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NAT1


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Symbol:NAT1
Name(s):N-acetyltransferase 1 (arylamine N-acetyltransferase)
Type:protein-coding
Organism:Homo sapiens
Synonyms:AAC1, NATI
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18199719 Sequence variants of NAT1 is associated with lung and aerodigestive tract cancers
18199719 Observational study of gene-disease association. (HuGE Navigator)
18207572 Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18258609 Observational study of gene-disease association. (HuGE Navigator)
18262724 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
18268115 Observational study of gene-disease association, gene-gene interaction, and gene-environment interaction. (HuGE Navigator)
18322880 Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
18069763 findings indicate an association between inflammation and suppression of NAT1 in cholangiocarcinoma cells, which perhaps contributes to chemical-mediated toxicity and carcinogenesis.
10791558 Meta-analysis and HuGE review of genotype prevalence, gene-disease association, gene-gene interaction, gene-environment interaction, and healthcare-related. (HuGE Navigator)
11034589 Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDN-acetyltransferase 1N-acetyltransferase ARD1--Pubmed
HPRDN-acetyltransferase 1ARD1--Pubmed

Recent Publications on NAT1:

Pubmed Logo
Isoform-Selective Inactivation of Human Arylamine N-Acetyltransferases by Reactive Metabolites of Carcinogenic Arylamines.
Human arylamine N-acetyltransferases (NATs) are expressed as two...
22nd October, 2009
Department of Medicinal Chemistry, University of Minnesota, 308 Harvard Chem Res Toxicol. 2009 Oct 20.
DOI Direct Link
Effects of genetic polymorphisms of N-Acetyltransferase on trichloroethylene-induced hypersensitivity dermatitis among exposed workers.
The hypersensitivity dermatitis induced by trichloroethylene (TCE)...
17th October, 2009
National Institute for Occupational Health and Poison Control, Chinese Ind Health. 2009 Oct;47(5):479-86.
Mechanisms and kinetics of human arylamine N-acetyltransferase 1 inhibition by disulfiram.
Disulfiram has been used for decades to treat alcoholism. Its therapeutic...
15th October, 2009
Universite Paris Diderot-Paris 7, Unite de Biologie Fonctionnelle et FEBS J. 2009 Sep;276(17):4900-8. Epub 2009 Jul 31.
DOI Direct Link
Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms, and colorectal cancer risk in the multiethnic cohort study.
BACKGROUND: N-acetyltransferases (NAT) 1 and 2 are polymorphic enzymes...
9th October, 2009
Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2098-106. Epub 2009 Jun
DOI Direct Link
Genetic variation in N-acetyltransferases 1 and 2, cigarette smoking, and risk of non-Hodgkin lymphoma.
Cigarette smoke contains many carcinogens that are metabolically activated...
8th October, 2009
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Cancer Causes Control. 2009 Oct 7.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Pharmacokinetic Study for Anti-tuberculosis Drugs

Patents:

Patents logo
US Patent No.Title
6985920 Method and system for determining intra-session event correlation across network address translation devices
7208274 Rapid analysis of variations in a genome
7208313 Combined growth factor-deleted and thymidine kinase-deleted vaccinia virus vector
7227872 Mechanisms for providing stateful NAT support in redundant and asymetric routing environments
7269157 System and method to assure network service levels with intelligent routing

View more patents.

NAT1 results (if any) from reagent suppliers

Google CSE Logo
NAT-1/2 (G-5) Antibody sc-137204
NAT-1 shRNA (h) Lentiviral Particles, sc-61154-V, 200 µl ... Western blot analysis of NAT-1/2 expression in HeLa whole cell lysate. Download ...
http://www.scbt.com/datasheet-137204-nat-1-2-g-5-antibody.ht...

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NAT1 antibodies: Signal Transduction > Metabolism > Amino Acids ...
NAT1 antibodies. ... NAT1 antibodies. Code. Name. Applications (see key) & Reactivity (see key). Image Abreview Publication. ab72734 · NAT1 antibody ...
http://www.abcam.com/index.html?t=270052&pt=1&c=712&ei=&mu=r...

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NAT-1/2 (C-16) Antibody sc-47219
goat polyclonal IgG, 200µg/ml; epitope mapping at the C-terminus of NAT-1 of human origin; recommended for detection of NAT-1 of human origin, ...
http://www.scbt.com/datasheet-47219-nat-1-2-c-16-antibody.ht...

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eIF4G Antibody #2498
The eIF4G family includes eIF4G1 (eIF4GI), eIF4G2 (p97, DAP5 or NAT1), and eIF4G3 (eIF4GII) (7). These factors share a homologous sequence that provides
for ...
http://www.cellsignal.com/products/2498.html...

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NAT-1/2 (C-12) Antibody sc-47226
NAT-1/2 (C-12) P, sc-47226 P (peptide), 100 µg/0.5 ml ... NAT-1 (h): 293T Lysate , sc-112994, 100µg/200µl, $195. NAT-2 (m): 293T Lysate, sc-121945 ...
http://www.scbt.com/ko/datasheet-47226-nat-1-2-c-12-antibody...

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Antibody Products - IgG Polyclonal Antibodies - GenWay
Rabbit polyclonal to DAP5; 1982; EIF4G2; 602325; P78344; AAG1; DAP5; NAT1; p97;; Eukaryotic translation initiation factor 4 gamma 2, IgG Polyclonal ...
http://www.genwaybio.com/all_polyclonal_antibodies.php?fl=D...

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NAT Antibody / NAT Antibodies
NAT-1/2 (C-16) 抗体, sc-47219, goat IgG, C-terminus (h), WB, IP, IF, ELISA, human ... NAT-1/2 (G-5) 抗体, sc-137204, mouse IgG1, C-terminal (h), WB, IP, IF,
...
http://www.scbt.com/ja/table-nat.html...

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