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DCL2


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Gene DB Home
Symbol:DCL2
Name(s):DCL2 (DICER-LIKE 2); ATP-dependent helicase/ ribonuclease III
Type:protein-coding
Organism:Arabidopsis thaliana
Synonyms:DICER-LIKE 2, T17B22.28
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17592042 Study shows that unidirectional (3-->5') transitivity requires the hierarchical and redundant functions of DCL4 and DCL2 acting downstream from RDR6 to produce 21- and 22-nt-long siRNAs, respectively.
16741077 DCL4 and DCL2 exhibit specific, hierarchical antiviral activities; inhibition of DCL4 by a viral-encoded suppressor revealed the subordinate antiviral activity of DCL2
16810317 DCL2 antagonizes the production of miRNAs and siRNAs by DCL1 in certain circumstances and can substitute for DCL4 when DCL4 activity is reduced or inhibited by viruses.

DCL2 results (if any) from reagent suppliers

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