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GAI


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Symbol:GAI
Name(s):GAI (GA INSENSITIVE); transcription factor
Type:protein-coding
Organism:Arabidopsis thaliana
Synonyms:F10B6.34, F10B6_34, GA INSENSITIVE, GAI PROTEIN, RESTORATION ON GROWTH ON AMMONIA, RGA2
Links: Pubmed, Entrez Gene, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18078472 A study evaluting ethylene-giberillic acid crosstalk in gibberellin-insensitive (gai), ethylene-overproducing 2-1 (eto2-1) double mutant A. thaliana is reported.
17449805 PIL5 binds directly to GAIpromoters but not to Giberellic and Abscisic metabolic gene promoters in arabidopsis.
15155881 SLEEPY1 interacts directly with RGA and GA INSENSITIVE (GAI, a closely related DELLA protein) via their C-terminal GRAS domain
15161962 SLY1 (the wild-type form) and sly1gar2-1 both confer substrate specificity on this complex via specific binding to the DELLA proteins, GAI and RGA
16404575 Through transgenic modification, DELLA-less versions of GAI (gai) and RGL1 (rgl1) in a Populus tree have profound, dominant effects on phenotype, producing pleiotropic changes in morphology and metabolic profiles.
16034591 We show that ga1-3 seeds lacking RGA, RGL1 and RGL2 or GAI, RGL1 and RGL2, confer GA-independent germination in the light but not in the darkness whilst ga1-3 seeds lacking GAI, RGA and RGL2 germinate both in the light and darkness.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDSLY1GAISLY1 interacts with GAI.-Pubmed

Press Releases on GAI:

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AlphaRx Reports Positive Preclinical Data on GAI-122 Against Liver Disease 8th July, 2009 AlphaRx Inc.
    GAI-122, an investigational injectable nano-emulsion formulated with
    AlphaRx's proprietary drug delivery technology, provides significant
    hepatoprotection in multiple animal
        
AlphaRx and Gaia BioPharma Report Positive Efficacy Results in a Pre-Clinical Trial of GAI-122 Injectable Nano-emulsion for Post-operative Delirium 29th June, 2009 AlphaRx Inc.
    GAI-122, an investigational injectable nanoemulsion formulated with
    AlphaRx's proprietary drug delivery technology, providing significant
    neuro-protection in multiple in vitro
        
AlphaRx and Gaia BioPharma Provide GAI-122 Development Update 16th June, 2009 AlphaRx Inc.
    GAI-122, an investigational injectable nano-emulsion formulated with
    AlphaRx's proprietary drug delivery technology, provides significant
    neuroprotection in animal behavioral
        

GAI results (if any) from reagent suppliers

Google CSE Logo
[FP]2 cAMPfire™ and EnVision™: A Solution for Screening Gas- and ...
[FP]2 cAMPfireTM and EnVisionTM: A solution for screening Gαs- and. Gαi-coupled GPCRs using. PerkinElmer's new “red-shifted” fluorescence polarization assay ...
http://las.perkinelmer.com/content/relatedmaterials/posters/...

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General Antibody Information - Antibodies - Rockland ...
Antibodies - Rockland Immunochemicals online catalog of primary and secondary antibodies including conjugates and custom antibody production.
http://www.rockland-inc.com/commerce/misc/gai.jsp...

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[FP]2 cAMPfire™: A Solution for Screening Gas- and Gai-Coupled ...
PerkinElmer Life and Analytical Sciences, 710 Bridgeport Avenue, Shelton, CT USA (800) 762-4000 (+1) 203 925-4602 www.perkinelmer.com ...
http://las.perkinelmer.com/Content/RelatedMaterials/Posters/...

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Myelin Basic Protein antibody (ab49208) | Abcam
Courtesy of Dr Wei-Ping Gai, The Flinders University of South Australia. Product image Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) ...
http://www.abcam.com/Myelin-Basic-Protein-antibody-ab49208.h...

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Functional Characterization and Screening of Gai-Coupled GPCRs ...
and Screening of Gai-Coupled. GPCRs using AlphaScreen™. cAMP Detection Technology. Nathalie Bouchard, Erik Robitaille and Dean Wenham ...
http://las.perkinelmer.com/Content/RelatedMaterials/Posters/...

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ALPHA SYNUCLEIN antibody, ALPHA SYNUCLEIN Antibody, Goat ...
1. Spillantini. M.G. et al. (1997) Alpha-synuclein in Lewy bodies 2. Gai. W.P. et al. (1997) Multiple-system atrophy: a new alpha-synuclein disease. ...
http://www.genwaybio.com/product_info.php?products_id=76340...

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Anti- Purinergic Receptor P2Y13 (P0120) - Data Sheet
to the Gai class of G-proteins.1 The P2Y13 receptor is highly expressed at brain and spleen tissues as well as in the immune system. Lower expression was ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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