Tuesday November 24 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

CD1A


Suggest Content
Advertise Here
Gene DB Home
Symbol:CD1A
Name(s):CD1a molecule
Type:protein-coding
Organism:Homo sapiens
Synonyms:CD1, FCB6, HTA1, R4, T6
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18251780 CD1a expression can be an additional new marker for PEComas and also supports the distinct and integrated disease entity of PEComas.
18178838 These findings identify Ii and lipid rafts as key regulators of CD1a organization on the surface of immature DCs and of its immunological function as Ag-presenting molecule.
11580851 Observational study of gene-disease association. (HuGE Navigator)
16820217 Observational study of gene-disease association. (HuGE Navigator)
17428545 Observational study of gene-disease association. (HuGE Navigator)
18184269 The positive and significant correlations between the number of CD1a+ cells and positivity of the primary tumour for estrogen receptor and progesterone receptor suggest a possible role for CD1a as a prognostic marker for breast cancer.
17652534 In cystic teratomas of the ovary, CD1-positive Langerhans cells appeared to cross the basal membrane and penetrate the subepidermal tissue, and they were associated there with T-cell line lymphocytes (CD3 positive).
17428545 Associated with chronic dysimmune neuropathies
15099564 Review. CD1a on tumor-infiltrating dendritic cells may present immunogenic tumor-specific glycolipid antigens to T-cells.
16598657 In this study, we show that PTX can selectively block the expression of CD1a isoform during the differentiation of human monocytes into dendritic cells.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDbeta-2-microglobulin precursorCD1A antigen precursor--Pubmed
HPRDbeta-2-microglobulin precursorCD1A antigen precursor--Pubmed

Recent Publications on CD1A:

Pubmed Logo
Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids.
Dendritic cells (DCs) are the key cell type in the regulation of an...
30th October, 2009
Institute of Immunology, Medical University Vienna, Austria; Blood. 2009 Oct 28.
DOI Direct Link
Bone marrow findings at diagnosis in patients with multisystem Langerhans' cell histiocytosis.
Abstract Objectives: This study was designed to describe the bone marrow...
30th October, 2009
1 Hospital Nacional de Pediatria Dr Prof. J.P Garrahan. Pediatr Dev Pathol. 2009 Oct 19.
DOI Direct Link
Presentation of lipid antigens by CD1 glycoproteins.
CD1 molecules are a family of non-polymorphic, class I antigen-presenting...
29th October, 2009
Department of Molecular Biology, Skaggs Institute for Chemical Biology, Curr Pharm Des. 2009;15(28):3311-7.
About the cutaneous targets of bexarotene in CTCL patients.
Please cite this paper as: About the cutaneous targets of bexarotene in...
23rd October, 2009
INSERM, U892, Nantes Cedex 01, France. Exp Dermatol. 2009 Oct 21.
DOI Direct Link
Histiocytic sarcoma with interdigitating dendritic cell differentiation: A case report with fine needle aspiration cytology and review of literature.
A hybrid histiocytic sarcoma-interdigitating dendritic cell sarcoma was...
22nd October, 2009
Department of Pathology and Laboratory Medicine, Weill Medical College of Diagn Cytopathol. 2009 Oct 20.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Generation of Dendritic Cell Precursors From Cord Blood Stem Cells

Patents:

Patents logo
US Patent No.Title
7341870 Dendritic cell line
7399464 Polypeptides of the IFN.alpha.-7 gene
7402305 Polypeptides of the IFN.alpha.-21 gene
7405076 Generation and use of dendritic cells
7413869 Method for determining potency of antigenic presenting cell based vaccines

View more patents.

CD1A results (if any) from reagent suppliers

Google CSE Logo
CD1a antibody (ab27453) | Abcam
Rabbit polyclonal to CD1a. CD1a is a non polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 microglobulin.
http://www.abcam.com/CD1a-antibody-ab27453.html...

Thumbshot
PE/Cy5 Anti-human CD1a Antibody Anti-CD1a - BioLegend
PE/Cy5 Anti-human CD1a Antibody Anti-CD1a - CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4.
http://www.biolegend.com/pe-cy5-anti-human-cd1a-antibody-702...

Thumbshot
human CD1a antibody, Fluorescein isothiocyanate (FITC) conjugate
eBioscience technical data sheet for product 11-0019 FITC anti-human CD1a HI149 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_11/11-...

Thumbshot
CD1A (HI149) Antibody sc-19636
CD1A (HI149) Alexa Fluor® 488, sc-19636 AF488, 100 µg/ 2 ml, $299. CD1A (HI149) Alexa Fluor® ... CD1A (HI149) PE: sc-19636 PE. FCM analysis of MOLT-4 cells. ...
http://www.scbt.com/datasheet-19636-cd1a-hi149-antibody.html...

Thumbshot
CD1a antibody [NA1/34-HLK] (ab24055) | Abcam
Mouse monoclonal [NA1/34-HLK] to CD1a. CD1a is a non polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta 2 ...
http://www.abcam.com/CD1a-antibody-NA1-34-HLK-ab24055.html...

Thumbshot
CD1A (O10) Antibody sc-18885
CD1A shRNA (h) Lentiviral Particles, sc-42744-V, 200 µl ... See how others have used CD1A (O10): sc-18885 antibody and or CD1A (O10) antibody conjugates. ...
http://www.scbt.com/datasheet-18885-cd1a-o10-antibody.html...

Thumbshot
The Abcam catalog
CD1a antibodies. ... CD1a antibody [HI149] (Allophycocyanin). Flow Cyt. Mouse monoclonal ... CD1a antibody [JPM30]. IHC-P, IHC-Fr. Mouse monoclonal ...
http://www.abcam.com/index.html?t=2863&pt=1&c=499...

Thumbshot

Search Bioportfolio and other Life Science Sites for CD1A, or search for CD1A on BioPortfolio's antibody search engine.
This page has been viewed 516 times
Recent Search Terms used to find this page:
xhanster | Datasheet CD1a | CD1a | cd1a | CD1a | CD1a | CD1a | cd1a molecule | CD1a | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.