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OGT
| Symbol: | OGT | | Name(s): | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | FLJ23071, HRNT1, MGC22921, O-GLCNAC | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12136128 |
O-linked GlcNAc transferase participates in a hexosamine-dependent signaling pathway that is linked to insulin resistance and leptin production |
| 15896326 |
Thus, stably transfected HeLa cells provide an abundant source of enzyme that can be used to study the structure, function, and regulation of OGT. |
| 16105839 |
analysis of the catalytic domain of O-linked N-acetylglucosaminyl transferase |
| 14601650 |
a novel HLA-A0201-restricted cytotoxic T lymphocyte (CTL)-epitope (28-SLYKFSPFPL; FSP06) derived from a mutant OGT-protein |
| 11846551 |
homology between O-linked GlcNAc transferases and proteins of the glycogen phosphorylase superfamily |
| 15336570 |
OGT can respond rapidly to heat stress through the enhancement of nucleocytoplasmic protein O-GlcNAcylation. |
| 16966374 |
Overall, transcriptional inhibition is related to the integrated effect of O-GlcNAc by direct modification of critical elements of the transcriptome and indirectly through O-GlcNAc modification of the proteasome. |
| 15795231 |
By using a series of 4-methylumbelliferyl 2-deoxy-2-N-fluoroacetyl-beta-D-glucopyranoside substrates, Taft-like linear free energy analyses of these enzymes indicates that O-GlcNAcase uses a catalytic mechanism involving anchimeric assistance |
| 11773972 |
We have delineated the complete genomic structure of human OGT spanning approx 43 kb of genomic DNA in Xq13.1 |
| 15561949 |
Staining of OGT in streptozotocin diabetic rat liver is clearly diminished, but it was substantially restored after 6 days of insulin treatment | →View more information from publications. |
Recent Publications on OGT: |  |
O-GlcNAc protein modification in cancer cells increases in response to glucose deprivation through glycogen degradation.
When cellular glucose concentrations fall below normal levels, in general... | 17th October, 2009
| Department of Biology, Yonsei university, Korea, Republic of;
| J Biol Chem. 2009 Oct 15.
DOI Direct Link |
Detailing regulatory networks through large scale data integration.
MOTIVATION: Much of a cell's regulatory response to changing environments... | 15th October, 2009
| Department of Computer Science, Princeton University, 35 Olden Street,
| Bioinformatics. 2009 Oct 13.
DOI Direct Link |
O-GlcNAc cycling: implications for neurodegenerative disorders.
The dynamic post-translational modification of proteins by O-linked... | 29th September, 2009
| Laboratory of Cell Biology and Biochemistry, NIDDK, National Institutes of
| Int J Biochem Cell Biol. 2009 Nov;41(11):2134-46. Epub 2009 Mar 27.
DOI Direct Link |
A new supraglottic airway device: LMA-supreme, comparison with LMA-Proseal.
BACKGROUND AND OBJECTIVE: The LMA-Supreme() (S-LMA()) is a new... | 29th September, 2009
| Medical Faculty, Kocaeli University, Kocaeli, Turkey.
| Acta Anaesthesiol Scand. 2009 Aug;53(7):852-7. Epub 2009 May 6.
DOI Direct Link |
Glutamine Enhances Heat Shock Protein 70 Expression via Increased Hexosamine Biosynthetic Pathway Activity.
Background and Aims: Glutamine (GLN) plays a key role in cellular... | 25th September, 2009
| 1University of Colorado, Denver.
| Am J Physiol Cell Physiol. 2009 Sep 23.
DOI Direct Link |
→View more research publications. |
OGT results (if any) from reagent suppliers | 
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OGT Antibody (C-term)
Western blot analysis of OGT antibody (C-term) (Cat. #AP6695b) in mouse bladder tissue lysates (35ug/lane). OGT (arrow) was detected using the purified Pab. ...
http://www.abgent.com/products/catalog_no/AP6695b_OGT_Antibo...
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O6139 Anti-O-GlcNAc Transferase (SQ-17) antibody produced in ...
Synonym: Anti-O-linked N-Acetylglucosamine Transferase, Anti-OGT ... OGT(8473). rat ... Ogt(26295). mouse ... Ogt(108155). shipped in, dry ice ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?D7=0&N5...
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OGT 2115 sc-204144
OGT 2115 sc-204144 OGT 2115 sc-204144. ... OGT 2115. Click on image to enlarge. sc-204144. Download. Datasheets · Get Adobe Acrobat Reader ...
http://www.scbt.com/datasheet-204144.html...
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Antibodies to Modifying Enzymes/Other
mouse ... Ogt(108155) rat ... Ogt(26295), rat, mouse, human, ARR, IP, WB, pricing ... human ... OGT(8473), wide range, ELISA (i), ICC, IHC, IP, WB,
pricing ...
http://www.sigmaaldrich.com/etc/controller/controller-page.h...
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O-GlcNAc transferase (V-18) Antibody sc-22628
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, OGT, 8473, Xq13.1, NM_181672, ...
http://www.scbt.com/datasheet-22628-o-glcnac-transferase-v-1...
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Anti-O-GlcNAc Transferase (DM-17) antibody produced in rabbit ...
residues by O-GlcNAc transferase (OGT) is involved in the control of transcription, either by controlling ... OGT was also shown to interact with an
histone ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...
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OGT 2115 sc-204144
OGT 2115 sc-204144 OGT 2115 sc-204144. ... OGT 2115, sc-204144, 1 mg, $70. OGT 2115, sc-204144A, 10 mg, $181. 통화. US Dollars, Euro, Swiss Francs ...
http://www.scbt.com/ko/datasheet-204144.html...
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