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UBE4A


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Symbol:UBE4A
Name(s):ubiquitination factor E4A (UFD2 homolog, yeast)
Type:protein-coding
Organism:Homo sapiens
Synonyms:E4, KIAA0126, MGC133315, UBOX2, UFD2
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
15611659 In these studies, we define Ufd2 (a novel E4 polyubiquitylating enzyme) as a new autoantigen in scleroderma, and show that it regulates chromosome condensation and separation during mitosis in human cells.
15019985 UBE4A is expressed in different tissues in a pattern that seems to be dependent from cell type and cell cycle and that UBE4A might have a specific role in different biochemical processes other than ubiquitination, including growth or differentiation.

Recent Publications on UBE4A:

Pubmed Logo
[Differential expression of USP2, USP14 and UBE4A between ovarian serous cystadenocarcinoma and adjacent normal tissues]
AIM: The differential expression of USP2, USP14 and UBE4A between ovarian...
1st May, 2009
Department of Anatomy, West China School of Preclinical and Forensic Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2007 Jun;23(6):504-6.
New serological biomarkers of inflammatory bowel disease.
Serological biomarkers in inflammatory bowel disease (IBD) are a rapidly...
19th December, 2008
Division of Gastroenterology, Department of Medicine, Johns Hopkins World J Gastroenterol. 2008 Sep 7;14(33):5115-24.
Autoantibodies against ubiquitination factor E4A (UBE4A) are associated with severity of Crohn's disease.
BACKGROUND: Identification of a disease- and organ-specific autoantigen...
16th May, 2008
Department of Digestive and Life-style Related Diseases, Kagoshima Inflamm Bowel Dis. 2008 Mar;14(3):310-7.
DOI Direct Link
Differentially expressed genes between high-risk human papillomavirus types in human cervical cancer cells.
Cervical carcinoma (CC) is one of the most common cancers among women...
16th May, 2007
Laboratory of Oncogenomics, Oncology Research Unit, Oncology Hospital, Int J Gynecol Cancer. 2007 Mar-Apr;17(2):484-91. Epub 2007 Feb 14.
DOI Direct Link
The two human homologues of yeast UFD2 ubiquitination factor, UBE4A and UBE4B, are located in common neuroblastoma deletion regions and are subject to mutations in tumours.
Chromosomes 11q and 1p are commonly deleted in advanced-stage...
10th March, 2006
Department of Clinical Genetics, Institute for the Health of Women and Eur J Cancer. 2006 Feb;42(3):381-7. Epub 2006 Jan 4.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7547687 Therapeutic treatment methods
7482334 Therapeutic treatment methods

UBE4A results (if any) from reagent suppliers

Google CSE Logo
UBE4A Antibody (N-term)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human UBE4A. Other
Names: ...
http://www.abgent.com/products/catalog_no/AP2110a_UBE4A_Anti...

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Ube4a antibodies: Cell Biology > Proteolysis / Ubiquitin ...
Ube4a antibodies. ... Ube4a antibody. WB. Rabbit polyclonal. Reacts with: Hu. ab56483 · Ube4a antibody. WB. Images. Mouse monoclonal. Reacts with: ...
http://www.abcam.com/index.html?t=79672&pt=1&c=1017&ei=&mu=r...

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Protein Modification - Ubiquitination Antibody
AP2110b, UBE4A Antibody (C-term), WB, IHC, E, H. AP2110a, UBE4A Antibody (N-term ), E, H. AT4446aNEW, UBE4A monoclonal antibody (M08), ELISA,S-ELISA,WB-Re, H ...
http://www.abgent.com/products/category/protein_modification...

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UBE4A siRNA (m) sc-63182
Click here for details. suitable control antibody: UBE4A (N-15): sc-54478; sqRT- PCR Primer also available: UBE4A (m)-PR: sc-63182, 20 µl ...
http://www.scbt.com/ko/datasheet-63182-ube4a-sirna-m.html...

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Ubiquitin (Ub) is a 76 amino acid highly conserved eukaryotic ...
UBE4A C-term Antibody. AP2138b. USP10 C-term Antibody. AP2101c. EDD Center Antibody ... UBE4A N-term Antibody. AP2138a. USP10 N-term Antibody. AP2101b ...
http://www.abgent.com/downloads/Ubiquitination.pdf...

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UBE Antibody / UBE Antibodies
UBE4A (G-20) 抗体, sc-54554, goat IgG, Internal (h), WB, IP, IF, ELISA, m, r, h ..... UBE4A shRNA Plasmid (m): sc-63182-SH. UBE4A shRNA (m) ...
http://www.scbt.com/ja/table-ube.html...

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Abgent Antibodies and Peptides
AP1336a, TrxL Antibody (N-term), H. AP2122b, UBE2H Antibody (C-term), H. AP2156b , UBE2V Antibody (C-term), H. AP2110a, UBE4A Antibody (N-term), H ...
http://www.abgent.com/docs/product_investigation...

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