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MADD
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18223207 |
we have identified an essential role for splice variants of the IG20 gene in TRAIL (tumor necrosis factor-related apoptosis-inducing ligand)resistance. |
| 16682944 |
Knockdown of MADD can render cells susceptible to spontaneous apoptosis but had no discernible effect on cell proliferation, colony size or cell cycle progression. MADD alone is sufficient and necessary for cancer cell survival. |
| 12410563 |
Denn is intimately involved in anti-apoptotic and cell survival processes in cancer cells |
| 17410194 |
data strongly indicate that germline mutations in SPI1 and MADD genes do not confer a high risk of chronic lymphocytic leukaemia and do not make a major contribution to the familial risk of the disease |
| 14695193 |
IG20 overexpression enhanced the combined apoptotic effects of TRAIL and gamma-irradiation on HeLa cells. |
| 14735464 |
DENN has anti-apoptotic and cell survival roles in tumor cells |
| 14716293 |
IG20 suppresses tumor cell survival and enhances susceptibility to apoptosis and cancer therapy. |
| 15208670 |
IG20 (MADD splice variant-5) enhances TRAIL-induced apoptosis by increasing recruitment of FADD and caspase-8 to the death-inducing signaling complex. |
| 17314102 |
MADD has a role in the control of cancer cell survival/death as a negative regulator of caspase-8 and confers significant resistance to TRAIL-induced apoptosis |
Recent Publications on MADD: |  |
Central nervous system and muscle involvement in an adolescent patient with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
We report an adolescent case of late-onset riboflavin-responsive multiple... | 29th September, 2009
| Department of Child Neurology, National Center of Neurology and Psychiatry
| Brain Dev. 2009 Sep 25.
DOI Direct Link |
Riboflavin responsive lipid storage myopathy caused by ETFDH gene mutations.
BACKGROUND: Lipid storage myopathy (LSM), defined by triglyceride... | 18th September, 2009
| Laboratory of Neuromuscular Disorders and Department of Neurology of Qilu
| J Neurol Neurosurg Psychiatry. 2009 Sep 15.
DOI Direct Link |
Novel mutations in ETFDH gene in Chinese patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
BACKGROUND: Multiple acyl-CoA dehydrogenase deficiency (MADD, OMIM 231680)... | 29th July, 2009
| Department of Chemical Pathology, The Chinese University of Hong Kong,
| Clin Chim Acta. 2009 Jun 27;404(2):95-9. Epub 2009 Mar 3.
DOI Direct Link |
ETFDH mutations, CoQ10 levels, and respiratory chain activities in patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency.
Multiple acyl-CoA dehydrogenase deficiency (MADD) is a metabolic disorder... | 29th July, 2009
| Department of Neuromuscular Research, National Institute of Neuroscience,
| Neuromuscul Disord. 2009 Mar;19(3):212-6. Epub 2009 Feb 26.
DOI Direct Link |
[Multiple acyl-CoA dehydrogenase deficiency (MADD): A curable cause of genetic muscular lipidosis.]
INTRODUCTION: Multiple acyl-CoA dehydrogenase deficiency (MADD) is a rare... | 14th July, 2009
| Centre de reference de pathologie neuromusculaire Paris-Est, groupe
| Rev Neurol (Paris). 2009 Jul 8.
DOI Direct Link |
→View more research publications. |
Press Releases on MADD:
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| Medical, Insurance, Automotive and Safety Groups Call on Congress to Make This the "Last Deadly Summer for Teens" by Swiftly Passing Federal Teen Driving Safety Bill |
3rd June, 2009 |
Saferoads4teens.org Coalition |
Motor vehicle crashes are #1 killer of nation's teens; During summer months a disproportionate number of teens die in crashes.
WASHINGTON, June 3 /PRNewswire-USNewswire
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| National Partnership to Meet, Evaluate Addiction Treatment as Component of New Justice Programs |
2nd June, 2009 |
National Partnership on Alcohol Misuse and Crime |
Coalition Working to Improve Public Safety, Reduce Costs for Overburdened Justice Agencies
WASHINGTON, June 2 /PRNewswire-USNewswire/ -- Representatives from more
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| MADD Delivers Nearly 7,000 Petitions to Governor Paterson Urging Ignition Interlocks For All Convicted DWI Offenders |
11th May, 2009 |
Mothers Against Drunk Driving |
ALBANY, N.Y., May 11 /PRNewswire-USNewswire/ -- Mothers Against Drunk Driving (MADD) New York delivered nearly 7,000 petitions to Governor Paterson's office today showing support for MADD&apos
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| Former MADD National President Joins Innocorp, ltd. |
8th April, 2009 |
Innocorp, ltd. |
VERONA, Wis., April 8 /PRNewswire/ -- While Wisconsin legislators brainstorm ways to reduce significant levels of drunk driving in the state, a private business continues to find innovative
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| Innocorp, ltd. Hires Former MADD National President |
8th April, 2009 |
Innocorp, ltd. |
VERONA, Wis., April 8 /PRNewswire/ -- While celebrity DUIs dominate the headlines, a private business continues to find innovative solutions to educate the world about the dangers
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MADD results (if any) from reagent suppliers | 
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MADD Antibody / MADD Antibodies
MADD Antibody / MADD Antibodies. ... MADD specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-madd.html...
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MADD Antibody
Rabbit polyclonal MADD antibody was raised against a peptide corresponding to amino acids near ... MADD antibody is human and mouse reactive. This product ...
http://www.prosci-inc.com/shop/pdf/1150.pdf...
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MADD antibodies: Signal Transduction > Metabolism > Mitochondrial ...
MADD antibodies. ... Image Abreview Publication. ab2043 · MADD antibody. WB, ICC /IF. Images. Rabbit polyclonal. Reacts with: Hu, Ms. ab76426 · MADD antibody ...
http://www.abcam.com/index.html?t=1480&pt=1&c=2252&ei=&mu=ra...
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MADD Antibody / MADD Antibodies
MADD Antibody / MADD Antibodies. ... MADD 特异siRNA, shRNA 质粒和shRNA 慢病毒 颗粒基因沉默子均有产品提供。 产品包括： ...
http://www.scbt.com/zh/table-madd.html...
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MADD proteins and peptides: Signal Transduction > Metabolism ...
MADD proteins and peptides. ... MADD proteins and peptides. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication ...
http://www.abcam.com/index.html?t=1480&pt=2&c=2252&ei=&mu=ra...
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MADD Antibody / MADD Antibodies
MADD El siRNA, el plásmido del sHRNA y los silenciadores especificos del gene de las partículas de Lentiviral del shRNA están también disponibles. ...
http://www.scbt.com/es/table-madd.html...
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Anti-MADD (CT)
Antibodies , Primary Antibodies , Signal Transduction , Anti-MADD (CT); Host: rabbit polyclonal; Species Reactivity: human, mouse, rat; Application: WB, ...
http://www.anaspec.com/products/product.asp?id=37289...
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