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TAF1C


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Symbol:TAF1C
Name(s):TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC:39976, SL1, TAFI110, TAFI95
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
16055704 PTEN represses RNA Pol I transcription through a novel mechanism that involves disruption of the SL1 complex
15970593 SL1 directs preinitiation complex formation, functioning in core promoter binding, RNA polymerase I recruitment, and UBF stabilization.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
BINDv-myc myelocytomatosis viral oncogene homolog-TAFI110 interacts with c-Myc.-Pubmed
HPRDTATA box binding proteinTBP-associated factor 1C isoform 1--Pubmed
HPRDTATA box binding proteinTAF1C--Pubmed
BINDTATA box binding proteinTBP-associated factor 1C isoform 1TBP interacts with TAFI110 within the SL1 transcription factor complex-Pubmed
HPRDtumor protein p53TBP-associated factor 1C isoform 1--Pubmed
HPRDtumor protein p53TBP-associated factor 1C isoform 1--Pubmed
BIND-RRN3 RNA polymerase I transcription factor homologTIF-IA interacts with TAFI95. This interaction was modeled on a demonstrated interaction between human TIF-IA and TAFI95 from an unspecified species.-Pubmed
HPRDTBP-associated factor 1C isoform 1TBP-associated factor 1B--Pubmed
HPRDTBP-associated factor 1C isoform 1TBP-associated factor 1B--Pubmed
BINDTBP-associated factor 1C isoform 1TBP-associated factor 1BTAFI110 interacts with TAFI63 within the SL1 transcription factor complex.-Pubmed

Recent Publications on TAF1C:

Pubmed Logo
Modifications of both selectivity factor and upstream binding factor contribute to poliovirus-mediated inhibition of RNA polymerase I transcription.
Soon after infection, poliovirus (PV) shuts off host-cell transcription,...
8th September, 2005
Department of Microbiology, Immunology and Molecular Genetics, University J Gen Virol. 2005 Aug;86(Pt 8):2315-22.
DOI Direct Link
Genomic localization of the human genes TAF1A, TAF1B and TAF1C, encoding TAF(I)48, TAF(I)63 and TAF(I)110 subunits of class I general transcription initiation factor SL1.
Human SL1 is a general transcription initiation factor (GTF) essential for...
12th August, 2000
Dipartimento di Scienze biomediche, Sezione di Biologia generale, Cytogenet Cell Genet. 2000;89(1-2):133-6.

Patents:

Patents logo
US Patent No.Title
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods

TAF1C results (if any) from reagent suppliers

Google CSE Logo
c-Myc antibody, c-Myc antibody (FITC) Antibody, Rabbit Polyclonal ...
Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with JARID1A and JARID1B. Subcellular Location: Nucleus. Ptm: Phosphorylated by PRKDC. ...
http://www.genwaybio.com/product_info.php?products_id=198425...

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TAF Basal Transcription Factor Antibody / TAF Basal Transcription ...
TAF Basal Transcription Factor Antibody / TAF Basal Transcription Factor Antibodies.
http://www.scbt.com/table-taf_basal_transcription_factor.htm...

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Abgent - Transcription and Regulation Antibodies ...
AT4144aNEW, TAF1C monoclonal antibody (M02), ELISA,WB-Re,WB-Tr, H. AT4147aNEW, TAF7 monoclonal antibody (M01), ELISA,IF,IHC-P,RNAi-Ab,S-ELISA,WB-Ce,WB-Re, H
...
http://www.abgent.com/products/category/nuclear_signaling/tr...

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TAF I p110 (h): 293T Lysate sc-114680
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, TAF1C, 9013, 16q24.1, Q15572 ...
http://www.scbt.com/datasheet-114680-taf-i-p110-h-293t-lysat...

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Abcam antibodies and reagents product map
... TAF1 48 antibodies (3) · TAF1B antibodies (2) · TAF1C antibodies (2) · UBF1 antibodies (3) · UBTFL1 antibodies (1) · ZNDR1 antibodies (1) ...
http://www.abcam.com/index.html?c=250...

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TAF I p110 (C-18) Antibody sc-6566
Species, 遺伝子名, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. ヒト, TAF1C, 9013, 16q24.1, NM_005679, ...
http://www.scbt.com/ja/datasheet-6566-taf-i-p110-c-18-antibo...

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TAF I p110 (C-18) Antibody sc-6566
... Numéro d'accès d´isoforme d´ARNm, Numéro d'accès de la protéine, Numéro OMIM ™. Humain, TAF1C, 9013, 16q24.1, NM_005679, NM_139353 · Q15572 ...
http://www.scbt.com/fr/datasheet-6566-taf-i-p110-c-18-antibo...

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