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RAB7A
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18272684 |
All tested CMT2B-associated Rab7 mutations are mechanistically similar, suggesting that activated forms of the Rab7 are responsible for CMT2B disease. |
| 17625594 |
GTP-bound form of Rab7 promotes melanogenesis through the regulation of gp100 maturation in melanoma cells. |
| 18039930 |
RIDalpha coordinates recruitment of these GTP-Rab7 effectors to compartments that would ordinarily be perceived as early endosomes, thereby promoting the degradation of selected cargo. |
| 15099588 |
All patients presented with a symmetric motor and sensory neuropathy, which was more pronounced in the lower limbs. Further, distal muscle wasting and impaired deep tendon reflexes were found.and linkage to chromosome 19q13.3. |
| 14644159 |
increase in the concentration of copper in the medium (189 microM) rapidly induces a redistribution of the MNK protein from early sorting endosomes, positive for Rab5-myc protein, to late endosomes, containing the Rab7-myc protein |
| 16176980 |
ORP1L binds to Rab7, modifies its functional cycle, and can interfere with lysosome organization and endocytic membrane trafficking. |
| 15933719 |
The crystal structure of Rab7-GTP in complex with the Rab7 binding domain of RILP reveals that Rab7 interacts with RILP specifically via two distinct areas. |
| 15340014 |
Results show a role for Rab7 in the final maturation of late autophagic vacuoles. |
| 16965270 |
Rab7 controls microtubule-mediated transport of early and Rab27a the subsequent actin-dependent transport of mature melanosomes. |
| 12850305 |
Not a new major locus for Japanese oculocutaneous albinisms. | →View more information from publications. |
Recent Publications on RAB7A: |  |
Rab GTPase regulation of VEGFR2 trafficking and signaling in endothelial cells.
OBJECTIVE: Vascular endothelial growth factor receptor 2 (VEGFR2) is a... | 16th July, 2009
| Endothelial Cell Biology Unit, Institute for Molecular & Cellular Biology,
| Arterioscler Thromb Vasc Biol. 2009 Jul;29(7):1119-24. Epub 2009 Apr 16.
DOI Direct Link |
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway.
Toll-like receptor 4 (TLR4) signals the induction of transcription factor... | 28th May, 2009
| School of Biochemistry and Immunology, Trinity College Dublin, Ireland.
| Nat Immunol. 2009 Jun;10(6):579-86. Epub 2009 May 3.
DOI Direct Link |
Cloning of two genes encoding Rab7 in Paramecium.
Rab7 is a small GTPase that plays a crucial role in the regulation of... | 12th December, 2006
| Nencki Institute of Experimental Biology, Department of Cell Biology,
| Acta Biochim Pol. 2006;53(1):149-56. Epub 2005 Dec 19.
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A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica.
Vesicular trafficking plays an important role in a virulence mechanism of... | 17th February, 2006
| Department of Parasitology, Gunma University Graduate School of Medicine,
| Mol Biol Cell. 2005 Nov;16(11):5294-303. Epub 2005 Aug 24.
DOI Direct Link |
RAB7A results (if any) from reagent suppliers | 
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Antibodies to Endosomes
Rab7(19349) human ... RAB7A(7879) rat ... Rab7a(29448), mouse, rat, human, IF (i ), WB, pricing ... Rab7a(29448), bovine, rat, mouse, human, chicken, monkey ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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R8779 Monoclonal Anti-Rab7 antibody produced in mouse ~2 mg/mL ...
isotype, IgG2b. Gene Information, human ... RAB7A(7879). rat ... Rab7a(29448). mouse ... Rab7(19349). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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Q-R
HPA006964, Anti-RAB7A antibody produced in rabbit, affinity isolated antibody, human ... RAB7A(7879), human, IHC (p), PA, WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....
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R4779 Anti-Rab7 antibody produced in rabbit affinity isolated ...
Gene Information, human ... RAB7A(7879). rat ... Rab7a(29448). mouse ... Rab7( 19349). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=R477...
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Rab Antibody / Rab Antibodies
Rab 7 (A-16) Antibody, sc-11303, goat IgG, C-terminus (h), WB, IF, ELISA, m, r, h, dog. Rab 7 (C-19) Antibody, sc-6563, goat IgG, C-terminus (h), WB, IP, ...
http://www.scbt.com/table-rab.html...
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Abstract Methods Conclusions References Affiliations
Fatty Acid. Synthase. Table 2: Neuron Specific Gene Regulation. Neuronal function. 1.8. RAB7A. Glial marker. -1.1. GFAP. Neuronal migration ...
http://www.piercenet.com/files/HughesD_ASCB_Poster2008.pdf...
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Rab 7 (C-19) Antibody sc-6563
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, RAB7A, 7879, 3q21.3, NM_004637 ...
http://www.scbt.com/datasheet-6563-rab-7-c-19-antibody.html...
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