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CASK


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Symbol:CASK
Name(s):calcium/calmodulin-dependent serine protein kinase (MAGUK family)
Type:protein-coding
Organism:Homo sapiens
Synonyms:CMG, LIN2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11880184 Upregulation of CASK protein is associated with tumorigenesis of esophagus
15694377 Thus, we speculate that the regulation of cell growth mediated by CASK may be involved in Id1.
12110687 coordinated folding and association of the LIN-2, -7 domain
12511555 plasma membrane Ca2+ pump 4b/CI binds to Ca2+/calmodulin-dependent membrane-associated kinase CASK

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDMINT1calcium/calmodulin-dependent serine protein kinase--Pubmed
HPRDamyloid beta A4 precursor protein-binding, family A, member 1CASK--Pubmed
BINDamyloid beta A4 precursor protein-binding, family A, member 1calcium/calmodulin-dependent serine protein kinaseX11-ALPHA interacts with Lin-2.-Pubmed
HPRDATP2B4calcium/calmodulin-dependent serine protein kinase--Pubmed
HPRDATPase, Ca++ transporting, plasma membrane 4CASK--Pubmed
BINDcalcium channel, voltage-dependent, N type, alpha 1B subunitcalcium/calmodulin-dependent serine protein kinaseThe SH3 domain of CASK interacts with the carboxy-terminal proline-rich region (PRR) of Ca-alpha-1B.-Pubmed
HPRDSynapse associated protein 97calcium/calmodulin-dependent serine protein kinase--Pubmed
HPRDdiscs, large homolog 1CASK--Pubmed
BINDdiscs, large homolog 1calcium/calmodulin-dependent serine protein kinaseCASK interacts with DLG1 (SAP97).-Pubmed
HPRDpostsynaptic density protein 95calcium/calmodulin-dependent serine protein kinase--Pubmed

Recent Publications on CASK:

Pubmed Logo
Chapter 4 technological and microbiological aspects of traditional balsamic vinegar and their influence on quality and sensorial properties.
The term "balsamic" is widespread and popular all over the world of...
3rd November, 2009
Adv Food Nutr Res. 2009;58:137-82.
DOI Direct Link
Calcium/calmodulin-dependent serine protein kinase and mental retardation.
Calcium/calmodulin-dependent serine protein kinase (CASK) belongs to the...
23rd October, 2009
Institute of Molecular Biology, Academia Sinica, Taipei, Taiwan. Ann Neurol. 2009 Oct;66(4):438-43.
DOI Direct Link
Necl2 regulates epidermal adhesion and wound repair.
Differential expression of cell adhesion molecules regulates stem cell...
14th October, 2009
Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Development. 2009 Oct;136(20):3505-14.
DOI Direct Link
High levels of structural disorder in scaffold proteins as exemplified by a novel neuronal protein, CASK-interactive protein1.
CASK-interactive protein1 is a newly recognized post-synaptic density...
14th October, 2009
Department of Medical Chemistry, Semmelweis University Medical School, FEBS J. 2009 Jul;276(14):3744-56. Epub 2009 Jun 11.
DOI Direct Link
Post-translational modification of CASK leads to its proteasome-dependent degradation.
CASK is a member of the membrane-associated guanylate kinase family. In...
29th September, 2009
Department of Biology, University of Western Ontario, London, ON, Canada Int J Biochem Cell Biol. 2009 Sep 23.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Probiotics as a Prophylactic Aid in Women With Recurrent Urinary Tract Infections (UTI's)

Patents:

Patents logo
US Patent No.Title
7289836 Optical-based sensing devices
7372933 Radioactive-material container, metal gasket for sealing the radioactive-material container, and method of manufacturing the metal gasket
7384740 Polynucleotide and protein involved in synaptogenesis variants thereof and their therapeutic and diagnostic uses
7399467 Antibodies for oncogenic strains of HPV and methods of their use
7410950 Peptides of CaV2.2 that inhibit pain

View more patents.

CASK results (if any) from reagent suppliers

Google CSE Logo
CASK antibody (ab11343) | Abcam
Rabbit polyclonal to CASK. Calmodulin sensitive kinase (CASK/mLIN-2) is a ~112- kDa member of the membrane associated quanylate kinase (MAGUK) protein family
...
http://www.abcam.com/cask-antibody-ab11343.html...

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CASK Antibody / CASK Antibodies
CASK Antibody / CASK Antibodies. ... CASK specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-cask.html...

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CASK Antibody
CASK binds to Neurexin to stabilize pre- and post-synaptic structures (1). While most of CASK ... the importance of CASK, transgenic mice with insertional ...
http://www.cellsignal.com/pdf/2878.pdf...

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Cask Antibody (C-term)
Western blot analysis of CASK (arrow) using Cask Antibody (C-term) (Cat.#AP7212a ). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or ...
http://www.abgent.com/products/catalog_no/AP7212a_Cask_Antib...

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CASK Antibody #2878
Polyclonal antibodies are produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to the amino-terminus of CASK. ...
http://www.cellsignal.com/products/2878.html...

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CASK (C-6) Antibody sc-13158
Western blot analysis of CASK expression in MIA PaCa-2 (A) whole cell lysate ... Blot probed with CASK (C-6): sc-13158. α-actinin (H-2): sc-17829 used as ...
http://www.scbt.com/datasheet-13158-cask-c-6-antibody.html...

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Anti-CASK/LIN2 (KA-17) antibody produced in rabbit (C4856) - Datasheet
CASK/Lin-2 seems to be ubiquitously expressed, but is predominant in the brain.3 ,4 It localizes ... cells.2,3 CASK/Lin-2 is translocated into the nucleus to ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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