Friday November 27 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

CDK5R2


Suggest Content
Advertise Here
Gene DB Home
Symbol:CDK5R2
Name(s):cyclin-dependent kinase 5, regulatory subunit 2 (p39)
Type:protein-coding
Organism:Homo sapiens
Synonyms:NCK5AI, P39, p39nck5ai
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11784720 Our data suggest that neurotoxic insults lead to calpain-mediated conversion of p39 to p29, which might contribute to deregulation of Cdk5
15917097 role of the CDK5 molecular complex in the genetic etiology of early-onset Alzheimer disease; a yet unknown functional variant in CDK5 or in a nearby gene might lead to increased susceptibility for early-onset Alzheimer disease

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDActinin alpha 1cyclin-dependent kinase 5, regulatory subunit 2--Pubmed
HPRDactinin, alpha 1Cyclin dependent kinase 5, regulatory subunit 2--Pubmed
HPRDCyclin dependent kinase 5cyclin-dependent kinase 5, regulatory subunit 2--Pubmed
HPRDcyclin-dependent kinase 5Cyclin dependent kinase 5, regulatory subunit 2--Pubmed

Recent Publications on CDK5R2:

Pubmed Logo
Identification of genes mediating thyroid hormone action in the developing mouse cerebellum.
Despite the indispensable role thyroid hormone (TH) plays in brain...
20th February, 2008
Laboratory of Molecular Neurobiology, Department of Chemistry and J Neurochem. 2008 Feb;104(3):640-52. Epub 2007 Nov 14.
DOI Direct Link
Association of cyclin-dependent kinase 5 and neuronal activators p35 and p39 complex in early-onset Alzheimer's disease.
Malfunctioning of cyclin-dependent kinase 5 (CDK5) through aberrant...
19th August, 2005
Department of Molecular Genetics, Flanders Interuniversity Institute for Neurobiol Aging. 2005 Aug-Sep;26(8):1145-51. Epub 2004 Dec 22.
DOI Direct Link

CDK5R2 results (if any) from reagent suppliers

Google CSE Logo
Abgent - Phosphorylation Antibodies - Phosphorylation
AP7743b, CDK5R1(p35) Antibody (C-term), IHC, E, H. AP7743a, CDK5R1(p35) Antibody (N-term), IHC, E, H. AP7742bNEW, CDK5R2(p39) Antibody (C-term), IHC, E, H ...
http://www.abgent.com/products/category/protein_modification...

Thumbshot
p39 (N-16) Antibody sc-18943
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, CDK5R2, 8941, 2q35, NM_003936 ...
http://www.scbt.com/datasheet-18943-p39-n-16-antibody.html...

Thumbshot
p39 (H-70) Antibody sc-28932
Spezies, Gen, Gen ID, Chromosomaler Locus, mRNA (Isoform) Accession #, Protein Accession #, OMIM™ Nummer. Human, CDK5R2, 8941, 2q35, NM_003936 · Q13319 ...
http://www.scbt.com/de/datasheet-28932-p39-h-70-antibody.htm...

Thumbshot
p39 (H-70) Antibody sc-28932
Humain, CDK5R2, 8941, 2q35, NM_003936 · Q13319 · 603764. Souris, Cdk5r2, 12570, 1 C3, O35926, Non disponible. Produits disponibles ...
http://www.scbt.com/fr/datasheet-28932-p39-h-70-antibody.htm...

Thumbshot
p39 (H-70) Antibody sc-28932
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, CDK5R2, 8941, 2q35, NM_003936 · Q13319
...
http://www.scbt.com/ja/datasheet-28932-p39-h-70-antibody.htm...

Thumbshot

Search Bioportfolio and other Life Science Sites for CDK5R2, or search for CDK5R2 on BioPortfolio's antibody search engine.
This page has been viewed 245 times
Recent Search Terms used to find this page:
p39 p29 antibody | information of cyclin-dependent kinase 5 regulatory subunits 2 p39 | cdk5r2 | antibody for cyclin-dependent kinase 5 regulatory subunit 1 | CYCLIN-DEPENDENT KINASE 5 REGULATORY SUBUNIT | p39 kinase | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.