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ABCG2
| Symbol: | ABCG2 | | Name(s): | ATP-binding cassette, sub-family G (WHITE), member 2 | | Type: | protein-coding | | Organism: | Homo sapiens | | Synonyms: | ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, MGC102821, MRX, MXR, MXR1 | | Links: |
Pubmed,
Entrez Gene,
GeneCards,
BioGPS,
Map Viewer.
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Gene Information from Publications |
| Publication Link |
Summary of findings |
| 18056989 |
Pim-1 kinase phosphorylates BCRP/ABCG2 and thereby promotes its multimerization and drug-resistant activity in human prostate cancer cells |
| 18207572 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18221820 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18240903 |
Observational study of genotype prevalence. (HuGE Navigator) |
| 18256692 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 18309947 |
Observational study of gene-disease association and pharmacogenomic / toxicogenomic. (HuGE Navigator) |
| 17690695 |
imatinib does not interact at the ATP-binding sites of either Pgp or ABCG2 despite their strong affinity for the ATP-binding pocket of the tyrosine kinases; it behaves like a transport substrate as it stimulates ATP hydrolysis by these transporters |
| 17976197 |
We describe a novel nonsense mutation in exon 10 of the ABCG5 gene in a 10-year-old girl showing clinical and biochemical features of sitosterolaemia |
| 17923155 |
This is the first evidence to clearly indicate that glyburide is preferentially transported by BCRP, in the brush border of the human placenta. |
| 12960109 |
Observational study of gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator) | →View more information from publications. |
Recent Publications on ABCG2: |  |
Characterisation of the activated liver progenitor cell niche, potential involvement of Wnt and Notch signalling.
BACKGROUND: Hepatic progenitor cells (HPCs) hold a great potential for... | 3rd November, 2009
| Belgium;
| Gut. 2009 Nov 1.
DOI Direct Link |
[Hepatotoxicity of statins]
The ability of cancer cells to acquire resistance to multiple anticancer... | 31st October, 2009
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| Orv Hetil. 2009 Sep 13;150(37):1754-5; author reply 1755.
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Human ABC transporter ABCG2 in cancer chemotherapy and pharmacogenomics.
The ability of cancer cells to acquire resistance to multiple anticancer... | 29th October, 2009
| Graduate School of Bioscience and Biotechnology, Tokyo Institute of
| J Exp Ther Oncol. 2009;8(1):5-24.
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Effects of alpha-adrenoceptor antagonist doxazosin on MDR1-mediated multidrug resistance and transcellular transport.
The purpose of this study is to examine the effects of doxazosin, an... | 23rd October, 2009
| Frontier Education Center, Graduate School of Pharmaceutical Sciences,
| Oncol Res. 2009;17(11-12):527-33.
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Different effects of the ABCG2 c.421C>A SNP on the pharmacokinetics of fluvastatin, pravastatin and simvastatin.
AIMS: This study aimed to investigate possible effects of the ABCG2... | 22nd October, 2009
| Department of Clinical Pharmacology, Helsinki University Central Hospital,
| Pharmacogenomics. 2009 Oct;10(10):1617-24.
DOI Direct Link |
→View more research publications. |
ABCG2 results (if any) from reagent suppliers | 
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BCRP/ABCG2 antibody [BXP-9] (ab24114) | Abcam
Rat monoclonal [BXP-9] to BCRP/ABCG2. An ABC transporter. Allows efflux of Hoechst dye, a property that has been used to separate bone marrow side ...
http://www.abcam.com/BCRP-ABCG2-antibody-BXP-9-ab24114.html...
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ABCG2 (5D3) Antibody sc-18841
See how others have used ABCG2 (5D3): sc-18841 antibody and or ABCG2 (5D3) antibody ... ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid ...
http://www.scbt.com/datasheet-18841-abcg2-5d3-antibody.html...
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human ABCG2 antibody, Functional Grade™ Purified conjugate
eBioscience technical data sheet for product 16-8888 Functional Grade Purified anti-human ABCG2 (CD338, Bcrp1, MXR) 5D3 antibody.
http://www.ebioscience.com/ebioscience/specs/antibody_16/16-...
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BCRP/ABCG2 antibody [BXP-34] - Hematopoietic/Neural Stem Cell ...
Mouse monoclonal [BXP-34] to BCRP/ABCG2 - Hematopoietic/Neural Stem Cell Marker. An ABC transporter. Allows efflux of Hoechst dye, a property that has been ...
http://www.abcam.com/BCRP-ABCG2-antibody-BXP-34-Hematopoieti...
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Anti-ABCG2 Monoclonal Antibody
Monoclonal Antibody against ABCG2 for use in Flow Cytometry, Immunocytochemistry , Immunohistochemistry, Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...
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Pacific Blue Anti-human CD338 ABCG2 Antibody Anti-CD338 - BioLegend
Pacific Blue Anti-human CD338 ABCG2 Antibody Anti-CD338 - CD338, known as ABCG2 (BCRP1), is a multi-drug resistance (MDR) family protein that is a member of ...
http://www.biolegend.com/pacific-blue-anti-human-cd338-abcg2...
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ABCG2 (BXP-21) Antibody sc-58222
See how others have used ABCG2 (BXP-21): sc-58222 antibody and or ABCG2 ... Western blot analysis of ABCG2 expression in non-transfected: sc-117752 (A) and
...
http://www.scbt.com/datasheet-58222-abcg2-bxp-21-antibody.ht...
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