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DDR1
| Symbol: | DDR1 | | Name(s): | discoidin domain receptor tyrosine kinase 1 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | CAK, CD167, DDR, EDDR1, MCK10, NEP, NTRK4, PTK3, PTK3A, RTK6, TRKE | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18190796 |
KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling. |
| 18270328 |
Observational study of gene-disease association. (HuGE Navigator) |
| 15213330 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17440435 |
Observational study of gene-disease association. (HuGE Navigator) |
| 17970783 |
PCA-1-DDR-1 signaling is a new important axis involved in malignant potential prostate cancer associated with hormone-refractory status. |
| 17982627 |
There are significantly higher number of invading cells in DDR1a expressing hepatocellular carcinoma cells. |
| 17440435 |
In the present study we screened for single nucleotide polymorphisms (SNPs) in the DNA from 100 schizophrenia patients. We identified mutation within exon 10 that produces the amino-acid substitution N502S in the a-d isoforms, and M475V in the e isoform. |
| 16912190 |
DDR1 signaling provides a novel target for therapeutic intervention with the prosurvival/antiapoptotic machinery of tumor cells. |
| 17704737 |
DDR1 gene may be regarded as a potential marker for some types of endometrial cancer. |
| 16507902 |
DDR1 contributes to fibroblast survival in the tissue microenvironment of idiopathic pulmonary fibrosis and its up-regulation may occur in other fibroproliferative lung diseases as well. | →View more information from publications. |
Recent Publications on DDR1: |  |
Molecular characterization of cultured adult human liver progenitor cells.
Hepatic progenitor cells hold great promise as a self-renewing cell source... | 31st October, 2009
| Max Planck Institute for Molecular Genetics, Vertebrate Genomics,
| Tissue Eng Part C Methods. 2009 Oct 29.
DOI Direct Link |
Discoidin Domain Receptor 1 on Bone Marrow-Derived Cells Promotes Macrophage Accumulation During Atherogenesis.
Rationale: We described a critical role for the discoidin domain receptor... | 17th October, 2009
| Department of Laboratory Medicine and Pathobiology, University of Toronto,
| Circ Res. 2009 Oct 15.
DOI Direct Link |
DDR1/E-cadherin complex regulates the activation of DDR1 and cell spreading.
Discoidin domain receptors (DDRs) 1 and 2, collagen receptors, regulate... | 22nd September, 2009
| Department of Physiology, Kaohsiung Medical University, Kaohsiung, Taiwan.
| Am J Physiol Cell Physiol. 2009 Aug;297(2):C419-29. Epub 2009 May 27.
DOI Direct Link |
Proteomic, functional and motif-based analysis of C-terminal Src kinase-interacting proteins.
C-terminal Src kinase (Csk) that functions as an essential negative... | 11th September, 2009
| State Key Laboratory of Molecular Biology, Institute of Biochemistry and
| Proteomics. 2009 Nov;9(21):4944-61.
DOI Direct Link |
Discoidin domain receptor 1, a tyrosine kinase receptor, is upregulated in an experimental model of remyelination and during oligodendrocyte differentiation in vitro.
The discoidin domain receptor (DDR1) is highly expressed in... | 25th August, 2009
| Unitat de Psiquiatria i Psicologia Medica, Facultat de Medicina i Ciencies
| J Mol Neurosci. 2009 May;38(1):2-11. Epub 2008 Oct 4.
DOI Direct Link |
→View more research publications. |
DDR1 results (if any) from reagent suppliers | 
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