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LAPTM5


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Gene DB Home
Symbol:LAPTM5
Name(s):lysosomal associated multispanning membrane protein 5
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC125860, MGC125861
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12886255 results suggest that loss of E3 gene expression might be a crucial event during the progression of human MM
12527926 LAPTM5 shows stage-specific expression during B cell differentiation. It may be involved in B cell malignancies.

Recent Publications on LAPTM5:

Pubmed Logo
Mouse adenovirus type 1-induced breakdown of the blood-brain barrier.
Infection with mouse adenovirus type 1 (MAV-1) results in fatal acute...
3rd October, 2009
Department of Microbiology and Immunology, University of Michigan, Ann J Virol. 2009 Sep;83(18):9398-410. Epub 2009 Jul 1.
DOI Direct Link
Lysosomal-associated protein multispanning transmembrane 5 gene (LAPTM5) is associated with spontaneous regression of neuroblastomas.
BACKGROUND: Neuroblastoma (NB) is the most frequently occurring solid...
30th September, 2009
Department of Molecular Cytogenetics, Medical Research Institute and PLoS One. 2009 Sep 29;4(9):e7099.
DOI Direct Link
Deltex1 is a target of the transcription factor NFAT that promotes T cell anergy.
The molecular process underlying T cell anergy is incompletely understood....
11th August, 2009
Graduate Institute of Microbiology and Immunology, National Yang-Ming Immunity. 2009 Jul 17;31(1):72-83.
DOI Direct Link
A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation.
Modulation of surface T cell antigen receptor (TCR) expression is an...
13th August, 2008
Laboratory for Immune Diversity, Research Center for Allergy and Immunity. 2008 Jul 18;29(1):33-43.
DOI Direct Link
Correlative gene expression and DNA methylation profiling in lung development nominate new biomarkers in lung cancer.
Although transcriptional control is key for proper lung development,...
29th July, 2008
Epigenomics AG, Kleine Prasidentstrasse 1, 10178 Berlin, Germany. Int J Biochem Cell Biol. 2008;40(8):1494-508. Epub 2007 Dec 7.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6335170 Gene expression in bladder tumors
6403316 Isolation of cDNA encoding for secreted or membranal proteins
6602667 Inflammation-associated polynucleotides
6607879 Compositions for the detection of blood cell and immunological response gene expression

View more patents.

LAPTM5 results (if any) from reagent suppliers

Google CSE Logo
LAPTM Antibody / LAPTM Antibodies
LAPTM5 siRNA (h): sc-88756. LAPTM5 shRNA Plasmid (h): sc-88756-SH. LAPTM5 shRNA (h) ... LAPTM5 shRNA (m) Lentiviral Particles: sc-146647-V ...
http://www.scbt.com/table-laptm.html...

Thumbshot
GGA3 antibody (ab10553) | Abcam
Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination. J Cell Biol 175:631-45 (2006). ...
http://www.abcam.com/GGA3-antibody-ab10553.html...

Thumbshot
LAPTM5 siRNA (m) sc-146647
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: LAPTM5 ...
http://www.scbt.com/ja/datasheet-146647-laptm5-sirna-m.html...

Thumbshot

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