|
| |
EEA1
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12963735 |
activation of p38 MAPK caused a decrease in EEA1 colocalization with phagosomes, arresting maturation into the phagolysosome |
| 16331966 |
Results describe the geometry of the micelle penetration of the early endosome antigen 1 FYVE domain. |
| 16448788 |
PIKfyve is distributed in microdomains that are distinct from those occupied by EEA1 and Hrs |
| 15052657 |
macropinosomes do not mature to late endosomes or fuse with lysosomes. EEA1 continuously mediates homotypic fusion as long as the macropinosomes persist. |
| 15451443 |
These results suggest that EEA1 is involved in neuronal synaptic vesicle function and axonal transport and growth. EEA1 may undergo calcium-dependent conformational changes that are required for binding to SNAP-25. |
| 17113235 |
Impairment of internalization of specific glutamate receptors and their subsequent accumulation in the synapse may account for the neurological deficits observed in some patients developing EEA1 autoantibodies. |
| 17146146 |
results suggest that the local production of PtdIns(3)P implicates the fusion of macropinosomes via EEA1 as well as conventional early endosomes |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | RAB5A, member RAS oncogene family | early endosome antigen 1, 162kD | - | - | Pubmed |
| HPRD | RAB5A, member RAS oncogene family | early endosome antigen 1, 162kD | - | - | Pubmed |
| BIND | RAB5A, member RAS oncogene family | early endosome antigen 1, 162kD | Rab5 interacts with EEA.1. | - | Pubmed |
| HPRD | RAB5B, member RAS oncogene family | early endosome antigen 1, 162kD | - | - | Pubmed |
| HPRD | RAB5B, member RAS oncogene family | early endosome antigen 1, 162kD | - | - | Pubmed |
| HPRD | Ras associated protein Rab5C | early endosome antigen 1, 162kD | - | - | Pubmed |
| HPRD | RAB5C, member RAS oncogene family | EEA1 | - | - | Pubmed |
| HPRD | EEA1 | RAS-related protein RAB-22A | - | - | Pubmed |
| HPRD | early endosome antigen 1, 162kD | RAB22A | - | - | Pubmed |
| HPRD | early endosome antigen 1, 162kD | early endosome antigen 1, 162kD | - | - | Pubmed |
Recent Publications on EEA1: |  |
The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of synaptotagmin V.
We recently showed that the exocytosis regulator Synaptotagmin (Syt) V is... | 17th October, 2009
| INRS-Institut Armand-Frappier and Centre for Host-Parasite Interactions,
| PLoS Pathog. 2009 Oct;5(10):e1000628. Epub 2009 Oct 16.
DOI Direct Link |
[Effectors of GTPase Rab5 in endocytosis and signal transduction]
Small GTPase Rab5 is a multifunctional protein, which regulates early... | 15th October, 2009
| Miedzynarodowy Instytut Biologii Molekularnej i Komorkowej, Pracownia
| Postepy Biochem. 2009;55(2):171-80.
|
Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen-regulated protein 150-peptide complexes.
Heat shock proteins (HSPs) such as Hsp70, gp96, and Hsp90 have been shown... | 9th October, 2009
| Department of Pathology, Sapporo Medical University School of Medicine,
| J Immunol. 2009 Nov 1;183(9):5861-9. Epub 2009 Oct 7.
DOI Direct Link |
PKC{alpha}{beta}{gamma}- and PKC{delta}-dependent endocytosis of NBCe1-A and NBCe1-B in salivary parotid acinar cells.
We examined membrane trafficking of NBCe1-A and NBCe1-B variants of the... | 29th September, 2009
| 1University of Colorado and Denver Health Sciences Center.
| Am J Physiol Cell Physiol. 2009 Sep 30.
DOI Direct Link |
Sorting nexin 8 regulates endosome-to-Golgi transport.
Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family, whose... | 29th September, 2009
| Faculty Division The Norwegian Radium Hospital, Centre for Cancer
| Biochem Biophys Res Commun. 2009 Dec 4;390(1):109-14. Epub 2009 Sep 24.
DOI Direct Link |
→View more research publications. |
EEA1 results (if any) from reagent suppliers | 
|
Search Bioportfolio and other Life Science Sites for EEA1,
or search for EEA1 on BioPortfolio's antibody search engine.
This page has been viewed 286 times
Recent Search Terms used to find this page: EEA1 shRNA sequence | eea1 form 2009 | eea1 sirna sequence western blot | Early Endosome Antigen 1 | eea1 2009 | form eea1 2009 | eea1 form 2009 | eea1 form 2009 | eea1 2009 | .
Resources from the NCBI used on this page, NCBI's standard disclaimer applies.
|
