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ABCB11


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Symbol:ABCB11
Name(s):ATP-binding cassette, sub-family B (MDR/TAP), member 11
Type:protein-coding
Organism:Homo sapiens
Synonyms:ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12825874 Observational study of gene-disease association. (HuGE Navigator)
14999697 Observational study of gene-disease association. (HuGE Navigator)
15077010 Observational study of gene-disease association. (HuGE Navigator)
16763017 Observational study of genotype prevalence. (HuGE Navigator)
16941683 Observational study of gene-disease association. (HuGE Navigator)
17264802 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
17622941 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18176959 Observational study of gene-disease association. (HuGE Navigator)
16941683 The gallstone trait is not allelic to progressive familial cholestasis at the ABCB11 locus.
14999697 Data do not support a strong role of BSEP and MDR3 genetic variations in the pathogenesis of primary biliary cirrhosis and primary sclerosing cholangitis.

View more information from publications.

Recent Publications on ABCB11:

Pubmed Logo
ABCB11 gene mutations in Chinese children with progressive intrahepatic cholestasis and low gamma glutamyltransferase.
Abstract Background: Progressive familial intrahepatic cholestasis type 2...
23rd October, 2009
The Center for Pediatric Liver Diseases, Children's Hospital of Fudan Liver Int. 2009 Oct 21.
DOI Direct Link
Recent insights into the function and regulation of the bile salt export pump (ABCB11).
PURPOSE OF REVIEW: Generation of bile is an important function of the...
23rd October, 2009
Division of Clinical Pharmacology and Toxicology, Department of Medicine, Curr Opin Lipidol. 2009 Jun;20(3):176-81.
DOI Direct Link
Combined features of low phospholipid-associated cholelithiasis and progressive familial intrahepatic cholestasis 3.
Abstract Adenosine triphosphate-binding cassette, subfamily B, member 4...
21st October, 2009
UPMC Universite Paris, Paris, France. Liver Int. 2009 Oct 19.
DOI Direct Link
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.
Recent advances in next generation sequencing have made it possible to...
21st October, 2009
Molecular Oncology, BC Cancer Agency, 675 West 10th Avenue, Vancouver V5Z Nature. 2009 Oct 8;461(7265):809-13.
DOI Direct Link
Genetic variations of the ABC transporter gene ABCB11 encoding the human bile salt export pump (BSEP) in a Japanese population.
The bile salt export pump (BSEP) encoded by ABCB11 is located in the...
9th October, 2009
Project Team for Pharmacogenetics, National Institute of Health Sciences, Drug Metab Pharmacokinet. 2009;24(3):277-81.

View more research publications.

BioNews Results for ABCB11

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BioPortfolio Logo
Research from Graduate School reveals new findings on drug development
Pharmacy Choice:  Oct 21 2009 12:14PM Matching: abcb11

Patents:

Patents logo
US Patent No.Title
7595311 Azepinoindole derivatives as pharmaceutical agents
7485634 Azepinoindole and pyridoindole derivatives as pharmaceutical agents
7485468 Molecular targets and compounds, and methods to identify the same, useful in the treatment of joint degenerative and inflammatory diseases
7291461 Methods for identifying small molecules that modulate premature translation termination and nonsense mRNA decay
7229825 Double-transfected cell line useful for the identification of transport inhibitors

View more patents.

ABCB11 results (if any) from reagent suppliers

Google CSE Logo
ABCB11 antibody - Carboxyterminal end (ab71793) | Abcam
Rabbit polyclonal to ABCB11 - Carboxyterminal end. Bile formation is an important function of the liver. It is mediated by hepatocytes which generate
bile ...
http://www.abcam.com/ABCB11-antibody-Carboxyterminal-end-ab7...

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BSEP (N-16) Antibody sc-17292
Cloning of the dog bile salt export pump (BSEP; ABCB11) and functional comparison with the human and rat proteins. BioParmaceutics & Drug Disposition.
...
http://www.scbt.com/datasheet-17292-bsep-n-16-antibody.html...

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ABCB11 antibodies: Signal Transduction > Metabolism > Lipid ...
ABCB11 antibodies. ... Image Abreview Publication. ab71793 · ABCB11 antibody - Carboxyterminal end. IHC-P, WB, ELISA. Images. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=163837&pt=1&c=3612&ei=&mu=...

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BSEP (F-6) Antibody sc-74500
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, ABCB11, 8647, 2q24.3, NM_003742 ...
http://www.scbt.com/datasheet-74500-bsep-f-6-antibody.html...

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The Abcam catalog
Applications (see key) & Reactivity (see key). Image Abreview Publication. ab71793 · ABCB11 antibody - Carboxyterminal end. IHC-P, WB, ELISA ...
http://www.abcam.com/index.html?t=163837&pt=1...

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Abgent - Cell and Function Antibodies
AP6307a, ABAD Antibody (Center), WB, E, H. AP6109a, ABCB10 Antibody (N-term), E, H. AP6110a, ABCB11 Antibody (C-term), WB, IHC, E, H, M ...
http://www.abgent.com/products/category/cell_function...

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Cell Surface Molecules / GPCRs
ATP-binding cassette sub-family B (MDR/TAP) member 11 (ABCB11) polyclonal antibody, PAB-10458, $175.00. ATP-binding cassette sub-family B (MDR/TAP) member
4 ...
http://www.orbigen.com/dictionary/cat1089.htm...

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