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CALCA


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Symbol:CALCA
Name(s):calcitonin-related polypeptide alpha
Type:protein-coding
Organism:Homo sapiens
Synonyms:CALC1, CGRP, CGRP-I, CGRP1, CT, KC, MGC126648
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18211417 Significantly higher CGRP concentration was observed in atopic dermatitis patients suffering from severe pruritus.
18180663 serum procalcitonin level is a valuable marker of sepsis severity
11185743 Observational study of gene-disease association. (HuGE Navigator)
11317366 Observational study of gene-disease association. (HuGE Navigator)
14627864 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
15880427 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
17026622 Observational study of gene-disease association. (HuGE Navigator)
17485015 Observational study of gene-disease association. (HuGE Navigator)
17535749 Observational study of gene-disease association. (HuGE Navigator)
17941085 These data show that ADM acts as a survival factor in osteoblastic cells via a CGRP1 receptor-MEK-ERK pathway, which provides further understanding on the physiological function of ADM in osteoblasts.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDcalcitonin isoform CALCA preproproteincalcitonin receptorCT interacts with CTR.-Pubmed
HPRDcalcitonin isoform CALCA preproproteincalcitonin receptor-like--Pubmed
HPRDcalcitonin isoform CALCA preproproteincalcitonin receptor-like--Pubmed
HPRDcalcitonin isoform CALCA preproproteinreceptor activity-modifying protein 1 precursor--Pubmed
HPRDcalcitonin isoform CALCA preproproteinreceptor activity-modifying protein 1 precursor--Pubmed

Recent Publications on CALCA:

Pubmed Logo
[Hormones and osteoporosis update. Calcitonin, CGRP and bone]
Calcitonin is the hormone secreted from parafollicular cells in the...
23rd October, 2009
Department of Pediatrics, Osaka University Graduate School of Medicine. Clin Calcium. 2009 Jul;19(7):929-34.
DOI Direct Link
Reduced VGLUT2 expression increases motor neuron viability in Sod1(G93A) mice.
Glutamate-induced excitotoxicity has been suggested to influence...
23rd September, 2009
Department of Neuroscience, Uppsala University, Box 593, 75123 Uppsala, Neurobiol Dis. 2009 Sep 19.
DOI Direct Link
No association between CALCA polymorphisms and clinical outcome or serum procalcitonin levels in German polytrauma patients.
PURPOSE: Procalcitonin (PCT) is accepted to be a relevant prognostic...
22nd September, 2009
Trauma Department, Medical School Hannover, Carl Neuberg Strasse 1, 30625 Cytokine. 2009 Jul;47(1):30-6. Epub 2009 May 15.
DOI Direct Link
BCL2-938C>A and CALCA-1786T>C polymorphisms in aseptic loosened total hip arthroplasty.
The search for influencing factors and new pathways in aseptic loosening...
12th August, 2009
Department of Orthopaedics, University of Duisburg-Essen, Germany. Eur J Med Res. 2009 Jun 18;14(6):250-5.
Expression of adrenomedullin 2 (ADM2)/intermedin (IMD) in human placenta: role in trophoblast invasion and migration.
Calcitonin gene-related peptide (CALCB), amylin, and adrenomedullin (ADM)...
19th June, 2009
Department of Obstetrics and Gynecology, University of Texas Medical Biol Reprod. 2009 Oct;81(4):777-83. Epub 2009 Jun 17.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
A Study Comparing Oral Calcitonin to Nasal Spray Calcitonin in Postmenopausal Osteoporotic Women

Patents:

Patents logo
US Patent No.Title
7611841 Method for detecting methylation of promoter using restriction enzyme and DNA chip
5353523 Shoe with an improved midsole
5418321 Audio channel system for providing an analog signal corresponding to a sound waveform in a computer system
5514694 Peptidyl ketoamides
5851760 Method for generation of sequence sampled maps of complex genomes

View more patents.

CALCA results (if any) from reagent suppliers

Google CSE Logo
CALCA antibody, Procalcitonin Antibody, Mouse Monoclonal Antibody
Buy quality mouse CALCA antibody (interacts with n/a), anti-CALCA, Procalcitonin antibody, mouse monoclonal antibody, Procalcitonin Antibody, ...
http://www.genwaybio.com/product_info.php?products_id=240944...

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Calcitonin Antibody / Calcitonin Antibodies
CALCA shRNA Plasmid (h): sc-39277-SH. CALCA shRNA (h) Lentiviral Particles: sc- 39277-V. CALCA ... CALCA shRNA Plasmid (m): sc-39278-SH. CALCA shRNA (m) ...
http://www.scbt.com/table-calcitonin.html...

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Antibodies to Other Protein/Peptide Hormones
CALCA(796) rat ... Calca(24241), rat, human, IF (i), IHC (f), pricing .... human ... CALCA(796), canine, rat, human, ELISA (i), ICC, Neutral, RIA, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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CALCA siRNA (h) sc-39277
Click here for details. suitable control antibody: Calcitonin (F-13): sc-9174; sqRT-PCR Primer also available: CALCA (h)-PR: sc-39277-PR, 20 µl ...
http://www.scbt.com/ko/datasheet-39277-CALCA-sirna-h.html...

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Antibodies
C2355, Anti-Calcitonin antibody produced in rabbit, whole antiserum, human ... CALCA(796) rat ... Calca(24241), rat, human, IF (i), IHC (f), pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...

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Calcitonin (14C12) Antibody sc-51797
CALCA (h)-PR, sc-39277-PR, 10 µM ... CALCA shRNA Plasmid (h), sc-39277-SH, 20 µg ... CALCA shRNA (h) Lentiviral Particles, sc-39277-V, 200 µl ...
http://www.scbt.com/datasheet-51797-calcitonin-14c12-antibod...

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C2355 Anti-Calcitonin antibody produced in rabbit whole antiserum ...
indirect immunofluorescence: suitable. Gene Information, human ... CALCA(796). rat ... Calca(24241). shipped in, dry ice. storage temp. −20°C ...
https://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=C23...

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