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CD38


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Gene DB Home
Symbol:CD38
Name(s):CD38 molecule
Type:protein-coding
Organism:Homo sapiens
Synonyms:T10
Links: Pubmed, Entrez Gene, GeneCards, BioGPS, Map Viewer.

Gene Information from Publications

Publication Link Summary of findings
18322442 Regardless of CD38 expression level, CD38 and ZAP-70 expressions were significantly associated in B-CLL
18178673 These results indicate a critical role for CD38 in TNFalpha-induced enhancement of [Ca(2+)](i) in human airway smooth muscle cells.
12242463 Observational study of gene-disease association. (HuGE Navigator)
15219386 Observational study of gene-disease association. (HuGE Navigator)
16369895 Observational study of gene-disease association. (HuGE Navigator)
16909600 Observational study of gene-disease association. (HuGE Navigator)
18162778 staining for TCL1, CD38, and CD44 are useful ancillary tests to identify B-cell tumors
17931624 Results suggest that Zap-70 expression may be a better indicator of the mutational status of IgVH and prognosis of chronic lymphocytic leukemia than CD38 expression.
18024373 CD38 and ZAP-70 are expressed in lymph node leukemic cells in both good and poor prognosis patients
17684154 CD38 expression labels an activated subset within chronic lymphocytic leukemia clones enriched in proliferating B cells.

View more information from publications.

Interacting gene products

Interaction Type Gene 1 Gene 2 Interaction description Complex Publication Link
HPRDCD4 antigen precursorCD38 antigen--Pubmed
HPRDCD4 antigen precursorCD38 antigen--Pubmed
HPRDCD38 antigenplatelet/endothelial cell adhesion molecule--Pubmed
HPRDCD38 antigenFc fragment of IgG, low affinity IIIa, receptor for--Pubmed
HPRDCD38 antigenFc fragment of IgG, low affinity IIIa, receptor for--Pubmed
HPRDCD38 antigenlymphocyte-specific protein tyrosine kinase--Pubmed
HPRDCD38 antigenlymphocyte-specific protein tyrosine kinase--Pubmed

Recent Publications on CD38:

Pubmed Logo
Evaluation of four methods for processing human cord blood and subsequent study of the expansion of progenitor stem cells isolated using the best method.
Background aims The application of cord blood (CB)-derived hematopoietic...
3rd November, 2009
Stem Cell Biology Laboratory, National Institute of Immunology, Aruna Asaf Cytotherapy. 2009;11(6):768-77.
Immune changes in post-menopausal osteoporosis: the Immunos study.
The phenotypic and functional characteristics of immune cells of...
31st October, 2009
Service de Rhumatologie, CHU de Nice, Hopital l'Archet, Route Saint Osteoporos Int. 2009 Oct 30.
DOI Direct Link
CD40-activated B cells from patients with systemic lupus erythematosus can be modulated by therapeutic immunoglobulins in vitro.
INTRODUCTION: Aberrant signaling within and between B and T cells,...
30th October, 2009
Recherche et developpement, Hema-Quebec, Ingenierie cellulaire, 1070, Arch Immunol Ther Exp (Warsz). 2009 Oct 29.
DOI Direct Link
[The relationship between multi-drug resistance and proportion of leukemia stem cells and expression of drug transporters in drug-resistant leukemia K562/ADM cells]
OBJECTIVE: To investigate the drug resistance, proportion of leukemia stem...
30th October, 2009
Laboratory Center for Medical Science, School of Medicine, Lanzhou Zhonghua Yi Xue Za Zhi. 2009 Jul 7;89(25):1741-4.
Maxillofacial mass as the first presentation of acute lymphoblastic leukemia in a nine-year-old girl.
A nine-year-old girl complained of a maxillofacial mass and mild fever...
27th October, 2009
Department of Otolaryngology, 2nd Affiliated Hospital of Chinese PLA Auris Nasus Larynx. 2009 Oct 23.
DOI Direct Link

View more research publications.

