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«CCNA1

Below is an extended CCNA1 publications listing. Click here to return to the gene page.

Gene Information from Publications

Publication Link Summary of findings
17530187 Over expression of H179Y-mutant p53 promoted G1 to S phase transition with enlarged cell size and increased cyclin A1 and Cdk4 expression in HELF cells.
17455244 these analyses demonstrate that cyclin A1 exerts antiapoptotic functions by interacting with retinoblastoma and Ku proteins in leukemia cells.
16799873 The data implicate cyclin A1 as a downstream player in p53-dependent apoptosis and G2 arrest.
16007189 cyclin A1 mediates VEGF expression in cooperation with Rb- and androgen-dependent pathways in prostate cancer
15159402 study provides evidence that the cyclin A1-cyclin dependent kinase 2 complex plays a role in several signaling pathways important for cell cycle control and meiosis
12579332 CCNA1 had successive increases in its promoter activity during spermatgogensis in transgenic mice.
16449996 Significant tumour specific methylation of cyclin A1 promoter seen in oral sqmaous cell carcinoma
15342377 Cyclin A1 methylation was inversely related to p53 mutational status in primary tumors, and forced expression of cyclin A1 resulted in robust induction of wild-type p53 in HNSCC cell lines.
15456866 These findings establish a novel function for cyclin A1 and CDK2 in DNA double strand break repair following radiation damage.
12121569 the level of cyclin A1 mRNA expression predicts meiotic disorders during spermatogenesis
17098733 Mip/LIN-9 is required for the expression of B-Myb, and both proteins collaborate in the control of the cell cycle progression via the regulation of S phase and cyclin A, cyclin B, and CDK1
15829981 these analyses demonstrate that cyclin A1 contributes to G1 to S cell cycle progression in somatic cells.

 

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