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ACVR2B
Gene Information from Publications |
| Publication Link |
Summary of findings |
| 17893364 |
The high-resolution structure of human ActRIIB kinase domain in complex with adenine establishes the conserved bilobal architecture consistent with all other catalytic kinase domains. |
| 17347381 |
These results indicate that haplotype structure at the ACVR2B and follistatin loci may contribute to interindividual variation in skeletal muscle mass and strength, although these data indicate sex-specific relationships. |
| 14738881 |
Data indicate that activin A and activin receptors IIA and IIB may be involved in the regulation of germ cell proliferation in the human ovary during the period leading up to primordial follicle formation. |
| 15123686 |
activin signaling via type II receptors requires a specific sequence for ALK4 binding |
| 12782414 |
analysis of expression and cellular compartmentalization of the activin receptors ActRIIA, ActRIIB and ActRIB, the inhibin co-receptor (betaglycan), and activin signaling proteins Smads 2, 3 and 4, and growth regulatory role during lactation |
| 11969340 |
distribution in gestational tissues across human pregnancy and during labour |
Interacting gene products |
| Interaction Type |
Gene 1 |
Gene 2 |
Interaction description |
Complex |
Publication Link |
| HPRD | Activin receptor like kinase 4 | activin A type IIB receptor precursor | - | - | Pubmed |
| HPRD | activin A type IB receptor isoform a precursor | Activin A receptor, type IIB | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | growth differentiation factor 5 preproprotein | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | bone morphogenetic protein 7 precursor | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | inhibin beta A precursor | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | inhibin beta B subunit precursor | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | transforming growth factor, beta receptor associated protein 1 | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | myostatin | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | inhibin beta C chain preproprotein | - | - | Pubmed |
| HPRD | Activin A receptor, type IIB | growth differentiation factor 11 | - | - | Pubmed |
Recent Publications on ACVR2B: |  |
Effects of Endogenous Growth Differentiation Factor 9 on Activin A-Induced Inhibin B Production in Human Granulosa-Lutein Cells.
Background: We recently reported on the effects of exogenous growth... | 23rd October, 2009
| Department of Obstetrics and Gynaecology, Child and Family Research
| J Clin Endocrinol Metab. 2009 Oct 21.
DOI Direct Link |
Growth differentiation factor 9 enhances activin a-induced inhibin B production in human granulosa cells.
Activin A or growth differentiation factor 9 (GDF9) alone can increase... | 6th August, 2009
| Department of Obstetrics and Gynaecology, Child and Family Research
| Endocrinology. 2009 Aug;150(8):3540-6. Epub 2009 May 7.
DOI Direct Link |
Identification of tumor-associated autoantigens for the diagnosis of colorectal cancer in serum using high density protein microarrays.
There is a mounting evidence of the existence of autoantibodies associated... | 30th July, 2009
| Centro de Investigaciones Biologicas-Consejo Superior de Investigaciones
| Mol Cell Proteomics. 2009 Oct;8(10):2382-95. Epub 2009 Jul 28.
DOI Direct Link |
Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation.
Estrogen is involved in the development and progression of breast cancer.... | 11th July, 2009
| Department of Cancer and Thoracic Surgery, Okayama University Graduate
| J Endocrinol. 2008 Dec;199(3):445-55. Epub 2008 Sep 9.
DOI Direct Link |
Body surface area prediction in normal, hypermuscular, and obese mice.
BACKGROUND: Accurate determination of body surface area (BSA) in... | 30th May, 2009
| Division of Surgical Oncology, University of Miami Miller School of
| J Surg Res. 2009 May 15;153(2):326-31. Epub 2008 Jun 4.
DOI Direct Link |
→View more research publications. |
ACVR2B results (if any) from reagent suppliers | 
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ACVR2B Antibody (N-term)
Western blot analysis of anti-ACVR2B Antibody (N-term) (Cat. #AP7105a) in mouse heart, kidney and brain lysates (35ug/lane). ACVR2B (arrow) was detected ...
http://www.abgent.com/products/catalog_no/AP7105a_ACVR2B_Ant...
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Activin receptor type IIB antibody, Activin receptor type IIB ...
Goat polyclonal to Activin Receptor Type IIB; 93; ACVR2B; 602730; Q13705; ActR- IIB; MGC116908;; Activin receptor type-2B, AVR2B_HUMAN.
http://www.genwaybio.com/product_info.php?products_id=195153...
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Abgent - Phosphorylation Antibodies - Phosphorylation
AP7105a, ACVR2B Antibody (N-term), WB, IHC, E, H .... AP7105b, Activin Receptor Type IIB (ACVR2B) Antibody (C-term V474), WB, E, H ...
http://www.abgent.com/products/category/protein_modification...
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ACTR-IIB (N-16) Antibody sc-5665
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIM™ Number. Human, ACVR2B, 93, 3p22.2, NM_001106 ...
http://www.scbt.com/datasheet-5665-actr-iib-n-16-antibody.ht...
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Abgent - Cell and Function Antibodies
AP7102cNEW, ACVR1C Antibody (Center E271), WB, E, H. AP7103a, ACVR2A Antibody (N -term), WB, IHC, E, H. AP7105a, ACVR2B Antibody (N-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/cell_function...
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ACTR-II (D-15) Antibody sc-5669
Human, ACVR2B, 93, 3p22.2, NM_001106 · Q13705 · 602730. Mouse, Acvr2a, 11480, 2 C1.1, P27038 ... Mouse, Acvr2b, 11481, 9 F3, P27040 ...
http://www.scbt.com/ko/datasheet-5669-actr-ii-d-15-antibody....
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New Products and Services for Drug Discovery
ACVR2B is a type II member of the TGF-beta family of receptor ser/thr kinases and ... ACVR2B. LRRK2 is a multidomain protein that includes a kinase domain,
...
http://www.invitrogen.com/site/us/en/home/Products-and-Servi...
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