Friday November 27 2009 | Biotechnology feed | All feeds

BioPortfolio Biotechnology Pharmaceutical Healthcare Medical Life Science Drug Discovery Disease

MUC16


Suggest Content
Advertise Here
Gene DB Home
Symbol:MUC16
Name(s):mucin 16, cell surface associated
Type:protein-coding
Organism:Homo sapiens
Synonyms:CA125, FLJ14303
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17942799 These data indicate that MUC16 is a membrane component of the nonreceptive luminal uterine surface, which prevents cell adhesion, and that its removal during uterodome formation facilitates adhesion of the trophoblast.
18042071 The frequency of expression of Ca125...in invasive micropapillary carcinomas...was similar to the results in unselected mammary carcinoma.
17852813 Results show that measurements of AFP, CEA and CA125 are more readily affected by long-term frozen storage compared with frequent freezing-thawing.
17604678 MUC16 is the major [(35)S]sulphate-labelled mucin in normal human bronchial epithelial cell secretions.
17852076 Measurement of CA 15-3 serum values in conjunction with sHER2 and CA 15-3 can increase sensitivity in metastasis detection.
17449138 Overall survival was closely related with the 4-week CA125 tumor marker response.
17285443 This is th e first study to show that serum CA 125 is related to the presence and severity of heart failure and diastolic dysfunction in hypertrophic cardiomyopathy.
17592322 This study shows that MUC1, MUC4, and MUC16 are regulated differently by dexamethasone in human corneal epithelial cells.
14676194 might contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to mesothelin
15599662 results showed the cell surface expression of CA125 in both adenocarcinoma and large cell carcinoma cell lines and the production of CA125 in culture medium

View more information from publications.

Patents:

Patents logo
US Patent No.Title
7612180 Humanized L243 antibodies
7341721 .beta..sub.2-microglobulin (.beta..sub.2m) and anti-.beta..sub.2m binding agents as anti-cancer therapeutics
7309760 Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions
7205142 Nucleic acid sequence encoding ovarian antigen, CA125, and uses thereof
7202346 Antibodies to non-shed Muc1 and Muc16, and uses thereof

View more patents.

MUC16 results (if any) from reagent suppliers

Google CSE Logo
MUC16 antibody [X325] (ab10033) | Abcam
Mouse monoclonal [X325] to MUC16. MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer.
http://www.abcam.com/MUC16-antibody-X325-ab10033.html...

Thumbshot
Product Specification Sheet
MUC16/CA125, and that this interaction mediates cell adhesion, suggesting that there may be an important role for MUC16/CA125 and mesothelin in the ...
http://www.rockland-inc.com/objects/catalog/product/extras/1...

Thumbshot
MUC16 antibodies: Cancer > Invasion/microenvironment > ECM ...
MUC16 antibodies. ... MUC16 (di methyl) antibody [X75]. Flow Cyt, WB, IHC-P ... MUC16 antibody [10G12]. WB, ELISA, IHC-Fr. Mouse monoclonal ...
http://www.abcam.com/index.html?t=55631&pt=1&c=4266&ei=&mu=r...

Thumbshot
Concentrated and Prediluted Monoclonal Antibody
alone and in combination with MUC1 and MUC16 (CA125). Mod Pathol. 2006 Jul 28;. 3. Rakha EA, Boyce RW, Abd El-Rehim D, Kurien T, Green AR, Paish EC, ...
http://www.biocare.net/antibody-datasheets/319.pdf...

Thumbshot
Antibody Products - IgG Monoclonal Antibodies - GenWay
MUC16; CA125 - MOUSE ANTI OVARIAN TUMOR MARKER; Mucin-16, IgG Monoclonal IHC-F, ELISA, WB, Source: Mouse Reactivity: N/A ...
http://www.genwaybio.com/all_monoclonal_antibodies.php?fl=O...

Thumbshot
Mucin 16 (X325) Antibody sc-52096
Species, Gene Name, Gene ID, Chromosome Location, Isoform (mRNA) Accession #, Protein Accession #, OMIMâ„¢ Number. Human, MUC16, 94025, 19p13.2, NM_024690 ...
http://www.scbt.com/datasheet-52096-mucin-16-x325-antibody.h...

Thumbshot
Cancer Biomarkers - R&D Systems
CA125/MUC16 · Herstatin · ErbB2/Her2 · Kallikrein 3/PSA · ER alpha/NR3A1 · Progesterone R/NR3C3. Putative Cancer Biomarkers ...
http://www.rndsystems.com/molecule_group.aspx?r=1&g=951...

Thumbshot

Search Bioportfolio and other Life Science Sites for MUC16, or search for MUC16 on BioPortfolio's antibody search engine.
This page has been viewed 501 times
Recent Search Terms used to find this page:
muc16 | mucin-16 cancer | mucin 16 | muc16 | MUCIN 16 patent | antibody CA 125 | muc16 | MUC16 pancreatic | Struttura di MUC 16(CA 125). | .


Resources from the NCBI used on this page, NCBI's standard disclaimer applies.

 

Nothing in this website should be used in place of personal medical advice from your own qualified medical practitioner.

All rights reserved. All other trademarks recognized.
Copyright 1997-2009 - BioPortfolio Limited.