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CD1C


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Gene DB Home
Symbol:CD1C
Name(s):CD1c molecule
Type:protein-coding
Organism:Homo sapiens
Synonyms:BDCA1, CD1, CD1A, R7
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
11580851 Observational study of gene-disease association. (HuGE Navigator)
15556687 CD1c expression was detected on monocytes in the majority of sickle cell anemia patients, and was highly expressed in Sbeta thalassemia patients.
14551186 CD1b and CD1c show strong binding of nitrobenzoxadiazole (NBD)-labeled dialkyl-based ligands.
15749918 hypothesis that CD1-restricted T cells might be activated and home to target tissues involved in Hashimoto's thyroiditis and Graves' disease
16272286 identified CD1a-, CD1b-, and CD1c-restricted T cells from normal human donors that induce cytolysis and secrete copious IFN-gamma in response to self-CD1 expressed on monocyte-derived dendritic cells
12454749 B cell chronic lymphocytic leukemia cells significantly down-regulated transcripts from CD1c and CD1d genes, permitting cells to evade the immune response

Recent Publications on CD1C:

Pubmed Logo
Epigenetic regulation of dendritic cell differentiation and function by oxidized phospholipids.
Dendritic cells (DCs) are the key cell type in the regulation of an...
30th October, 2009
Institute of Immunology, Medical University Vienna, Austria; Blood. 2009 Oct 28.
DOI Direct Link
Presentation of lipid antigens by CD1 glycoproteins.
CD1 molecules are a family of non-polymorphic, class I antigen-presenting...
29th October, 2009
Department of Molecular Biology, Skaggs Institute for Chemical Biology, Curr Pharm Des. 2009;15(28):3311-7.
Efficacy of bacille Calmette-Guerin immunotherapy predicted by expression of antigen-presenting molecules and chemokines.
OBJECTIVES: To ascertain the role and prognostic value of...
24th October, 2009
Departamento de Imunologia, Faculdade de Ciencias Medicas de Lisboa, Campo Urology. 2009 Oct;74(4):944-50. Epub 2009 May 9.
DOI Direct Link
Predicted structural basis for CD1c presentation of mycobacterial branched polyketides and long lipopeptide antigens.
CD1 proteins mediate the trafficking and presentation of a diverse range...
16th October, 2009
Theoretical Molecular Biophysics Group, Max Planck Institute of Mol Immunol. 2009 Oct 12.
DOI Direct Link
Adoptive immunotherapy mediated by ex vivo expanded natural killer T cells against CD1d-expressing lymphoid neoplasms.
BACKGROUND: CD1d is a monomorphic antigen presentation molecule expressed...
14th October, 2009
Human Anatomy Section, Department of Experimental Medicine, University of Haematologica. 2009 Jul;94(7):967-74. Epub 2009 May 19.
DOI Direct Link

View more research publications.

Clinical Trials:

Clinical Trials Logo
Narrowband UVB Phototherapy in the Treatment of Psoriasis Vulgaris

Patents:

Patents logo
US Patent No.Title
6399763 Method for producing antibody fragments
6673908 Tumor necrosis factor receptor 2
6687727 Method and apparatus for arithmetic operation and recording medium of method of operation
6687728 Method and apparatus for arithmetic operation and recording medium of method of operation
6747010 NKT cell-activating agents containing .alpha.-glycosylceramides

View more patents.

CD1C results (if any) from reagent suppliers

Google CSE Logo
Pacific Blue Anti-human CD1c Antibody Anti-CD1c - BioLegend
Pacific Blue Anti-human CD1c Antibody Anti-CD1c - CD1c, known as R7 or M241, is a 43 kD member of the five CD1 antigens (CD1a-e) in human.
http://www.biolegend.com/pacific-blue-anti-human-cd1c-antibo...

Thumbshot
anti-CD1c
Three of the gene products (CD1a, CD1b and CD1c) have been officially clustered using antibodies and are expressed on cortical thymocytes, ...
http://www.ancell.com/html/anti-cd1c.html...

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CD1C (L161) Antibody sc-18886
mouse monoclonal IgG1; 200 µg/ml; raised against thymus cells; recommended for detection of CD1C of human origin by IP, IF and FCM; fluorescein (sc-18886 ...
http://www.scbt.com/datasheet-18886-cd1c-l161-antibody.html...

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human CD1 antibody, Fluorescein isothiocyanate (FITC) conjugate
CD1c is involved in the presentation of lipid antigens such as microbial fatty ... Human CD1b and CD1c isoforms survey different intracellular compartments ...
http://www.ebioscience.com/ebioscience/specs/antibody_11/11-...

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CD1 Antibody / CD1 Antibodies
CD1C (M241) Antibody, sc-53192, mouse IgG1, FL (h), IP, human. CD1D (C3D5) Antibody, sc-19632 ... CD1C shRNA (h) Lentiviral Particles: sc-42746-V ...
http://www.scbt.com/table-cd1.html...

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Human CD Molecules, Cd Related Molecules - BioLegend
CD1c · CD195 (CCR5) · CD2 (LFA-2) · CD195 (CCR5) Phosphorylated (Ser337) ..... Alexa Fluor® 647 Anti-human CD1c Antibody, L161, FC ...
http://www.biolegend.com/immunology-5321/human-immunology-15...

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CD1C (L161) Antibody sc-18886
CD1C (L161) Antikörper sc-18886 CD1C (L161) Antibody sc-18886.
http://www.scbt.com/de/datasheet-18886-cd1c-l161-antibody.ht...

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