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NEIL1


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Symbol:NEIL1
Name(s):nei endonuclease VIII-like 1 (E. coli)
Type:protein-coding
Organism:Homo sapiens
Synonyms:FLJ22402, FPG1, NEI1, hFPG1
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18032376 human DNA glycosylase NEIL1 interacts with proliferating cell nuclear antigen and may have a role in replication-associated repair of oxidized bases
18155253 Observational study of gene-disease association. (HuGE Navigator)
17556049 Centrosomal localization of hNEIL1 was observed when mitotic HeLa cells were immunostained with hNEIL1 antibodies
17611195 WRN participates in the same DNA repair pathway as NEIL1.
15232006 "zincless finger" appears to be required for NEIL1 activity, because mutating a very highly conserved arginine within this motif greatly reduces the glycosylase activity of the enzyme.
12509226 Pyrimidine dimer repair enzyme located on the long arm of chromosome 15 that is frequently deleted in human cancers.
15319300 Reduced expression of NEIL1 is associated with the pathogenesis of gastric cancers
17395641 Human NEIL1 DNA glycosylase activity is significantly stimulated by hHus1, hRad1, hRad9 separately and by the 9-1-1 complex.
14522990 NEIL1 and NEIL2 are preferentially involved in repair of lesions in DNA bubbles generated during transcription and/or replication
15533839 NEIL1 is a DNA glycosylase that excise 5-formyluracil, 5-hydroxymethyluracil and Thymine glycol in human cells.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDligase III, DNA, ATP-dependent isoform alphanei endonuclease VIII-like 1DNA Ligase III- alpha interacts with Neil1.-Pubmed
BINDpolymerase, betanei endonuclease VIII-like 1Pol beta interacts with Neil1.-Pubmed
HPRDX-ray repair cross complementing protein 1nei endonuclease VIII-like 1--Pubmed
BINDX-ray repair cross complementing protein 1nei endonuclease VIII-like 1XRCC1 interacts with Neil1.-Pubmed

NEIL1 results (if any) from reagent suppliers

Google CSE Logo
NEIL1 antibody (ab14753) | Abcam
Goat polyclonal to NEIL1. Human NEIL1 is the homologs of Escherichia coli Nei. Human NEIL1 is a DNA glycosylase, that phylogenetically belongs to the ...
http://www.abcam.com/NEIL1-antibody-ab14753.html...

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NEIL1 (S-17) Antibody sc-47611
NEIL1 shRNA (h) Lentiviral Particles, sc-61166-V, 200 µl ... Western blot analysis of NEIL1 expression in non-transfected 293: sc-110760 (A), human NEIL1
...
http://www.scbt.com/datasheet-47611-neil1-s-17-antibody.html...

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NEIL1 antibody, NEIL1 Antibody, Goat Polyclonal Antibody
Buy quality goat NEIL1 antibody (interacts with human), anti-NEIL1, NEIL1 antibody, goat polyclonal antibody, NEIL1 Antibody, Goat Polyclonal Antibody ...
http://www.genwaybio.com/product_info.php?products_id=336098...

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NEIL1 (h): 293 Lysate sc-111234
Western blot analysis of NEIL1 expression in non-transfected 293: sc-110760 (A), human NEIL1 transfected 293: sc-111234 (B) and HeLa (C) whole cell lysates. ...
http://www.scbt.com/datasheet-111234-neil1-h-293-lysate.html...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
NEIL1; - Nei endonuclease VIII-like 1; N/A, IgG Polyclonal E, Source: Goat Reactivity: Human ... 18-202-335343, NEIL1 / NEH1 Related Product Names: - NEIL1
; ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=N...

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NEIL1 siRNA (h) sc-61166
Click here for details. contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: NEIL1 (h)-PR: sc-61166-PR, 20 µl ...
http://www.scbt.com/ja/datasheet-61166-neil1-sirna-h.html...

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Abcam antibodies and reagents product map
... NEI3 antibodies (2) · NEIL1 antibodies (1) · NEIL2 antibodies (2) · NTH1 antibodies (3) · Ogg1 antibodies (6) · Ogg1 proteins and peptides (1) ...
http://www.abcam.com/index.html?c=250...

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