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EDG6


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Gene DB Home
Symbol:EDG6
Name(s):endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 6
Type:protein-coding
Organism:Homo sapiens
Synonyms:LPC1, S1P4, S1PR4, SLP4
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15298705 Mutation of the ligand selectivity residue from glutamic acid to glutamine confers lysophosphatidic acid sensitivity with preference for short-chain species

Recent Publications on EDG6:

Pubmed Logo
Non-Edg family lysophosphatidic acid (LPA) receptors.
Lysophosphatidic acid (LPA; 1- or 2-acyl-sn-glycero-3-phosphate) is a...
16th June, 2009
Department of Biochemistry and Molecular Biology, Faculty of Medicine, The Prostaglandins Other Lipid Mediat. 2009 Sep;89(3-4):57-65. Epub 2009 Jun
DOI Direct Link
FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase.
In T cells, the PI3K pathway promotes proliferation and survival induced...
16th September, 2008
Institut Cochin, Universite Paris Descartes, Centre National de la J Immunol. 2008 Sep 1;181(5):2980-9.
Sphingosine-1-phosphate receptor expression and signaling correlate with uterine prostaglandin-endoperoxide synthase 2 expression and angiogenesis during early pregnancy.
Signaling mechanisms coordinating uterine angiogenesis and tissue...
2nd December, 2005
Vincent Center for Reproductive Biology, Vincent Obstetrics and Gynecology Biol Reprod. 2006 Mar;74(3):569-76. Epub 2005 Nov 30.
DOI Direct Link
The blockade of cyclopiazonic acid-induced store-operated Ca2+ entry pathway by YC-1 in neutrophils.
In the presence of external Ca2+, pretreatment of neutrophils with...
26th January, 2005
Department of Education and Research, Taichung Veterans General Hospital, Biochem Pharmacol. 2004 Nov 15;68(10):2053-64.
DOI Direct Link
Sphingosine signaling and atherogenesis.
Sphingosine-1-phosphate (S1P) has diverse biological functions acting...
1st September, 2004
Division of Experimental Vascular Research, Institute of Medicine, Lund Acta Pharmacol Sin. 2004 Jul;25(7):849-54.

View more research publications.

Patents:

Patents logo
US Patent No.Title
7611851 Canis sphingosine 1-phosphate receptor isoform 1
7169390 Compositions and methods for the treatment and prevention of cancer, angiogenesis, and inflammation
7141383 EDG8 receptor, its preparation and use
7063966 Chimeric G protein coupled receptors
6881546 Compositions and methods for the treatment and prevention of cardiovascular diseases and disorders, and for identifying agents therapeutic therefor

View more patents.

EDG6 results (if any) from reagent suppliers

Google CSE Logo
EDG-6 Antibody / EDG-6 Antibodies
EDG-6 Antibody / EDG-6 Antibodies. ... EDG-6 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-edg-6.html...

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EDG6 Antibody (N-term)
EDG6 Antibody (N-term) Cell Function, EDG6 Antibody (N-term) Cell Signaling.
http://www.abgent.com/products/catalog_no/AP6142a...

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EDG-6 Antibody / EDG-6 Antibodies
EDG-6 Antibody / EDG-6 Antibodies. ... EDG-6 spezifische siRNA, sHRNA Plasmide und shRNA Lentivirale Partikel Gen Silencer sind ebenfalls erhältlich. ...
http://www.scbt.com/de/table-edg-6.html...

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EDG6 (S1P4) (C Terminal), FITC Conjugate. Mouse
EDG6 (S1P4) belongs to a family of G-protein coupled receptors ...EDG-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) ...
http://www.exalpha.com/pdfs/X1626M.pdf...

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EDG-6 Antibody / EDG-6 Antibodies
EDG-6 Antibody / EDG-6 Antibodies. ... EDG-6 specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-edg-6.html...

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Exalpha Biologicals, Inc.
X1593P, Sphingosine 1 Phosphate 4 Receptor (NT) (EDG6) NT, Polyclonal Antibody, 100 µg, $425, Datasheet (pdf) · Z135M, VipR 1 (Vasoactive Intestinal Peptide ...
http://www.exalpha.com/Searchresults1.php?menuvalue=Category...

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Monoclonal Anti-S1P4, C-Terminal from mouse (E9529) - Datasheet
(EDG-6), C-Terminal (mouse IgG1 isotype) is derived from the hybridoma produced by the fusion of ... EDG-6 is specifically expressed in fetal and adult ...
http://www.sigmaaldrich.com/etc/medialib/docs/Sigma/Datashee...

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