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CBR3


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Symbol:CBR3
Name(s):carbonyl reductase 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:hCBR3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15537833 The common carbonyl reductase 3 (CBR3)valine244methionine polymorphism encodes for CBR3 isoforms with distinctive enzymatic properties, as revealed in DNA variation panels from 10 ethnic groups.
10728668 carbonyl reductase has an important function in modifying the metastatic behavior of malignant tumors.
11592776 Decreased Carbonyl Reductase expression in epithelial ovarian cancer is associated with RLN metastasis and poor survival

Recent Publications on CBR3:

Pubmed Logo
Identification of the promoter of human carbonyl reductase 3 (CBR3) and impact of common promoter polymorphisms on hepatic CBR3 mRNA expression.
PURPOSE: Recent studies suggest that polymorphisms in human carbonyl...
3rd November, 2009
Department of Pharmaceutical Sciences, The State University of New York at Pharm Res. 2009 Sep;26(9):2209-15. Epub 2009 Jul 10.
DOI Direct Link
Structural basis for substrate specificity in human monomeric carbonyl reductases.
Carbonyl reduction constitutes a phase I reaction for many xenobiotics and...
21st October, 2009
Structural Genomics Consortium, University of Oxford, Headington, United PLoS One. 2009 Oct 20;4(10):e7113.
DOI Direct Link
Importance of the substrate-binding loop region of human monomeric carbonyl reductases in catalysis and coenzyme binding.
AIMS: Monomeric carbonyl reductase 1 (CBR1) and 3 (CBR3) are members of...
14th August, 2009
Laboratory of Biochemistry, Faculty of Pharmacy, Osaka Ohtani University, Life Sci. 2009 Aug 12;85(7-8):303-8. Epub 2009 Jun 23.
DOI Direct Link
Nitric oxide synthase variants and disease-free survival among treated and untreated breast cancer patients in a Southwest Oncology Group clinical trial.
PURPOSE: Numerous chemotherapeutic agents are cytotoxic through generation...
13th August, 2009
Department of Cancer Prevention and Control, Roswell Park Cancer Clin Cancer Res. 2009 Aug 15;15(16):5258-66. Epub 2009 Aug 11.
DOI Direct Link
Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.
Human carbonyl reductase is a member of the short-chain...
28th February, 2009
Institute of Toxicology and Pharmacology for Natural Scientists, Chem Biol Interact. 2009 Mar 16;178(1-3):234-41. Epub 2008 Nov 18.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7549036 Management of access to data from memory
5422851 Semiconductor memory device capable of verifying use of redundant circuit
6044251 TV/FM receiver for multimedia applications
6125269 TV FM receiver for multimedia applications
6181819 Image processing apparatus including means for judging a chromatic portion of an image

View more patents.

CBR3 results (if any) from reagent suppliers

Google CSE Logo
Anti-CBR3 Polyclonal Antibody
Polyclonal Antibody against CBR3 for use in Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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CBR3 antibodies: Signal Transduction > Metabolism > Alcohol ...
CBR3 antibodies. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab39279 · CBR3 antibody. Fast Track. Goat polyclonal ...
http://www.abcam.com/index.html?t=115543&pt=1&c=3622&ei=&mu=...

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Carbonyl reductase 3 (E-18) Antibody sc-70220
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CBR3, 874, 21q22.12, NM_001236 ...
http://www.scbt.com/ko/datasheet-70220-carbonyl-reductase-3-...

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Abcam antibodies and reagents product map
... ALDH3B1 antibodies (2) · ALDH7A1 antibodies (3) · Alcohol Dehydrogenase antibodies (7) · Aldehyde dehydrogenase 10 antibodies (1) · CBR3 antibodies (1)
...
http://www.abcam.com/index.html?c=2105...

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Carbonyl reductase 3 (E-18) Antibody sc-70220
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, CBR3, 874, 21q22.12, NM_001236 ...
http://www.scbt.com/ja/datasheet-70220-carbonyl-reductase-3-...

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Carbonyl reductase 3 (C-16) Antibody sc-70218
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, CBR3, 874, 21q22.12, NM_001236 · O75828 ...
http://www.scbt.com/de/datasheet-70218-carbonyl-reductase-3-...

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Carbonyl reductase 3 (C-16) Antibody sc-70218
Species, Nome del gene, Codice del gene, Locus cromosoma, Isoform (mRNA) Accession #, codice accesso proteina, Numero d' ordine. Human, CBR3, 874, 21q22.
12 ...
http://www.scbt.com/it/datasheet-70218-carbonyl-reductase-3-...

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