Press Releases on CD38:

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Genmab A/S: Ofatumumab Pivotal CLL Data to be Presented at ASH 10th November, 2008

COPENHAGEN, November 10 /PRNewswire/ -- Genmab A/S (OMX: GEN) announced today that three ofatumumab (HuMax-CD20(R)) abstracts have been accepted for presentation at the 50th American Society of

Genmab Reaches Milestone in Ofatumumab Collaboration 10th October, 2008

COPENHAGEN, Denmark, October 10 /PRNewswire/ -- Genmab A/S (OMX: GEN) announced today it has reached the sixth milestone for ofatumumab (HuMax-CD20(R)) under the terms of its collaboration with

Genmab Announces 2008 First Half Year Results 27th August, 2008

COPENHAGEN, August 27 /PRNewswire/ -- Genmab A/S (OMX: GEN) announced today results for the six month period ended June 30, 2008. During this period, Genmab reported the following results:

Genmab Announces Upcoming Ofatumumab Studies 25th August, 2008

COPENHAGEN, Denmark, August 25 /PRNewswire/ -- Genmab has announced plans to begin four studies of ofatumumab in chronic lymphocytic leukemia and non-Hodgkin's lymphoma.

Genmab A

Genmab Reaches Fifth Milestone in Ofatumumab Collaboration 21st August, 2008

COPENHAGEN, August 21 /PRNewswire/ -- Genmab A/S (OMX: GEN) announced today it has reached the fifth milestone for ofatumumab (HuMax-CD20(R)) under the terms of its collaboration with

BioNews Results for CD38

: RSS Logo
BioPortfolio Logo
Genmab to Present Data from Multiple Studies at ASH
Pharma Live:  Nov 12 2009 12:04AM Matching: cd38

Clinical Trials:

Clinical Trials Logo
HuMax-CD38 Safety Study in Multiple Myeloma

Patents:

Patents logo
US Patent No.Title
7544357 Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays
7560263 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
7563433 Methods and compositions for F-18 labeling of proteins, peptides and other molecules
7563444 Nucleic acid and corresponding protein entitled 213P1F11 useful in treatment and detection of cancer
7563584 Methods and compositions for detecting the activation state of multiple proteins in single cells

View more patents.

CD38 results (if any) from reagent suppliers

Google CSE Logo
CD38 antibody [NIMR-5] (FITC) (ab25667) | Abcam
Rat monoclonal [NIMR-5] to CD38 (FITC). CD38 (T10) is a single chain 42 to 46 kDa type II integral transmembrane glycoprotein with a short N terminal ...
http://www.abcam.com/CD38-antibody-NIMR-5-FITC-ab25667.html...

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CD38 Antibody / CD38 Antibodies
CD38 Antibody / CD38 Antibodies. ... CD38 specific siRNA, sHRNA Plasmid and shRNA Lentiviral Particles gene silencers are also available. ...
http://www.scbt.com/table-cd38.html...

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Anti-CD38 Monoclonal Antibody
Monoclonal Antibody against CD38 for use in Flow Cytometry, Immunohistochemistry (Frozen), Western Blot.
http://www.bioreagents.com/products/productDetails/productDe...

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CD38 (AT1) Antibody sc-7325
CD38 is critical for social behaviour by regulating oxytocin secretion. Nature. ... NAADP as a second messenger: neither CD38 nor base-exchange reaction are ...
http://www.scbt.com/datasheet-7325-cd38-at1-antibody.html...

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PE/Cy7 Anti-mouse CD38 Antibody Anti-CD38 - BioLegend
PE/Cy7 Anti-mouse CD38 Antibody Anti-CD38 - CD38 is a 42 kD glycoprotein, also known as T10.
http://www.biolegend.com/pe-cy7-anti-mouse-cd38-antibody-392...

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CD38 (HB-7) Antibody sc-18858
CD38 (HB-7): sc-18858. Immunofluorescence staining of methanol-fixed ... Western blot analysis of CD38 expression in CCRF-CEM whole cell lysate under ...
http://www.scbt.com/datasheet-18858-cd38-hb-7-antibody.html...

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PE Anti-human CD38 Antibody Anti-CD38 - BioLegend
PE Anti-human CD38 Antibody Anti-CD38 - CD38 is a 45 kD type II transmembrane glycoprotein, also known as T10.
http://www.biolegend.com/pe-anti-human-cd38-antibody-746.htm...

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