mouse, Ywhaz, 22631, 15 B3.1, P63101 ...
http://www.scbt.com/datasheet-629-pan-14-3-3-k-19-antibody.h...

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14-3-3 γ (C-16) Antibody sc-731
Mouse, Ywhah, 22629, 5 B1, P68510, 없음. 주문정보. 제품명, 카탈로그 번호, 단위, 가격, 수량, 관심상품. 14-3-3 γ (C-16), sc-731, 200 µg/ml, $259 ...
http://www.scbt.com/ko/datasheet-731-14-3-3-gamma-c-16-antib...

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