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RAB11A


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Symbol:RAB11A
Name(s):RAB11A, member RAS oncogene family
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC1490, YL8
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17854769 These data therefore show that (i) Rab11a regulates cell surface abundance of both GLUT4 and FAT/CD36.
17538027 These results show that Rab11A and Langerin are required for BG biogenesis, and they illustrate the role played by a Rab GTPase in the formation of a specialized subcompartment within the endocytic-recycling system.
17462998 myosin Vb is required for CFTR recycling in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells
17476295 Rab11 plays a role in the intracellular trafficking of various types of LG-molecule from the TGN to the cell surface
17157409 Rab 11 and Arf6 function synergistically in the switch from furrowing to abscission, as well as in the terminal stage of abscission
16473307 We conclude that the glutamine residue of Rab11a at position 70 is not strictly essential for GTPase activity of this protein in contrast to Ras and other Rab proteins.
15190120 there is a pivotal role for rab11 in regulating the traffic of a G protein-coupled receptor at the level of the recycling endosome
15188492 Rab11a, RPL7, and RPL28 showed moderate levels of differential expression in esophageal squamous cell carcinoma
16126723 an interaction between Rab11 and TPbeta directs TPbeta recycling
14699104 mutation impairs a specific subset of Rab11 interactions, possibly those involved in cytoskeleton-based movements driving the slow recycling pathway

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDGDP dissociation inhibitor 2Ras-related protein Rab-11A--Pubmed
HPRDGDP dissociation inhibitor 2 isoform 1Ras family, member rab 11A--Pubmed
HPRDMyosin 5BRas-related protein Rab-11A--Pubmed
HPRDunnamed protein productRas family, member rab 11A--Pubmed
HPRDSyntaxin 4ARas-related protein Rab-11A--Pubmed
HPRDsyntaxin 4Ras family, member rab 11A--Pubmed
HPRDRas family, member rab 11AWD repeat domain 44 protein--Pubmed
HPRDRas-related protein Rab-11Arab11-family interacting protein 3--Pubmed
HPRDRas-related protein Rab-11ARAB11 family interacting protein 2--Pubmed
HPRDRas-related protein Rab-11ARAB11 family interacting protein 2--Pubmed

Recent Publications on RAB11A:

Pubmed Logo
Requirement of myosin Vb.Rab11a.Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface.
Niemann-Pick C1-like 1 (NPC1L1) plays a critical role in the enterohepatic...
15th September, 2009
State Key Laboratory of Molecular Biology, Institute of Biochemistry and J Biol Chem. 2009 Aug 14;284(33):22481-90. Epub 2009 Jun 19.
DOI Direct Link
Class I Rab11-Family Interacting Proteins are binding targets for the Rab14 GTPase.
Background Information Rab11 and Rab14 are two related Rab GTPases that...
26th August, 2009
Biol Cell. 2009 Aug 25.
DOI Direct Link
Characterization of the MAL2-positive compartment in oligodendrocytes.
Oligodendrocytes (OLs), the myelin-producing cells of the central nervous...
18th August, 2009
Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Cantoblanco, 28049 Exp Cell Res. 2009 Nov 15;315(19):3453-65. Epub 2009 Aug 13.
DOI Direct Link
Exploring the human genome with functional maps.
Human genomic data of many types are readily available, but the complexity...
4th August, 2009
Department of Computer Science, Princeton University, Princeton, New Genome Res. 2009 Jun;19(6):1093-106. Epub 2009 Feb 26.
DOI Direct Link
Regulation of cell death by recycling endosomes and golgi membrane dynamics via a pathway involving Src-family kinases, Cdc42 and Rab11a.
Actin dynamics and membrane trafficking influence cell commitment to...
31st July, 2009
Centre de Recherche en Cancerologie de l'Universite Laval, L'Hotel-Dieu de Mol Biol Cell. 2009 Sep;20(18):4091-106. Epub 2009 Jul 29.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6936417 Gene expression in bladder tumors
7189507 Methods of diagnosis of ovarian cancer, compositions and methods of screening for modulators of ovarian cancer
7251568 Methods and compositions for regulating bone and cartilage formation
7329422 Pharmaceutical compositions

View more patents.

RAB11A results (if any) from reagent suppliers

Google CSE Logo
Rab11A antibody (ab2921) | Abcam
Goat polyclonal to Rab11A. Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases.
http://www.abcam.com/Rab11A-antibody-ab2921.html...

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Rab11a Antibody #2413
Polyclonal antibodies are produced by immunizing animals with a synthetic peptide (KLH-coupled) corresponding to residues surrounding Arg184 of human
Rab11a ...
http://www.cellsignal.com/products/2413.html...

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Rab11A antibodies: Cancer > Signal transduction > G protein ...
Rab11A antibodies. ... Rab11A antibody [7C10]. WB, ELISA. Mouse monoclonal. Reacts with: Hu. Terms and conditions · Legal · Privacy policy ...
http://www.abcam.com/index.html?t=10899&pt=1&c=4299&ei=&mu=r...

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Rab11b Antibody #2414
Rab11a, Rab11b and Rab25 are members of the Rab11 family of small Ras-like GTPases. Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the
...
http://www.cellsignal.com/products/2414.html...

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Antibodies to Endosomes
Rab11a(81830) mouse ... Rab11a(53869), rat, human, mouse, WB, pricing. R4654, Anti-Rab5 antibody produced in rabbit, (polyclonal) ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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Rab Family Antibody Sampler Kit #9385
Rab11 (isoforms Rab11a and Rab11b) functions as a key regulator in the ... Despite some overlap, distinct differences exist between Rab11a and Rab11b in
...
http://www.cellsignal.com/products/9385.html...

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Antibody Products - Protein and Antibody Solutions Provider - GenWay
Mouse monoclonal [2F3] to Rab11A; 8766; RAB11A; 605570; P62491; MGC1490; YL8;; Ras-related protein ... 20-272-190348, Rab11A [7C10] Related Product Names: ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=R...

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