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UBA3
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 12740388 |
Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer. |
| 12646924 |
structure and mutational analysis of human APPBP1-UBA3, the heterodimeric E1 enzyme for NEDD8 |
| 15694336 |
crystal structure of a complex between the C-terminal domain from NEDD8's heterodimeric E1 (APPBP1-UBA3) and the catalytic core domain of NEDD8's E2 (Ubc12) |
| 14690597 |
Data report the structure of the quaternary complex between human APPBP1-UBA3, a heterodimeric E1, its ubl NEDD8, and ATP. |
Recent Publications on UBA3: |  |
The mechanism of poly-NEDD8 chain formation in vitro.
NEDD8 is a small ubiquitin-like protein that modifies target proteins in a... | 17th April, 2009
| Department of Molecular Biology, Graduate School of Life and Environmental
| Biochem Biophys Res Commun. 2009 Apr 10;381(3):443-7. Epub 2009 Feb 24.
DOI Direct Link |
SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
Covalent modification of cullins by the ubiquitin-like protein NEDD8... | 30th January, 2009
| Department of Surgery, Laboratory of Epithelial Cancer Biology, Memorial
| J Biol Chem. 2008 Nov 28;283(48):33211-20. Epub 2008 Sep 30.
DOI Direct Link |
Structural dissection of a gating mechanism preventing misactivation of ubiquitin by NEDD8's E1.
Post-translational covalent modification by ubiquitin and ubiquitin-like... | 10th September, 2008
| Department of Structural Biology, St. Jude Children's Research Hospital,
| Biochemistry. 2008 Aug 26;47(34):8961-9. Epub 2008 Jul 25.
DOI Direct Link |
TRIP12 functions as an E3 ubiquitin ligase of APP-BP1.
The NEDD8 pathway plays an essential role in various physiological... | 22nd August, 2008
| Department of Biochemistry and Protein Network Research Center, Yonsei
| Biochem Biophys Res Commun. 2008 Sep 19;374(2):294-8. Epub 2008 Jul 15.
DOI Direct Link |
Basis for a ubiquitin-like protein thioester switch toggling E1-E2 affinity.
Ubiquitin-like proteins (UBLs) are conjugated by dynamic E1-E2-E3 enzyme... | 21st February, 2007
| Howard Hughes Medical Institute, St Jude Children's Research Hospital,
| Nature. 2007 Jan 25;445(7126):394-8. Epub 2007 Jan 14.
DOI Direct Link |
→View more research publications. |
UBA3 results (if any) from reagent suppliers | 
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UBA3 (E-22) Antibody sc-130905
UBA3 (E-22): sc-130905. Immunoperoxidase staining of formalin-fixed, ... Western blot analysis of UBA3 expression in mouse brain tissue extract. Download ...
http://www.scbt.com/datasheet-130905-uba3-e-22-antibody.html...
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NEDD8 Antibody #2745
Mature NEDD8 is then covalently linked to target proteins via the carboxy- terminal glycine residue in a reaction catalyzed by the APP-BP1/Uba3 heterodimer
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http://www.cellsignal.com/products/2745.html...
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Uba Antibody / Uba Antibodies
UBA3 (N-18) Antibody, sc-79800, goat IgG, N-terminal (h), WB, IP, IF, ELISA, m, r, h, cow. Uba3 (yN-19) Antibody, sc-8932, goat IgG, N-terminus (Sc) ...
http://www.scbt.com/table-uba.html...
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NEDD8 Antibody
by the APP-BP1/Uba3 heterodimer complex and Ubc12 as the E1- and E2-like enzymes , respectively (5). An E3 ligase protein, Roc1/Rbx1, is also required for ...
http://www.cellsignal.com/pdf/2745.pdf...
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UBA3 (E-22) Antibody sc-130905
UBA3 (E-22) Antikörper sc-130905 UBA3 (E-22) Antibody sc-130905.
http://www.scbt.com/de/datasheet-130905-uba3-e-22-antibody.h...
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NEDD8 (19E3) Rabbit mAb
cine residue in a reaction catalyzed by the APP-BP1/Uba3 heterodimer complex and Ubc12 as the E1- and E2-like enzymes, respectively (5). ...
http://www.cellsignal.com/pdf/2754.pdf...
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Product name(s): Catalogue number: Batch number: Expiry date: 1 ...
Uba3), E2 conjugating enzyme (UbcH12) and substrate specific E3 ligases2,3. An increasing number of substrates for NEDDylation, including the tumor ...
http://www.biomol.com/SiteData/docs/productdata/UW0590.pdf...
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