Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17609283 |
DCL4 is capable of accessing flexibly structured single-stranded RNA substrates (preferably T-shaped hairpins) to produce satsiRNAs. This result reveals that viral RNA of diverse structures may stimulate antiviral DCL activities in plant cells. |
| 17592042 |
Study shows that unidirectional (3-->5') transitivity requires the hierarchical and redundant functions of DCL4 and DCL2 acting downstream from RDR6 to produce 21- and 22-nt-long siRNAs, respectively. |
| 16040244 |
DCL4 is the primary processor of endogenous RDR6-dependent trans-acting siRNAs (tasiRNAs). |
| 16741077 |
DCL4 and DCL2 exhibit specific, hierarchical antiviral activities; inhibition of DCL4 by a viral-encoded suppressor revealed the subordinate antiviral activity of DCL2 |
| 17400893 |
Several gene transcripts were found to be routed through the RDR6/DCL4-dependent pathway after initial targeting by one or multiple microRNAs or trans-acting short interfering RNA. |
| 16810317 |
DCL4 is the primary producer of Cucumber mosaic virus (CMV) derived siRNAs and also produces turnip crinkle virus (TCV)-derived siRNAs. DCL2 appears to be the major producer of TCV-derived siRNAs, likely because TCV suppresses the activity of DCL4.[DCL4] |
| 16273107 |
DICER-LIKE 4 (DCL4) produces the 21-nt siRNA from the inverted repeat transgenes is the RNA component of cell-to-cell silencing signal in plants. [DCL4] |
| 16129836 |
dcl4-2 mutant resembled an RNA-dependent RNA polymerase 6 mutant in that both mutants lacked ta-small interfering RNAs [DCL4] |
