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DAP3


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Symbol:DAP3
Name(s):death associated protein 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:DAP-3, DKFZp686G12159, MGC126058, MGC126059, MRP-S29, MRPS29, bMRP-10
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18227431 study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry
15179560 Observational study of gene-disease association. (HuGE Navigator)
17613536 B4GALT3, DAP3, RGS16, TMEM183A and UCK2--were significantly overexpressed in dup(1q)-positive ALLs compared with high hyperdiploid ALLs without dup(1q).
15179560 DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling
15302871 DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment
15175341 DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria
12099703 Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor
15679048 High DAP3 expression is correlated with thymoma stage
12359235 not involved in TRAIL-induced apoptosis

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDAryl hydrocarbon receptordeath-associated protein 3--Pubmed
HPRDaryl hydrocarbon receptorDeath associated protein 3--Pubmed
HPRDandrogen receptor isoform 1death-associated protein 3--Pubmed
HPRDandrogen receptor isoform 1death-associated protein 3--Pubmed
HPRDnuclear receptor subfamily 3, group C, member 1 isoform alphadeath-associated protein 3--Pubmed
HPRDnuclear receptor subfamily 3, group C, member 1 isoform alphadeath-associated protein 3--Pubmed
HPRDHypoxia inducible factor 1 alpha subunitdeath-associated protein 3--Pubmed
HPRDhypoxia-inducible factor 1, alpha subunit isoform 1Death associated protein 3--Pubmed
HPRDHSP90Adeath-associated protein 3--Pubmed
HPRDheat shock 90kDa protein 1, alphaDeath associated protein 3--Pubmed

Recent Publications on DAP3:

Pubmed Logo
IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation.
Detachment of adherent epithelial cells from the extracellular matrix...
1st August, 2009
Department of Bioresources, Hokkaido University Research Center for Cell Death Differ. 2009 Jul 31.
DOI Direct Link
Death-associated protein 3 is overexpressed in human thyroid oncocytic tumours.
BACKGROUND: The human death-associated protein 3 (hDAP3) is a GTP-binding...
9th July, 2009
INSERM, U694, Centre Hospitalier Universitaire d'Angers, Laboratoire de Br J Cancer. 2009 Jul 7;101(1):132-8. Epub 2009 Jun 16.
DOI Direct Link
hNOA1 interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis.
Mitochondria are dynamic organelles that play key roles in metabolism,...
14th April, 2009
Department of Cellular and Molecular Medicine, University of California, J Biol Chem. 2009 Feb 20;284(8):5414-24. Epub 2008 Dec 22.
DOI Direct Link
Cathepsin D protects human neuroblastoma cells from doxorubicin-induced cell death.
High incidence of chemotherapy resistance is the primary cause of...
15th October, 2008
Department of Tumor Genetics B030, Deutsches Krebsforschungszentrum, Im Carcinogenesis. 2008 Oct;29(10):1869-77. Epub 2008 Jun 19.
DOI Direct Link
Effect of positive charge in VIP 16gamma-glutamyl diamino derivatives on hVPAC1 and hVPAC2 receptor function.
Increase of VPAC receptor s binding to the (16)gamma-glutamyl...
16th April, 2008
Department of Experimental Medicine, Medical School, II University of J Pept Sci. 2008 Jan;14(1):102-9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
5336758 Peptides stimulating cytotoxic T cells immune to HIV RT
6446227 Semiconductor memory device
6746855 L-lysine-producing corynebacteria and process for the preparation of L-lysine
6777589 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof
6787161 Anti-cancer compounds

View more patents.

DAP3 results (if any) from reagent suppliers

Google CSE Logo
Anti-DAP3 Polyclonal Antibody
Polyclonal Antibody against DAP3 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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DAP-3 (10) Antibody sc-135876
Western blot analysis of DAP-3 expression in SW-13 whole cell lysate. sc-135876. DAP-3 (10): sc-135876. Immunofluorescence staining of human endothelial ...
http://www.scbt.com/datasheet-135876-dap-3-10-antibody.html...

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DAP3 antibodies: Chromatin and Nuclear Signaling > DNA / RNA ...
DAP3 antibodies. ... DAP3 antibody. WB. Goat polyclonal. Reacts with: Hu. ab13893 · DAP3 antibody. WB. Images. Rabbit polyclonal. Reacts with: ...
http://www.abcam.com/index.html?t=9378&pt=1&c=895&ei=&mu=ra...

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DAP-3 (P-16) Antibody sc-14099
DAP-3 shRNA (h) Lentiviral Particles, sc-37381-V, 200 µl ... DAP-3 (P-16): sc- 14099. Western blot analysis of DAP-3 expression in Daudi whole cell lysate. ...
http://www.scbt.com/datasheet-14099-dap-3-p-16-antibody.html...

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DAP1 Antibody
Death associated protein 3 (DAP3) is widely expressed, and the expression is upregulated during ... apoptosis, DAP3 acts as a positive mediator, functioning
...
http://www.cellsignal.com/pdf/2282.pdf...

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DAP-3 (4H75) Antibody sc-70949
DAP-3 shRNA (h) Lentiviral Particles, sc-37381-V, 200 µl ... DAP-3 (4H75): sc- 70949. Western blot analysis of DAP-3 expression in Daudi (A), HeLa (B), ...
http://www.scbt.com/datasheet-70949-dap-3-4h75-antibody.html...

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DAPK3/ZIPK Antibody
DAP3 Antibody #2172. DAP5 Antibody #2182. DAPK1 Kinase #7647. DAPK3 Kinase #7441 . Phospho-Stat3 (Ser727) (6E4) Mouse mAb #9136 ...
http://www.cellsignal.com/pdf/2928.pdf...

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