Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18039466 |
Hence, Nanog does not inhibit terminal differentiation of committed cells but it is an inhibitor of trans-differentiation that is dependent on de-novo activation of gene transcription. |
| 16501172 |
NANOG overexpression in human embryonic stem cells enables their propagation for multiple passages during which the cells remain pluripotent |
| 16540082 |
Nanog possesses an oncogenic potential that may be related to the role it plays in germ cell tumors and to its function in self renewal of ES cells. |
| 16923129 |
These results suggest that NANOG plays a crucial role in maintaining the pluripotent state of primate embryonic stem cells. |
| 17314394 |
reprogramming of DNA methylation and histone modifications on regulatory regions of the developmentally regulated OCT4 and NANOG genes |
| 15982323 |
NANOG is a new marker for testicular carcinoma in situ and germ cell tumours. |
| 15108323 |
mouse and human Nanog and Nanog2 genes may have a common role in the maintenance of pluripotency in both species |
| 16153702 |
The NANOG protein co-occupy a substantial portion of its target genes, and collaborate to form regulatory circuitry consisting of autoregulatory and feedforward loops. |
| 15749924 |
Gene knockdown of Nanog promotes differentiation, thereby demonstrating a role for these factors in human embryonic stem cell self-renewal. |
| 15983365 |
findings suggest that NANOG acts as a gatekeeper of pluripotency in human embryonic stem and carcinoma cells by preventing their differentiation to extraembryonic endoderm and trophectoderm lineages |
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