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QKI


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Gene DB Home
Symbol:QKI
Name(s):quaking homolog, KH domain RNA binding (mouse)
Type:protein-coding
Organism:Homo sapiens
Synonyms:DKFZp586I0923, Hqk, QK, QK1, QK3
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
17012699 Since QKI plays a fundamental role in oligodendrocyte differentiation and in myelination, its underexpression may be pivotal to, and upstream of, other myelin-associated gene expression abnormalities in schizophrenia.
17079655 QKI-6 is the major protein isoform responsible for central nervous system (CNS) myelination, which promotes myelin basic protein expression in oligodendrocytes.
16641098 QKI levels may regulate oligodendrocyte differentiation and maturation in human brain
16342280 QKI as a possible target for functional studies related to the role of myelination in schizophrenia.
10535969 There are many isoforms of this RNA binding protein. QKI-6 has been shown to be a translational repressor.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDHMT1 hnRNP methyltransferase-like 2 isoform 1QKI--Pubmed
HPRDquaking homolog, KH domain RNA binding isoform HQK-5deleted in azoospermia 4 isoform 1--Pubmed

Recent Publications on QKI:

Pubmed Logo
Expressed sequence tag analysis of adult human optic nerve for NEIBank: identification of cell type and tissue markers.
BACKGROUND: The optic nerve is a pure white matter central nervous system...
26th September, 2009
Department of Ophthalmology, University of Maryland School of Medicine, BMC Neurosci. 2009 Sep 24;10:121.
DOI Direct Link
Essential function, sophisticated regulation and pathological impact of the selective RNA-binding protein QKI in CNS myelin development.
The selective RNA-binding protein QKI play a key role in advancing...
4th September, 2009
Department of Pharmacology, Emory University School of Medicine, 1510 Future Neurol. 2008 Nov;3(6):655-668.
DOI Direct Link
RNA-Binding Protein Quaking, a Critical Regulator of Colon Epithelial Differentiation and a Suppressor of Colon Cancer.
BACKGROUND & AIMS: Colon cancer is one of the best understood neoplasms...
19th August, 2009
Department of Biochemistry and Molecular Biology, the State Key Laboratory Gastroenterology. 2009 Aug 15.
DOI Direct Link
The STAR RNA binding proteins GLD-1, QKI, SAM68 and SLM-2 bind bipartite RNA motifs.
BACKGROUND: SAM68, SAM68-like mammalian protein 1 (SLM-1) and 2 (SLM-2)...
9th July, 2009
Bloomfield Center for Research on Aging, Lady Davis Institute for Medical BMC Mol Biol. 2009 May 20;10:47.
DOI Direct Link
Characterization of QKI gene expression, genetics, and epigenetics in suicide victims with major depressive disorder.
BACKGROUND: A number of studies have suggested deficits in myelination and...
24th June, 2009
McGill Group for Suicide Studies, Douglas Hospital, McGill University, Biol Psychiatry. 2009 Nov 1;66(9):824-31. Epub 2009 Jul 9.
DOI Direct Link

View more research publications.

Patents:

Patents logo
US Patent No.Title
7608395 Systemic lupus erythematosus diagnostic assay
7122373 Human genes and gene expression products V
7026121 Methods and compositions for diagnosing and monitoring transplant rejection
6974667 Gene expression profiles in liver cancer
6914131 Neisserial antigens

View more patents.

QKI results (if any) from reagent suppliers

Google CSE Logo
QKI Antibody / QKI Antibodies
QKI Antibody / QKI Antibodies. ... QKI spezifische siRNA, sHRNA Plasmide und shRNA Lentivirale Partikel Gen Silencer sind ebenfalls erhältlich. ...
http://www.scbt.com/de/table-qki.html...

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Q
SAB2500847, Anti-QUAKING/QKI antibody produced in goat New, (polyclonal) ... human ... QKI(9444), human, rat, canine, mouse, ELISA (i), WB, pricing ...
https://www.sigmaaldrich.com/etc/controller/controller-page....

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QKI Antibody / QKI Antibodies
QKI Antibody / QKI Antibodies. ... QKI specific siRNA, sHRNA Plasmid과 shRNA Lentiviral Particles gene silencers 도 제공합니다. ...
http://www.scbt.com/ko/table-qki.html...

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QK1 antibody (ab15338) | Abcam
The selective RNA binding protein QKI is essential for myelination in the central nervous system. QKI belongs to the family of signal transduction act...
http://www.abcam.com/QK1-antibody-ab15338.html...

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QKI siRNA (h) sc-95183
Click here for details. suitable control antibody: contact Technical Service for availability of control antibody; sqRT-PCR Primer also available: QKI ...
http://www.scbt.com/ja/datasheet-95183-qki-sirna-h.html...

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Abgent - Stem Cell
AP7044a, Pyruvate Kinase (PKM2) Antibody (N-term), WB, E, H, M. AP2707b, QKI Antibody (C-term), WB, E, H. AP2707a, QKI Antibody (N-term), WB, IHC, E, H ...
http://www.abgent.com/products/category/stem_cell...

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QKI Antibody / QKI Antibodies
QKI El siRNA, el plásmido del sHRNA y los silenciadores especificos del gene de las partículas de Lentiviral del shRNA están también disponibles. ...
http://www.scbt.com/es/table-qki.html...

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