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ACTN3


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Gene DB Home
Symbol:ACTN3
Name(s):actinin, alpha 3
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC117002, MGC117005
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
12879365 Observational study of gene-disease association. (HuGE Navigator)
15718405 Observational study of gene-disease association. (HuGE Navigator)
15817725 Observational study of gene-disease association. (HuGE Navigator)
16612741 Observational study of gene-disease association. (HuGE Navigator)
17033684 Observational study of gene-disease association. (HuGE Navigator)
17339648 Observational study of gene-disease association. (HuGE Navigator)
17468578 Observational study of gene-disease association. (HuGE Navigator)
17550918 Observational study of gene-disease association. (HuGE Navigator)
17560787 Observational study of gene-disease association. (HuGE Navigator)
17627799 Observational study of gene-disease association. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDactinin, alpha 3myopalladin--Pubmed

Recent Publications on ACTN3:

Pubmed Logo
ACTN3 R577X polymorphism and Israeli top-level athletes.
A common genetic variation in the alpha-actinin-3 ( ACTN3) gene causes a...
30th October, 2009
The Zinman College of Physical Education and Sports Sciences at the Int J Sports Med. 2009 Sep;30(9):695-8. Epub 2009 Jun 18.
DOI Direct Link
Sequence and expression of the zebrafish alpha-actinin gene family reveals conservation and diversification among vertebrates.
Alpha-actinins are actin microfilament crosslinking proteins. Vertebrate...
21st October, 2009
Department of Biochemistry and Cell Biology, Rice University, Houston, Dev Dyn. 2009 Nov;238(11):2936-47.
DOI Direct Link
Is there an association between ACTN3 R577X polymorphism and muscle power phenotypes in young, non-athletic adults?
We investigated the association between ACTN3 R577X polymorphism and...
8th October, 2009
Department of Physiology and Biomedicine, Universidad Europea de Madrid, Scand J Med Sci Sports. 2009 Oct 5.
DOI Direct Link
alpha-actinin-3 and performance.
The human sarcomeric alpha-actinins (ACTN2 and ACTN3) are major structural...
22nd August, 2009
Institute for Neuroscience and Muscle Research, Children's Hospital at Med Sport Sci. 2009;54:88-101. Epub 2009 Aug 17.
DOI Direct Link
Fast-twitch sarcomeric and glycolytic enzyme protein loss in inclusion body myositis.
Inclusion body myositis (IBM) is an inflammatory disease of skeletal...
6th August, 2009
Harvard-Partners Center for Genetics and Genomics, Proteomics Core, Muscle Nerve. 2009 Jun;39(6):739-53.
DOI Direct Link

View more research publications.

BioNews Results for ACTN3

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The ACTN3 R577X polymorphism in Russian endurance athletes
British Journal of Sports Medicine:  Oct 15 2009 12:51AM Matching: actn3
World-class performance in lightweight rowing: Is it genetically influenced? A comparison with cyclists, runners and non-athletes
British Journal of Sports Medicine:  Oct 15 2009 12:50AM Matching: actn3

Patents:

Patents logo
US Patent No.Title
7588771 Microorganisms for therapy
6335170 Gene expression in bladder tumors
6727063 Single nucleotide polymorphisms in genes
6770461 High bone mass gene of 11q13.3
6780609 High bone mass gene of 1.1q13.3

View more patents.

ACTN3 results (if any) from reagent suppliers

Google CSE Logo
ACTN3 antibody (ab65067) | Abcam
Rabbit polyclonal to ACTN3. ACTN3 (Alpha-actinin) is an actin-binding protein and is expressed only in a subset of type 2 skeletal muscle fibers.
http://www.abcam.com/ACTN3-antibody-ab65067.html...

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A7732 Monoclonal Anti-α-Actinin (Sarcomeric) antibody produced in ...
Synonym: Anti-Actinin α3, Anti-ACTN3, Anti-Alpha-actinin skeletal muscle isoform 3 ... mouse ... Actn3(11474). shipped in, dry ice. storage temp. −20°C ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A773...

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ACTN3 antibodies: Signal Transduction > Cytoskeleton / ECM ...
ACTN3 antibodies. ... Image Abreview Publication. ab65067 · ACTN3 antibody. WB, ELISA. Images. Rabbit polyclonal. Reacts with: Hu, Ms, Rat ...
http://www.abcam.com/index.html?t=249589&pt=1&c=815&ei=&mu=r...

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α-actinin (N-19) Antibody sc-7453
Mouse, Actn3, 11474, 19 A, O88990, N/A. Mouse, Actn4, 60595, 7 A3, P57780, N/A. Mouse, Actn1, 109711, 12 C3, Q7TPR4, N/A. Ordering Information ...
http://www.scbt.com/datasheet-7453-alpha-actinin-n-19-antibo...

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Sarcomeric Alpha Actinin antibody [EA-53] (ab9465) | Abcam
ACTN2 has the ability to form both homo- and heterodimers (with ACTN3). Alternative namesSarcomeric Alpha Actinin antibody [EA-53] (ab9465). Database
links ...
http://www.abcam.com/Sarcomeric-Alpha-Actinin-antibody-EA-53...

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A7811 Monoclonal Anti-α-Actinin (Sarcomeric) antibody produced in ...
Synonym: Anti-Actinin α3, Anti-ACTN3, Anti-Alpha-actinin skeletal muscle isoform 3. MDL number: MFCD00164521. Details. Related Products. References. Reviews ...
http://www.sigmaaldrich.com/catalog/ProductDetail.do?N4=A781...

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α-actinin (B-12) Antibody sc-166524
Human, ACTN3, 89, 11q13.1, NM_001102, NM_001103, NM_001104, NM_001130004, NM_001130005, NM_004924 · Q08043 · 102574. Mouse, Actn1, 109711, 12 C3, Q7TPR4
...
http://www.scbt.com/datasheet-166524-alpha-actinin-b-12-anti...

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