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UBE2L6


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Symbol:UBE2L6
Name(s):ubiquitin-conjugating enzyme E2L 6
Type:protein-coding
Organism:Homo sapiens
Synonyms:MGC40331, RIG-B, UBCH8
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15670748 Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 knockdown, respectively.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDparkin isoform 1ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDparkin isoform 1ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDseven in absentia homolog 2ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDseven in absentia homolog 2ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
BINDubiquitin protein ligase E3A isoform 2ubiquitin-conjugating enzyme E2L 6 isoform 1UbcH8 interacts with E6AP.-Pubmed
HPRDubiquitin protein ligase E3A isoform 2ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDubiquitin protein ligase E3A isoform 2ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDZinc finger protein 147ubiquitin-conjugating enzyme E2L 6 isoform 1--Pubmed
HPRDtripartite motif-containing 25Ubiquitin conjugating enzyme E2L6--Pubmed
HPRDUbiquitin conjugating enzyme E2L6ring finger protein 40--Pubmed

Recent Publications on UBE2L6:

Pubmed Logo
Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.
Dendritic cell maturation is the process by which immature dendritic cells...
14th August, 2009
Charite-Universitatsmedizin Berlin, CCM, Institut fur Biochemie, Int J Biochem Cell Biol. 2009 May;41(5):1205-15. Epub 2008 Nov 5.
DOI Direct Link
[Regulation of immune response by ubiquitin-like molecule ISG15]
Mucin hypersecretion is considered to be one of the most common components...
26th June, 2009
Department of Biochemistry, Graduate School of Medicine, Hokkaido Seikagaku. 2009 Mar;81(3):223-32.
ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway.
Interferon (IFN)-induced signalling pathways have essential functions in...
19th June, 2009
School of Biological Sciences, Seoul National University, 56-1 EMBO Rep. 2009 Apr;10(4):374-80. Epub 2009 Mar 6.
DOI Direct Link
Interferon-induced ISG15 conjugation inhibits influenza A virus gene expression and replication in human cells.
The ubiquitin-like ISG15 protein, as well as its conjugating enzymes, is...
29th May, 2009
Institute for Cellular and Molecular Biology, University of Texas at J Virol. 2009 Jun;83(12):5971-7. Epub 2009 Apr 8.
DOI Direct Link
Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme.
ISG15 is a ubiquitin-like protein that is upregulated on treatment with...
25th April, 2009
Department of Biochemistry, Graduate School of Pharmaceutical Sciences, J Biochem. 2005 Dec;138(6):711-9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
6919184 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
6979551 Assays for identifying ubiquitin agents and for identifying agents that modify the activity of ubiquitin agents
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
7132234 Methods and compositions for the identification of anti-poxvirus agents

View more patents.

UBE2L6 results (if any) from reagent suppliers

Google CSE Logo
UBE2L6 Antibody (N-term)
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with UBE2L6 Antibody (N-term)(Cat.#AP2118a), which was peroxidase-conjugated to the ...
http://www.abgent.com/products/catalog_no/AP2118a_UBE2L6_Ant...

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Ube2L6 antibodies: Cell Biology > Proteolysis / Ubiquitin ...
Ube2L6 antibodies. ... Ube2L6 antibody - N-terminal. IHC-P, WB, ELISA. Images · Specific publication references. Rabbit polyclonal ...
http://www.abcam.com/index.html?t=14171&pt=1&c=1039&ei=&mu=r...

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Protein Modification - Ubiquitination Antibody
AT4439aNEW, UBE2L3 monoclonal antibody (M01), ELISA,IF,S-ELISA,WB-Ce,WB-Re, H. AP2118b, UBE2L6 Antibody (C-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/protein_modification...

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Ube2L6 proteins and peptides: Cell Biology > Proteolysis ...
Ube2L6 proteins and peptides. ... Applications (see key) & Reactivity (see key). Image Abreview Publication. ab79192 · Ube2L6 protein (His tag). SDS-PAGE ...
http://www.abcam.com/index.html?t=14171&pt=2&c=1039&ei=&mu=r...

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Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE2L6 C-term Antibody. AP2133b. USP4 C-term Antibody. AP2162a. AMFR N-term Antibody ... UBE2L6 N-term Antibody. AP2134b. USP5 C-term Antibody. AP2168b ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

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View Cart
UBE2L6 Antibody (C-term) Blocking Peptide, BP2118b, 0.1mg, $42.00, $42.00. Shipping, flat fee, $40.00. Tax will be added to the Total after the order is
...
https://www.abgent.com/store/add_to_cart/BP2118b...

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Citations
UBE2L6 Antibody (N-term). Mohammad Shahidul Makki, et al. TSA downregulates Wilms tumor gene 1 (Wt1) ... UBE2L6 Antibody (C-term). Kramer, Oliver H., et al.
...
http://www.abgent.com/docs/citation...

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