Friday November 27 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

BAP1


Suggest Content
Advertise Here
Gene DB Home
Symbol:BAP1
Name(s):BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp686N04275, FLJ35406, FLJ37180, HUCEP-13, KIAA0272, hucep-6
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12160938 2D fingerprinting & mass spectrometry reveal specific targets of protein oxidation in Alzheimer's disease brain, including ubiquitin carboxy-terminal hydrolase L-1, suggesting involvement of oxidatively modified proteins in neurodegeneration.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDbreast cancer 1, early onset isoform 1BRCA1 associated protein-1--Pubmed
HPRDbreast cancer 1, early onset isoform 1BRCA1 associated protein-1--Pubmed

Recent Publications on BAP1:

Pubmed Logo
The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
The deubiquitinating enzyme BAP1 possesses growth inhibitory activity and...
10th October, 2009
Mayo Clinic, United States; J Biol Chem. 2009 Oct 8.
DOI Direct Link
Does botrytis cinerea Ignore H(2)O(2)-induced oxidative stress during infection? Characterization of botrytis activator protein 1.
Botrytis cinerea is a phytopathogen infecting a broad range of plants...
10th October, 2009
Institut fur Botanik, Westf. Wilhelms-Universitaet Muenster, Schlossgarten Mol Plant Microbe Interact. 2009 Aug;22(8):987-98.
DOI Direct Link
Wound Exudate as a Proteomic Window to Reveal Different Mechanisms of Tissue Damage by Snake Venom Toxins.
In light of the complexity of wound tissue, proteomic analysis may not...
22nd September, 2009
Instituto Clodomiro Picado, Facultad de Microbiologia, Universidad de J Proteome Res. 2009 Oct 7.
DOI Direct Link
Association between SNPs within candidate genes and compounds related to boar taint and reproduction.
BACKGROUND: Boar taint is an unpleasant odour and flavour of the meat from...
18th August, 2009
The Norwegian Pig Breeders Association (NORSVIN), Hamar, Norway. BMC Genet. 2009 Jul 5;10:32.
DOI Direct Link
High-resolution crystal structure of the snake venom metalloproteinase BaP1 complexed with a peptidomimetic: insight into inhibitor binding.
BaP1, a zinc-dependent endopeptidase belonging to the P-I class of snake...
14th August, 2009
Department of Pharmaceutical Biology and Biotechnology, Institute of Biochemistry. 2009 Jul 7;48(26):6166-74.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7598031 Method for the detection of gene transcripts in blood and uses thereof
6939691 E. coli and Streptomyces host cells that contain MatBC genes or E. coli host cells that contain pcc genes useful for enhanced polyketide production
6839456 System for accurately obtaining a contour and/or quantitative information from an echo image with reduced manual operation
6777192 Recombinant neospora antigens and their uses
6716423 Recombinant neospora antigens and their uses

View more patents.

BAP1 results (if any) from reagent suppliers

Google CSE Logo
BAP1 Antibody / BAP1 Antibodies
BAP1 Antibody / BAP1 Antibodies. ... BAP1 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-bap1.html...

Thumbshot
Phospho-BAP1 (Ser592) Antibody #9373
Western blot analysis of extracts from HeLa cells, untreated or UV-treated (50 mJ, 1 hour recovery), using Phospho-BAP1 (Ser592) Antibody (upper) or β-Actin
...
http://www.cellsignal.com/products/9373.html...

Thumbshot
BAP1 antibody [3c11] (ab10531) | Abcam
Mouse monoclonal [3c11] to BAP1. BRCA1 Associated Protein 1 (BAP1), a 81 kD protein encoded by the BAP1 gene that is proposed to be a tumor suppressor gene,
...
http://www.abcam.com/BAP1-antibody-3c11-ab10531.html...

Thumbshot
BAP1 (3C11) Antibody sc-13576
mouse monoclonal IgG1; 200 µg/ml; raised against full length BAP1 (BRCA1- associated protein 1) of ... Western blot analysis of BAP1 expression in A-431 (
A), ...
http://www.scbt.com/datasheet-13576-bap1-3c11-antibody.html...

Thumbshot
Phospho-BAP1 (Ser592) Antibody
rangement, deletion and null mutation of BAP1 have been found in lung and breast cancers (1,2). ... Phosphorylation of Ser592 on BAP1 was identified at Cell ...
http://www.cellsignal.com/pdf/9373.pdf...

Thumbshot
BAP1 (H-300) Antibody sc-28236
BAP1 shRNA (h) Lentiviral Particles, sc-29787-V, 200 µl ... BAP1 (H-300): sc- 28236. Western blot analysis of BAP1 expression in A-431 (A), ...
http://www.scbt.com/datasheet-28236-bap1-h-300-antibody.html...

Thumbshot
BAP1 Bethyl Laboratories
BRCA1-associated protein 1 (BAP1) functions as a C-terminal ubiquitin hydrolase and may be involved in the transduction of signals in the BRCA1 pathway.
http://www.bethyl.com/category/BAP1/Antibody/AAAAAAAAGABF...

Thumbshot

Search Bioportfolio and other Life Science Sites for BAP1, or search for BAP1 on BioPortfolio's antibody search engine.
This page has been viewed 147 times
Recent Search Terms used to find this page:
brca1 associated protein 1( bap1) | BAP1 2008 | brca1 hox protein | bap1 brca1 | BAP1 BRCA1 | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.