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SAP30


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Gene DB Home
Symbol:SAP30
Name(s):Sin3A-associated protein, 30kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:-
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17897615 PBF binds to SAP30 and represses transcription via recruitment of the HDAC1 co-repressor complex
17672918 occurrence of an unusual TG 3' splice site in intron 1
12788099 The interaction domains between YY1 and SAP30 were mapped to the C-terminal segment of YY1 (295-414) and the C-terminal 91 amino acid region of SAP30.
15005689 The SAP30 gene may be involved in basal cell carcinogenesis.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDhistone deacetylase 1Sin3A-associated protein, 30kDa--Pubmed
HPRDhistone deacetylase 1Sin3A-associated protein, 30kDa--Pubmed
HPRDInhibitor of growth 1Sin3A-associated protein, 30kDa--Pubmed
HPRDinhibitor of growth family, member 1 isoform DSAP30--Pubmed
HPRDRetinoblastoma binding protein 4Sin3A-associated protein, 30kDa--Pubmed
HPRDretinoblastoma binding protein 4SAP30--Pubmed
HPRDYY1 transcription factorSin3A-associated protein, 30kDa--Pubmed
HPRDYY1 transcription factorSin3A-associated protein, 30kDa--Pubmed
HPRDSAP30CBF1 interacting corepressor--Pubmed
HPRDSAP30nuclear receptor co-repressor 2--Pubmed

Recent Publications on SAP30:

Pubmed Logo
Sin3: master scaffold and transcriptional corepressor.
Sin3 was isolated over two decades ago as a negative regulator of...
31st October, 2009
Department of Biochemistry, Mayo Clinic, Rochester, MN 55905, USA. Biochim Biophys Acta. 2009 Jun-Aug;1789(6-8):443-50. Epub 2009 Jun 6.
DOI Direct Link
The SAGA and Rpd3 chromatin modification complexes dynamically regulate heat shock gene structure and expression.
The chromatin structure of heat shock protein (HSP)-encoding genes...
18th September, 2009
LSUHSC, United States. J Biol Chem. 2009 Sep 15.
DOI Direct Link
Phylogenetic analysis of the SAP30 family of transcriptional regulators reveals functional divergence in the domain that binds the nuclear matrix.
BACKGROUND: Deacetylation of histones plays a fundamental role in gene...
1st August, 2009
Paediatric Research Centre, University of Tampere Medical School and BMC Evol Biol. 2009 Jun 30;9:149.
DOI Direct Link
Solution structure of a novel zinc finger motif in the SAP30 polypeptide of the Sin3 corepressor complex and its potential role in nucleic acid recognition.
Giant chromatin-modifying complexes regulate gene transcription in...
6th June, 2009
Department of Biochemistry, Molecular Biology, and Cell Biology, Nucleic Acids Res. 2009 Apr;37(7):2142-52. Epub 2009 Feb 17.
DOI Direct Link
DNA-binding and -bending activities of SAP30L and SAP30 are mediated by a zinc-dependent module and monophosphoinositides.
Deacetylation of histones is carried out by a corepressor complex in which...
27th January, 2009
Paediatric Research Centre, University of Tampere Medical School and Mol Cell Biol. 2009 Jan;29(2):342-56. Epub 2008 Nov 17.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Relationship Between Erythropoietin Administration and Stress Responses in Trauma Patients

Patents:

Patents logo
US Patent No.Title
7608682 Substrates of N-end rule ubiquitylation and methods for measuring the ubiquitylation of these substrates
7094876 Human cDNAs and proteins and uses thereof
7074901 Isolated human vCOL16A1 polypeptide and fragments thereof
7074584 Yeast arrays, methods of making such arrays, and methods of analyzing such arrays
7074571 Serine carboxypeptidase hx (SCPhx) and compositions thereof

View more patents.

SAP30 results (if any) from reagent suppliers

Google CSE Logo
SAP 30 (CA14) Antibody sc-130425
SAP 30 shRNA (h) Lentiviral Particles, sc-44086-V, 200 µl ... SAP 30 (CA14): sc- 130425. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human ...
http://www.scbt.com/datasheet-130425-sap-30-ca14-antibody.ht...

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SAP30 antibodies: Chromatin and Nuclear Signaling > Chromatin ...
SAP30 antibodies. ... SAP30 antibody. IP, WB. Rabbit polyclonal. Reacts with: Sc . ab56527 · SAP30 antibody. WB. Images. Mouse monoclonal. Reacts with: ...
http://www.abcam.com/index.html?t=30141&pt=1&c=4174&ei=&mu=r...

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Sap 30 (yN-19) Antibody sc-8474
Sap 30 (yN-19) Antikörper sc-8474 Sap 30 (yN-19) Antibody sc-8474.
http://www.scbt.com/de/datasheet-8474-sap-30-yn-19-antibody....

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Protein Modification / Acetylation - Protein Modification Antibody
AP1922b, Reptin/TIP49B/RUVB2 Antibody (Center), WB, E, H. AT3771a, SAP30 monoclonal antibody (M02), ELISA,IHC-P,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...

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SAP Antibody / SAP Antibodies
Sap 30 (yN-19) Antibody, sc-8474, goat IgG, N-terminus (Sc), WB, ELISA, S. cerevisiae. Sap 30 (yC-21) Antibody, sc-8475, goat IgG, C-terminus (Sc) ...
http://www.scbt.com/table-sap.html...

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HDAC2 peptide, HDAC2 (Ab-394) Antibody Blocking Peptide peptide
Interacts with ATR, DNMT1, MINT, HDAC7, HDAC10, HCFC1, NRIP1, MJD2A/JHDM3A, SAP30, SETDB1 and SUV39H1. Interacts with the non-histone region of H2AFY. ...
http://www.genwaybio.com/product_info.php?products_id=213340...

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Sap 30 (yN-19) Antibody sc-8474
Sap 30 (yN-19) P, sc-8474 P (peptide), 100 µg/0.5 ml ... Sap 30 (yN-19): sc-8474 antibody 및 Sap 30 (yN-19) antibody conjugates를 사용한 논문들을 보세요. ...
http://www.scbt.com/ko/datasheet-8474-sap-30-yn-19-antibody....

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